Answered January 12th, 2020

Since 1990, J.R. Phillips has the fewest plate appearances with 50+ strikeouts in a season, with 116 plate appearances in 1996.

fewest plate appearances by a hitter with 50 strikeouts in a season since 1990
Interpreted as:
fewest plate appearances by a hitter with 50 or more strikeouts in a season since 1990

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