highest run difference in an mlb game in 2018

The Washington Nationals had the highest run differential by a team in a game in 2018, with a differential of 21 runs against the Mets on July 31, 2018.

Interpreted as:

highest run difference in an MLB regular-season game in 2018

	TEAM	DIFF	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Nationals	21	7/31/2018	WSH	vs	NYM	W 25-4	50	25	26	5	2	5	25	8	1	6	2	0	59	50	12	0	0	1	0	.520	.593	1.000	1.593
2	Mets	20	8/16/2018	NYM	@	PHI	W 24-4	52	24	25	7	1	3	19	7	1	5	1	0	61	43	11	1	0	1	2	.481	.550	.827	1.377
3	Phillies	19	4/7/2018	PHI	vs	MIA	W 20-1	42	20	20	4	0	4	20	6	0	11	0	0	49	36	8	0	1	0	1	.476	.531	.857	1.388
4	Athletics	18	9/20/2018	OAK	vs	LAA	W 21-3	44	21	22	4	0	3	20	7	0	7	0	0	51	35	7	0	0	0	2	.500	.569	.795	1.364
5	Rockies	17	7/11/2018	COL	vs	ARI	W 19-2	43	19	19	4	1	5	18	6	0	4	1	0	49	40	10	0	0	0	0	.442	.510	.930	1.440
6	Red Sox	16	9/26/2018	BOS	vs	BAL	W 19-3	45	19	22	9	0	5	19	3	0	7	1	0	48	46	14	0	0	0	1	.489	.521	1.022	1.543
7	Dodgers	16	8/2/2018	LAD	vs	MIL	W 21-5	42	21	18	5	0	7	20	6	1	7	1	0	49	44	12	0	0	0	1	.429	.510	1.048	1.558
8	Dodgers	16	7/2/2018	LAD	vs	PIT	W 17-1	46	17	21	5	0	4	15	6	0	7	0	0	52	38	9	0	0	0	0	.457	.519	.826	1.345
9	Athletics	16	6/1/2018	OAK	@	KCR	W 16-0	41	16	16	1	1	4	16	5	0	11	0	0	47	31	6	0	1	0	1	.390	.447	.756	1.203
10	Orioles	16	5/13/2018	BAL	vs	TBR	W 17-1	44	17	19	3	1	4	17	5	0	5	0	0	49	36	8	0	0	0	0	.432	.490	.818	1.308
11	Dodgers	15	9/30/2018	LAD	@	SFG	W 15-0	40	15	16	5	1	3	14	5	1	6	0	0	47	32	9	0	1	0	2	.400	.468	.800	1.268
12	Indians	15	9/15/2018	CLE	vs	DET	W 15-0	42	15	18	3	1	3	14	6	2	2	0	0	52	32	7	0	2	0	1	.429	.500	.762	1.262
13	Nationals	15	8/26/2018	WSH	@	NYM	W 15-0	42	15	16	3	0	3	15	4	1	10	1	0	47	28	6	0	0	0	1	.381	.447	.667	1.113
14	Indians	15	7/11/2018	CLE	vs	CIN	W 19-4	42	19	19	1	0	4	19	7	0	6	0	0	49	32	5	0	0	0	2	.452	.531	.762	1.293
15	Diamondbacks	15	7/7/2018	ARI	vs	SDP	W 20-5	41	20	18	4	0	5	19	7	1	10	0	0	50	37	9	0	1	0	1	.439	.520	.902	1.422
16	Rockies	14	9/26/2018	COL	vs	PHI	W 14-0	37	14	16	3	2	4	14	4	0	8	0	0	43	35	9	1	1	0	1	.432	.476	.946	1.422
17	Dodgers	14	9/23/2018	LAD	vs	SDP	W 14-0	41	14	16	3	0	3	14	4	0	11	0	0	45	28	6	0	0	0	0	.390	.444	.683	1.127
18	Rangers	14	9/2/2018	TEX	vs	MIN	W 18-4	42	18	19	6	1	6	15	2	3	8	0	0	48	45	13	0	1	0	1	.452	.500	1.071	1.571
19	Astros	14	8/4/2018	HOU	@	LAD	W 14-0	38	14	13	6	0	3	14	5	1	7	1	0	46	28	9	1	1	2	0	.342	.422	.737	1.159
20	Nationals	14	7/7/2018	WSH	vs	MIA	W 18-4	40	18	17	3	0	3	18	4	0	3	0	0	45	29	6	0	1	1	0	.425	.467	.725	1.192
21	Astros	14	5/7/2018	HOU	@	OAK	W 16-2	45	16	20	5	0	3	14	6	0	4	0	0	51	34	8	0	0	0	2	.444	.510	.756	1.265
22	Mariners	13	9/22/2018	SEA	@	TEX	W 13-0	41	13	16	5	1	3	12	6	0	7	0	0	48	32	9	0	1	0	1	.390	.458	.780	1.239
23	Dodgers	13	9/15/2018	LAD	@	STL	W 17-4	41	17	16	1	0	5	16	10	1	9	0	0	52	32	6	0	0	1	2	.390	.519	.780	1.300
24	Mets	13	9/12/2018	NYM	vs	MIA	W 13-0	39	13	14	2	1	3	12	3	0	6	0	0	43	27	6	1	0	0	0	.359	.405	.692	1.097
25	Indians	13	7/21/2018	CLE	@	TEX	W 16-3	47	16	21	8	1	3	15	2	1	3	0	0	50	40	12	0	0	0	0	.447	.480	.851	1.331