Since August 4, 2024, the Chicago Cubs have the highest run differential by a team, with a differential of 175 runs.

	TEAM	DIFF	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	175	115	.600	69	46	3,972	630	1,029	201	25	147	609	417	32	900	132	25	4,468	1,721	373	11	36	15	59	.259	.332	.433	.765
2	Tigers	155	117	.650	76	41	3,963	539	982	186	24	124	518	374	37	1,093	49	16	4,405	1,588	334	5	26	9	63	.248	.317	.401	.717
3	Dodgers	136	118	.627	74	44	4,049	668	1,084	209	20	187	643	419	41	942	107	18	4,559	1,894	416	8	42	25	81	.268	.339	.468	.807
4	Mets	130	118	.619	73	45	3,933	538	962	189	18	148	516	399	77	979	80	13	4,451	1,631	355	5	37	17	91	.245	.323	.415	.738
5	Yankees	122	114	.588	67	47	3,846	585	966	186	10	173	560	480	45	990	91	23	4,416	1,691	369	4	41	35	81	.251	.338	.440	.778
6	Brewers	73	119	.555	66	53	3,965	549	935	167	21	123	515	428	39	1,043	161	34	4,480	1,513	311	21	27	17	61	.236	.314	.382	.696
7	Astros	72	116	.578	67	49	3,930	495	1,009	165	9	131	466	342	49	894	64	18	4,362	1,585	305	12	29	22	100	.257	.322	.403	.725
8	Padres	68	115	.609	70	45	3,875	510	985	185	14	121	476	350	37	784	96	20	4,321	1,561	320	28	31	10	75	.254	.320	.403	.722
9	Giants	56	116	.543	63	53	3,853	477	882	177	17	124	454	349	37	1,055	71	20	4,281	1,465	318	14	28	8	78	.229	.297	.380	.677
10	Braves	44	117	.487	57	60	3,989	503	985	176	10	146	485	398	40	1,019	56	17	4,458	1,619	332	10	21	11	84	.247	.320	.406	.726
11	Diamondbacks	40	117	.530	62	55	3,993	648	1,046	201	22	178	625	447	60	909	97	28	4,567	1,825	401	25	42	11	86	.262	.342	.457	.799
12	Phillies	36	118	.576	68	50	4,016	551	1,032	211	15	132	524	371	44	956	98	20	4,467	1,669	358	13	23	12	84	.257	.325	.416	.740
13	Mariners	35	115	.513	59	56	3,878	515	923	159	5	139	495	424	80	1,072	116	27	4,430	1,509	303	17	31	11	74	.238	.323	.389	.712
14	Rays	35	118	.508	60	58	3,936	461	927	175	13	111	435	329	36	1,045	155	29	4,337	1,461	299	5	31	12	58	.236	.298	.371	.669
15	Cardinals	18	117	.530	62	55	3,977	511	1,010	217	11	109	489	372	44	909	66	23	4,436	1,576	337	10	33	15	85	.254	.322	.396	.718
16	Reds	12	119	.487	58	61	3,982	524	965	188	14	124	504	398	48	1,056	109	33	4,468	1,553	326	11	29	8	68	.242	.317	.390	.707
17	Blue Jays	12	116	.500	58	58	3,925	488	980	205	15	120	470	374	53	844	53	16	4,398	1,575	340	17	29	21	85	.250	.321	.401	.722
18	Red Sox	-6	120	.458	55	65	4,124	551	1,012	220	11	140	530	390	53	1,140	100	27	4,597	1,674	371	6	24	25	82	.245	.317	.406	.723
19	Twins	-9	118	.475	56	62	3,967	487	945	194	13	117	461	333	66	967	44	17	4,401	1,516	324	5	30	9	76	.238	.306	.382	.688
20	Royals	-12	116	.500	58	58	3,903	428	958	190	20	94	416	293	36	867	94	31	4,290	1,470	304	20	38	16	63	.245	.301	.377	.678
21	Guardians	-24	116	.509	59	57	3,804	449	883	154	12	127	428	356	44	927	109	29	4,251	1,442	293	13	34	17	65	.232	.303	.379	.682
22	Rangers	-38	117	.479	56	61	3,869	431	877	149	8	123	413	311	38	978	97	24	4,246	1,411	280	3	25	6	59	.227	.289	.365	.654
23	Orioles	-87	114	.447	51	63	3,836	465	913	160	16	133	438	342	43	1,009	75	18	4,259	1,504	309	4	34	7	68	.238	.305	.392	.697
24	Nationals	-98	116	.440	51	65	3,840	464	929	189	15	109	439	312	49	870	126	44	4,245	1,475	313	20	24	3	78	.242	.305	.384	.689
25	White Sox	-116	115	.313	36	79	3,807	395	861	158	5	90	381	335	22	969	66	27	4,205	1,299	253	13	28	4	66	.226	.291	.341	.632