Drew Smyly had a record of 3-1 with an ERA of 2.70 and 37 strikeouts in 19 appearances against the Twins in his career.
- Regular season
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Smyly | 5/25/2012 | @ | W | 1 | 5.40 | 2 | 0 | 0 | 0 | 5.0 | 6 | 3 | 4 | 0 | 2 | 0 | 0 | 0 | 23 | 0 | ||
| 2 | | D. Smyly | 9/23/2012 | vs | 1 | 0.00 | 2 | 0 | 0 | 0 | 4.1 | 3 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 19 | 0 | |||
| 3 | | D. Smyly | 9/28/2012 | @ | 1 | 0.00 | 5 | 0 | 0 | 0 | 5.1 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 19 | 0 | |||
| 4 | | D. Smyly | 4/1/2013 | @ | 0 | 13.50 | 1 | 0 | 0 | 0 | 1.1 | 3 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 10 | 1 | |||
| 5 | | D. Smyly | 4/29/2013 | vs | 0 | 0.00 | 0 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | |||
| 6 | | D. Smyly | 4/30/2013 | vs | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | |||
| 7 | | D. Smyly | 5/26/2013 | vs | 0 | 0.00 | 3 | 0 | 0 | 0 | 2.1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 8 | 0 | |||
| 8 | | D. Smyly | 6/14/2013 | @ | 0 | 0.00 | 0 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | |||
| 9 | | D. Smyly | 8/21/2013 | vs | W | 0 | 0.00 | 2 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | ||
| 10 | | D. Smyly | 8/22/2013 | vs | 0 | 0.00 | 0 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | |||
| 11 | | D. Smyly | 9/23/2013 | @ | 0 | 0 | 0 | 0 | 0 | 0.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | ||||
| 12 | | D. Smyly | 9/24/2013 | @ | 0 | 0.00 | 1 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
| 13 | | D. Smyly | 9/25/2013 | @ | 0 | 0.00 | 1 | 0 | 0 | 0 | 0.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | |||
| 14 | | D. Smyly | 6/13/2014 | vs | L | 1 | 1.50 | 2 | 0 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 3 | 0 | 0 | 0 | 24 | 0 | ||
| 15 | | D. Smyly | 8/27/2015 | vs | 1 | 6.23 | 5 | 0 | 0 | 0 | 4.1 | 8 | 3 | 4 | 1 | 2 | 0 | 0 | 0 | 23 | 0 | |||
| 16 | | D. Smyly | 6/5/2016 | @ | 1 | 7.20 | 7 | 0 | 0 | 0 | 5.0 | 7 | 4 | 4 | 2 | 3 | 0 | 0 | 0 | 26 | 0 | |||
| 17 | | D. Smyly | 5/12/2023 | @ | W | 1 | 0.00 | 4 | 0 | 0 | 0 | 6.0 | 5 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 24 | 0 | ||
| 18 | | D. Smyly | 8/6/2024 | vs | 0 | 9.00 | 0 | 0 | 0 | 0 | 1.0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 4 | 0 | |||
| 19 | | D. Smyly | 8/7/2024 | vs | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | |||
| Total | 7 | 2.70 | 37 | 0 | 0 | 0 | 46.2 | 44 | 14 | 19 | 5 | 20 | 0 | 1 | 0 | 205 | 1 |
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