5 players are tied for the most strikeouts for the Cleveland Indians in a game, with 5 strikeouts. The first three are Daniel Johnson on May 2, 2021, Jim Thome on April 9, 2000 and Rick Manning on May 15, 1977.
| NAME | SO | DATE | TM | OPP | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Johnson | 5 | 5/2/2021 |  CLE | @ |  CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 |  | J. Thome | 5 | 4/9/2000 | CLE | @ |  TBD | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | R. Manning | 5 | 5/15/1977 | CLE | @ |  CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | | L. Doby | 5 | 4/25/1948 | CLE | @ |  DET | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | ||
| 5 | | B. Bernhard | 5 | 8/11/1904 |  CLE | vs |  PHA | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 6 | | K. Manzardo | 4 | 5/3/2025 |  CLE | @ |  TOR | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | L. Thomas | 4 | 4/4/2025 | CLE | @ |  LAA | 5 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 2 | 1 | 0 | 0 | 0 | 0 |
| 8 | | N. Jones | 4 | 4/1/2025 | CLE | @ |  SDP | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | D. Schneemann | 4 | 8/16/2024 | CLE | @ |  MIL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 | | B. Rocchio | 4 | 7/22/2024 | CLE | vs | DET | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 |  | A. Giménez | 4 | 7/9/2024 | CLE | @ | DET | 6 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 0 | 0 | 0 | 1 |
| 12 |  | J. Naylor | 4 | 6/24/2024 | CLE | @ |  BAL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | | G. Arias | 4 | 9/12/2023 | CLE | @ |  SFG | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | | G. Arias | 4 | 6/6/2023 | CLE | vs |  BOS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 | | M. Zunino | 4 | 5/2/2023 | CLE | @ |  NYY | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | M. Zunino | 4 | 4/18/2023 | CLE | @ | DET | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 |  | J. Ramírez | 4 | 4/18/2023 | CLE | @ | DET | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | | B. Naylor | 4 | 10/2/2022 | CLE | vs |  KCR | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19 | | A. Rosario | 4 | 8/28/2022 | CLE | @ |  SEA | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | | F. Reyes | 4 | 7/10/2022 | CLE | @ | KCR | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | | F. Reyes | 4 | 6/21/2022 | CLE | @ |  MIN | 5 | 1 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 0 | 0 | 0 | 0 |
| 22 | | F. Reyes | 4 | 5/9/2022 | CLE | @ | CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | | F. Reyes | 4 | 4/29/2022 | CLE | @ |  OAK | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | F. Reyes | 4 | 4/26/2022 | CLE | @ | LAA | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 | | B. Bradley | 4 | 10/1/2021 | CLE | @ |  TEX | 5 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.
Some of the information used here was obtained free of charge from Retrosheet.
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