The Cincinnati Reds had the highest run differential by a team in a game in 2025, with a differential of 22 runs against the Orioles on April 20, 2025.
Interpreted as:
biggest win margin in one regular-season game in MLB last year| TEAM | DIFF | DATE | TM | OPP | RESULT | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Reds | 22 | 4/20/2025 | @ | W 24-2 | 51 | 24 | 25 | 4 | 1 | 3 | 23 | 11 | 2 | 6 | 1 | 0 | 64 | 40 | 8 | 0 | 0 | 0 | 1 | .490 | .594 | .784 | 1.378 | ||
| 2 |  | Padres | 21 | 5/10/2025 | @ | W 21-0 | 50 | 21 | 24 | 4 | 1 | 5 | 20 | 5 | 0 | 4 | 0 | 0 | 56 | 45 | 10 | 0 | 1 | 0 | 0 | .480 | .518 | .900 | 1.418 | ||
| 3 |  | Royals | 19 | 9/19/2025 | vs | W 20-1 | 51 | 20 | 27 | 7 | 0 | 3 | 20 | 5 | 0 | 6 | 1 | 0 | 56 | 43 | 10 | 0 | 0 | 0 | 0 | .529 | .571 | .843 | 1.415 | ||
| 4 |  | Blue Jays | 19 | 8/6/2025 | @ | W 20-1 | 49 | 20 | 24 | 7 | 1 | 5 | 20 | 4 | 2 | 6 | 0 | 0 | 57 | 48 | 13 | 0 | 2 | 0 | 0 | .490 | .526 | .980 | 1.506 | ||
| 5 |  | Orioles | 18 | 7/26/2025 | vs | W 18-0 | 40 | 18 | 18 | 4 | 0 | 3 | 16 | 6 | 1 | 4 | 1 | 0 | 47 | 31 | 7 | 0 | 0 | 0 | 3 | .450 | .532 | .775 | 1.307 | ||
| 6 |  | Rangers | 17 | 8/27/2025 | vs | W 20-3 | 46 | 20 | 22 | 5 | 0 | 4 | 20 | 4 | 2 | 6 | 0 | 0 | 53 | 39 | 9 | 0 | 1 | 0 | 0 | .478 | .528 | .848 | 1.376 | ||
| 7 |  | Astros | 17 | 7/4/2025 | @ | W 18-1 | 44 | 18 | 20 | 6 | 0 | 5 | 17 | 8 | 1 | 8 | 0 | 1 | 54 | 41 | 11 | 0 | 1 | 1 | 1 | .455 | .537 | .932 | 1.469 | ||
| 8 |  | Dodgers | 17 | 5/15/2025 | vs | W 19-2 | 40 | 19 | 18 | 2 | 0 | 5 | 19 | 8 | 0 | 6 | 2 | 0 | 50 | 35 | 7 | 0 | 2 | 0 | 0 | .450 | .520 | .875 | 1.395 | ||
| 9 |  | Mariners | 16 | 9/7/2025 | @ | W 18-2 | 45 | 18 | 19 | 1 | 1 | 5 | 14 | 3 | 2 | 7 | 2 | 0 | 51 | 37 | 7 | 0 | 1 | 0 | 1 | .422 | .471 | .822 | 1.293 | ||
| 10 | | Dodgers | 16 | 5/31/2025 | vs | W 18-2 | 43 | 18 | 21 | 5 | 0 | 5 | 18 | 7 | 0 | 5 | 0 | 0 | 51 | 41 | 10 | 0 | 1 | 0 | 1 | .488 | .549 | .953 | 1.503 | ||
| 11 |  | Cubs | 16 | 4/12/2025 | @ | W 16-0 | 47 | 16 | 21 | 5 | 0 | 4 | 16 | 4 | 1 | 4 | 1 | 0 | 53 | 38 | 9 | 0 | 1 | 0 | 0 | .447 | .491 | .809 | 1.299 | ||
| 12 |  | Phillies | 15 | 8/28/2025 | vs | W 19-4 | 44 | 19 | 20 | 3 | 1 | 7 | 19 | 4 | 0 | 3 | 0 | 0 | 48 | 46 | 11 | 0 | 0 | 0 | 0 | .455 | .500 | 1.045 | 1.545 | ||
| 13 |  | Rays | 15 | 4/14/2025 | vs | W 16-1 | 40 | 16 | 16 | 2 | 0 | 4 | 16 | 4 | 0 | 9 | 1 | 0 | 44 | 30 | 6 | 0 | 0 | 0 | 1 | .400 | .455 | .750 | 1.205 | ||
| 14 |  | Brewers | 15 | 4/9/2025 | @ | W 17-2 | 40 | 17 | 13 | 2 | 0 | 3 | 15 | 5 | 0 | 6 | 3 | 0 | 46 | 24 | 5 | 0 | 1 | 0 | 1 | .325 | .391 | .600 | .991 | ||
| 15 | | Cubs | 15 | 3/31/2025 | @ | W 18-3 | 48 | 18 | 21 | 6 | 1 | 4 | 18 | 10 | 1 | 7 | 0 | 0 | 60 | 41 | 11 | 0 | 1 | 0 | 0 | .438 | .533 | .854 | 1.388 | ||
| 16 | | Brewers | 14 | 8/12/2025 | vs | W 14-0 | 40 | 14 | 15 | 4 | 0 | 5 | 14 | 5 | 0 | 8 | 0 | 0 | 46 | 34 | 9 | 0 | 1 | 0 | 0 | .375 | .435 | .850 | 1.285 | ||
| 17 | | Blue Jays | 14 | 8/4/2025 | @ | W 15-1 | 50 | 15 | 25 | 4 | 1 | 3 | 15 | 3 | 0 | 5 | 0 | 0 | 53 | 40 | 8 | 0 | 0 | 0 | 2 | .500 | .528 | .800 | 1.328 | ||
| 18 |  | Red Sox | 14 | 6/28/2025 | vs | W 15-1 | 40 | 15 | 18 | 6 | 0 | 3 | 14 | 6 | 2 | 7 | 2 | 0 | 50 | 33 | 9 | 0 | 2 | 0 | 0 | .450 | .520 | .825 | 1.345 | ||
| 19 | | Orioles | 14 | 6/27/2025 | vs | W 22-8 | 46 | 22 | 21 | 9 | 1 | 4 | 20 | 8 | 1 | 9 | 2 | 0 | 55 | 44 | 14 | 0 | 0 | 0 | 0 | .457 | .545 | .957 | 1.502 | ||
| 20 | | Red Sox | 14 | 5/23/2025 | vs | W 19-5 | 45 | 19 | 20 | 6 | 0 | 3 | 19 | 8 | 0 | 7 | 0 | 0 | 53 | 35 | 9 | 0 | 0 | 0 | 1 | .444 | .528 | .778 | 1.306 | ||
| 21 | | Blue Jays | 14 | 5/21/2025 | vs | W 14-0 | 40 | 14 | 14 | 3 | 0 | 2 | 13 | 3 | 2 | 7 | 1 | 0 | 46 | 23 | 5 | 1 | 0 | 0 | 0 | .350 | .422 | .575 | .997 | ||
| 22 |  | Mets | 14 | 4/28/2025 | @ | W 19-5 | 47 | 19 | 21 | 3 | 1 | 4 | 19 | 6 | 2 | 9 | 0 | 0 | 56 | 38 | 8 | 0 | 1 | 0 | 0 | .447 | .518 | .809 | 1.326 | ||
| 23 | | Mariners | 14 | 4/26/2025 | vs | W 14-0 | 37 | 14 | 15 | 3 | 0 | 4 | 14 | 7 | 1 | 6 | 0 | 0 | 46 | 30 | 7 | 0 | 1 | 0 | 0 | .405 | .500 | .811 | 1.311 | ||
| 24 |  | Athletics | 13 | 9/6/2025 | @ | W 17-4 | 49 | 17 | 21 | 4 | 0 | 4 | 17 | 6 | 1 | 8 | 1 | 0 | 56 | 37 | 8 | 0 | 0 | 0 | 0 | .429 | .500 | .755 | 1.255 | ||
| 25 | | Red Sox | 13 | 8/12/2025 | @ | W 14-1 | 40 | 14 | 13 | 2 | 0 | 3 | 14 | 8 | 2 | 5 | 2 | 0 | 51 | 24 | 5 | 0 | 1 | 0 | 0 | .325 | .451 | .600 | 1.051 | ||
CIN
BAL
SDP
COL
KCR
TOR
TEX
LAA
HOU
LAD
ATH
SEA
ATL
NYY
CHC
PHI
TBR
BOS
MIL
PIT
NYM
WSH
MIASome of the information used here was obtained free of charge from Retrosheet.
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More Reds Stats
Team Batting Leaders 
HR
24
Stewart
RBI
85
Stewart
AVG
.276
De La Cruz
Team Pitching Leaders 
W
13
Burns
K
137
Burns
ERA
2.35
Burns
Team Rankings
HR
145
6th
R
462
26th
SO
890
22nd
ERA
4.41
23rd
Cardinals
MLB 2026 Batting Leaders
MLB 2026 Pitching Leaders
MLB Fantasy 2026
MLB 2026 Betting
MLB 2026 Standings
| NL East | W | L | PCT | GB |
|---|---|---|---|---|
67 | 45 | .598 | ||
60 | 53 | .531 | 7.5 | |
58 | 55 | .513 | 9.5 | |
55 | 59 | .482 | 13.0 | |
47 | 66 | .416 | 20.5 | |
| NL Central | W | L | PCT | GB |
69 | 43 | .616 | ||
64 | 49 | .566 | 5.5 | |
57 | 57 | .500 | 13.0 | |
56 | 57 | .496 | 13.5 | |
53 | 58 | .477 | 15.5 | |
| NL West | W | L | PCT | GB |
69 | 44 | .611 | ||
60 | 53 | .531 | 9.0 | |
58 | 55 | .513 | 11.0 | |
48 | 65 | .425 | 21.0 | |
45 | 68 | .398 | 24.0 |
Diamondbacks
Giants| AL East | W | L | PCT | GB |
|---|---|---|---|---|
66 | 46 | .589 | ||
63 | 50 | .558 | 3.5 | |
60 | 51 | .541 | 5.5 | |
54 | 58 | .482 | 12.0 | |
53 | 60 | .469 | 13.5 | |
| AL Central | W | L | PCT | GB |
59 | 52 | .532 | ||
57 | 56 | .504 | 3.0 | |
56 | 57 | .496 | 4.0 | |
54 | 58 | .482 | 5.5 | |
46 | 67 | .407 | 14.0 | |
| AL West | W | L | PCT | GB |
58 | 56 | .509 | ||
55 | 58 | .487 | 2.5 | |
55 | 58 | .487 | 2.5 | |
45 | 67 | .402 | 12.0 | |
43 | 69 | .384 | 14.0 |
White Sox
Guardians
Twins
Tigers