The Cincinnati Reds had the highest run differential by a team in a game in 2025, with a differential of 22 runs versus the Orioles on April 20, 2025.

Interpreted as:

biggest win margin in one regular-season game in 2025

	TEAM	DIFF	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Reds	22	4/20/2025	CIN	@	BAL	W 24-2	51	24	25	4	1	3	23	11	2	6	1	0	64	40	8	0	0	0	1	.490	.594	.784	1.378
2	Padres	21	5/10/2025	SDP	@	COL	W 21-0	50	21	24	4	1	5	20	5	0	4	0	0	56	45	10	0	1	0	0	.480	.518	.900	1.418
3	Royals	19	9/19/2025	KCR	vs	TOR	W 20-1	51	20	27	7	0	3	20	5	0	6	1	0	56	43	10	0	0	0	0	.529	.571	.843	1.415
4	Blue Jays	19	8/6/2025	TOR	@	COL	W 20-1	49	20	24	7	1	5	20	4	2	6	0	0	57	48	13	0	2	0	0	.490	.526	.980	1.506
5	Orioles	18	7/26/2025	BAL	vs	COL	W 18-0	40	18	18	4	0	3	16	6	1	4	1	0	47	31	7	0	0	0	3	.450	.532	.775	1.307
6	Rangers	17	8/27/2025	TEX	vs	LAA	W 20-3	46	20	22	5	0	4	20	4	2	6	0	0	53	39	9	0	1	0	0	.478	.528	.848	1.376
7	Astros	17	7/4/2025	HOU	@	LAD	W 18-1	44	18	20	6	0	5	17	8	1	8	0	1	54	41	11	0	1	1	1	.455	.537	.932	1.469
8	Dodgers	17	5/15/2025	LAD	vs	ATH	W 19-2	40	19	18	2	0	5	19	8	0	6	2	0	50	35	7	0	2	0	0	.450	.520	.875	1.395
9	Mariners	16	9/7/2025	SEA	@	ATL	W 18-2	45	18	19	1	1	5	14	3	2	7	2	0	51	37	7	0	1	0	1	.422	.471	.822	1.293
10	Dodgers	16	5/31/2025	LAD	vs	NYY	W 18-2	43	18	21	5	0	5	18	7	0	5	0	0	51	41	10	0	1	0	1	.488	.549	.953	1.503
11	Cubs	16	4/12/2025	CHC	@	LAD	W 16-0	47	16	21	5	0	4	16	4	1	4	1	0	53	38	9	0	1	0	0	.447	.491	.809	1.299
12	Phillies	15	8/28/2025	PHI	vs	ATL	W 19-4	44	19	20	3	1	7	19	4	0	3	0	0	48	46	11	0	0	0	0	.455	.500	1.045	1.545
13	Rays	15	4/14/2025	TBR	vs	BOS	W 16-1	40	16	16	2	0	4	16	4	0	9	1	0	44	30	6	0	0	0	1	.400	.455	.750	1.205
14	Brewers	15	4/9/2025	MIL	@	COL	W 17-2	40	17	13	2	0	3	15	5	0	6	3	0	46	24	5	0	1	0	1	.325	.391	.600	.991
15	Cubs	15	3/31/2025	CHC	@	ATH	W 18-3	48	18	21	6	1	4	18	10	1	7	0	0	60	41	11	0	1	0	0	.438	.533	.854	1.388
16	Brewers	14	8/12/2025	MIL	vs	PIT	W 14-0	40	14	15	4	0	5	14	5	0	8	0	0	46	34	9	0	1	0	0	.375	.435	.850	1.285
17	Blue Jays	14	8/4/2025	TOR	@	COL	W 15-1	50	15	25	4	1	3	15	3	0	5	0	0	53	40	8	0	0	0	2	.500	.528	.800	1.328
18	Red Sox	14	6/28/2025	BOS	vs	TOR	W 15-1	40	15	18	6	0	3	14	6	2	7	2	0	50	33	9	0	2	0	0	.450	.520	.825	1.345
19	Orioles	14	6/27/2025	BAL	vs	TBR	W 22-8	46	22	21	9	1	4	20	8	1	9	2	0	55	44	14	0	0	0	0	.457	.545	.957	1.502
20	Red Sox	14	5/23/2025	BOS	vs	BAL	W 19-5	45	19	20	6	0	3	19	8	0	7	0	0	53	35	9	0	0	0	1	.444	.528	.778	1.306
21	Blue Jays	14	5/21/2025	TOR	vs	SDP	W 14-0	40	14	14	3	0	2	13	3	2	7	1	0	46	23	5	1	0	0	0	.350	.422	.575	.997
22	Mets	14	4/28/2025	NYM	@	WSH	W 19-5	47	19	21	3	1	4	19	6	2	9	0	0	56	38	8	0	1	0	0	.447	.518	.809	1.326
23	Mariners	14	4/26/2025	SEA	vs	MIA	W 14-0	37	14	15	3	0	4	14	7	1	6	0	0	46	30	7	0	1	0	0	.405	.500	.811	1.311
24	Athletics	13	9/6/2025	ATH	@	LAA	W 17-4	49	17	21	4	0	4	17	6	1	8	1	0	56	37	8	0	0	0	0	.429	.500	.755	1.255
25	Red Sox	13	8/12/2025	BOS	@	HOU	W 14-1	40	14	13	2	0	3	14	8	2	5	2	0	51	24	5	0	1	0	0	.325	.451	.600	1.051

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More Reds Stats

Team Batting Leaders

25

Stewart

RBI

87

Stewart

AVG

.274

De La Cruz

Team Pitching Leaders

13

Burns

143

Burns

ERA

2.61

Burns

Team Rankings

154

5th

481

26th

929

23rd

ERA

4.45

23rd

2026 Division Standings

TEAM	W	L	PCT	GB
Brewers	73	44	.624
Cubs	68	50	.576	5.5
Cardinals	58	58	.500	14.5
Pirates	58	61	.487	16.0
Reds	56	60	.483	16.5

Schedule

DATE	MATCHUP			TIME (ET)
Sun 8/9	CIN	@	WSH	12:15 PM
Tue 8/11	CIN	@	CWS	7:40 PM
Wed 8/12	CIN	@	CWS	7:40 PM
Thu 8/13	CIN	@	CWS	2:10 PM
Fri 8/14	MIA	@	CIN	6:10 PM

Last Game

Reds

56 - 60

Final

Nationals

58 - 61

Sat 8 Aug 2026

MLB 2026 Batting Leaders

HR Leaders

35

Alvarez

33

Caminero

33

Goodman

RBI Leaders

89

Abrams

87

Stewart

86

Alvarez

Batting Average Leaders

.325

Alvarez

.323

Arraez

.317

Lopez

Hit Leaders

145

Lopez

141

Arraez

137

Alvarez

Run Leaders

100

Wood

82

Crow-Armstrong

82

Olson

OBP Leaders

.439

Alvarez

.400

Ohtani

.396

Kurtz

SLG Leaders

.630

Alvarez

.556

García

.556

Caminero

SB Leaders

40

Nuñez

31

Witt

30

Simpson

MLB 2026 Pitching Leaders

Win Leaders

15

Sánchez

14

Gray

13

Burns

Strikeout Leaders

195

Misiorowski

184

Cease

178

Williams

ERA Leaders

1.63

Misiorowski

2.20

Sale

2.26

Schlittler

WHIP Leaders

0.73

Misiorowski

0.88

Yamamoto

0.91

Rasmussen

K/9 Leaders

13.82

Misiorowski

13.11

Cease

11.53

Williams

K/BB Leaders

6.72

Misiorowski

5.91

Rasmussen

5.52

Schlittler

Walk Leaders

20

Martinez

22

Rasmussen

24

Wrobleski

MLB Fantasy 2026

FanDuel Points Leaders

1,995.6

Ohtani

1,661.5

Wood

1,638.9

Crow-Armstrong

DraftKings Points Leaders

1,388.6

Ohtani

1,248

Crow-Armstrong

1,234

Wood

MLB 2026 Betting

Best Record ATS

68-47

69-50

65-50

65-53

63-53

63-54

Worst Record ATS

44-73

47-70

49-67

52-65

54-64

54-63

MLB 2026 Standings

NL East	W	L	PCT	GB
Braves	70	47	.598
Phillies	62	55	.530	8.0
Marlins	59	59	.500	11.5
Nationals	58	61	.487	13.0
Mets	51	67	.432	19.5
NL Central	W	L	PCT	GB
Brewers	73	44	.624
Cubs	68	50	.576	5.5
Cardinals	58	58	.500	14.5
Pirates	58	61	.487	16.0
Reds	56	60	.483	16.5
NL West	W	L	PCT	GB
Dodgers	69	47	.595
Diamondbacks	62	55	.530	7.5
Padres	61	57	.517	9.0
Giants	49	67	.422	20.0
Rockies	45	71	.388	24.0

AL East	W	L	PCT	GB
Rays	69	46	.600
Yankees	66	51	.564	4.0
Red Sox	64	52	.552	5.5
Orioles	56	60	.483	13.5
Blue Jays	55	62	.470	15.0
AL Central	W	L	PCT	GB
White Sox	59	56	.513
Guardians	58	59	.496	2.0
Twins	58	60	.492	2.5
Tigers	56	60	.483	3.5
Royals	49	69	.415	11.5
AL West	W	L	PCT	GB
Astros	60	58	.508
Rangers	58	58	.500	1.0
Mariners	56	61	.479	3.5
Athletics	46	71	.393	13.5
Angels	45	72	.385	14.5

MLB 2026 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Sat 7/25	KCR	@	DET	3-2
Sat 7/25	LAA	@	SFG	2-9
Sat 7/25	AZ	@	WSH	3-5
Sat 7/25	TOR	@	BOS	6-0
Sat 7/25	SDP	@	MIA	7-2

Schedule

DATE	MATCHUP			TIME (ET)
Sat 8/8	TBR	@	SEA	9:50 PM
Sun 8/9	CIN	@	WSH	12:15 PM
Sun 8/9	ATL	@	NYY	1:35 PM
Sun 8/9	ATH	@	BOS	1:35 PM
Sun 8/9	TOR	@	PHI	1:35 PM

The Cincinnati Reds had the highest run differential by a team in a game in 2025, with a differential of 22 runs versus the Orioles on April 20, 2025.

Interpreted as:

Related Searches

More MLB News

More Reds Stats

25

87

.274

13

143

2.61

MLB 2026 Batting Leaders

35

33

33

89

87

86

.325

.323

.317

145

141

137

100

82

82

.439

.400

.396

.630

.556

.556

40

31

30

MLB 2026 Pitching Leaders

15

14

13

195

184

178

1.63

2.20

2.26

0.73

0.88

0.91

13.82

13.11

11.53

6.72

5.91

5.52

20

22

24

MLB Fantasy 2026

1,995.6

1,661.5

1,638.9

1,388.6

1,248

1,234

MLB 2026 Betting

MLB 2026 Standings

MLB 2026 Scores & Schedule

Scores

Schedule