biggest margin of victory in a single game for the cardinals

The St. Louis Cardinals had their highest run differential in a game against the Phillies on July 6, 1929, with a differential of 22 runs.

Interpreted as:

biggest margin of victory in a single regular-season game for the cardinals

	TEAM	DIFF	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cardinals	22	7/6/1929	SLN	@	PHN	W 28-6	53	28	28	4	1	2	25	9	1	1	0	0	65	40	7	2				.528	.603	.755	1.358
2	Browns	21	6/1/1895	STL	@	NYG	W 23-2		23
3	Cardinals	20	9/16/1926	SLN	@	PHN	W 23-3	49	23	22	5	0	0	18	8	0	5	5	0	57	27	5	0				.449	.526	.551	1.077
4	Cardinals	18	4/27/1977	STL	@	CHC	W 21-3	48	21	19	6	0	1	18	8	1	7	0	0	57	28	7	0	0	3	0	.396	.491	.583	1.075
5	Cardinals	18	6/10/1944	SLN	@	CIN	W 18-0	48	18	21	2	0	0	17	14	0	2	2	0	63	23	2	1			0	.438	.565	.479	1.044
6	Cardinals	18	7/24/1937	SLN	@	BKN	W 20-2	46	20	18	2	1	1	19	7	0	2	0	0	54	25	4	1			1	.391	.472	.543	1.015
7	Cardinals	17	5/15/2023	STL	vs	MIL	W 18-1	38	18	16	2	0	4	18	8	1	7	0	0	48	30	6	0	1	0	1	.421	.521	.789	1.310
8	Cardinals	17	7/4/1945	SLN	@	NYG	W 19-2	44	19	20	1	1	2	18	7	1	4	0	0	53	29	4	1			0	.455	.538	.659	1.198
9	Cardinals	17	8/24/1924	SLN	vs	BKN	W 17-0	45	17	25	6	3	0	17	2	0	4	0	1	49	37	9	2				.556	.574	.822	1.397
10	Cardinals	17	7/3/1904	SLN	@	CHC	W 19-2	49	19	20	3	2	1		3	0	3	2		52	30	6	0				.408	.442	.612	1.055
11	Browns	17	7/25/1895	STL	vs	BKN	W 20-3		20
12	Browns	17	7/15/1892	STL	@	BSN	W 20-3		20
13	Cardinals	16	8/11/1980	STL	vs	MON	W 16-0	38	16	16	4	2	2	14	4	0	6	1	0	44	30	8	0	2	0	0	.421	.455	.789	1.244
14	Cardinals	16	8/2/1948	SLN	@	NYG	W 21-5	48	21	20	8	0	4	20	10	1	0	0	0	59	40	12	0			0	.417	.525	.833	1.359
15	Cardinals	16	7/3/1946	SLN	vs	CIN	W 16-0	37	16	15	4	0	1	16	9	0	2	1	0	46	22	5	0			1	.405	.522	.595	1.116
16	Cardinals	16	6/24/1944	SLN	@	PIT	W 16-0	48	16	22	5	0	1	14	7	0	1	1	0	57	30	6	2			0	.458	.527	.625	1.152
17	Cardinals	16	5/7/1940	SLN	vs	BKN	W 18-2	43	18	20	4	2	7	18	0	3	1	1	0	47	49	13	1			1	.465	.500	1.140	1.640
18	Browns	16	5/26/1895	STL	vs	WSH	W 23-7		23
19	Cardinals	15	8/22/2008	STL	vs	ATL	W 18-3	44	18	26	5	0	0	18	9	0	6	0	2	55	31	5	1	1	2	1	.591	.648	.705	1.353
20	Cardinals	15	5/20/2000	STL	@	PIT	W 19-4	46	19	19	2	1	3	16	6	2	7	1	0	55	32	6	0	1	0	1	.413	.491	.696	1.187
21	Cardinals	15	5/17/1975	STL	@	SFG	W 17-2	46	17	23	6	2	2	17	5	0	7	0	0	52	39	10	0	1	0	2	.500	.538	.848	1.386
22	Cardinals	15	4/23/1963	STL	@	HOU	W 15-0	43	15	17	1	2	0	13	6	0	3	2	0	52	22	3	2	1	0	1	.395	.460	.512	.972
23	Cardinals	15	5/7/1950	SLN	vs	BSN	W 15-0	46	15	21	5	2	1	14	4	0	2	2	0	50	33	8	0		0	0	.457	.500	.717	1.217
24	Cardinals	15	5/23/1948	SLN	@	PHN	W 18-3	47	18	17	4	2	1	15	12	0	4	1	0	59	28	7	0			0	.362	.492	.596	1.087
25	Cardinals	15	6/29/1947	SLN	vs	CIN	W 17-2	39	17	14	3	0	1	17	10	0	1	0	0	49	20	4	0			0	.359	.490	.513	1.003