highest run differential without making the playoffs ever

The New York Yankees have the highest run differential by a team in the postseason, with a differential of 303 runs.

	TEAM	DIFF	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	303	437	.578	252	184	14,788	1,944	3,668	608	76	477	1,843	1,595	129	2,910	192	105	16,737	5,859	1,161	143	82	144	297	.248	.325	.396	.721
2	Red Sox	90	200	.543	108	91	6,876	910	1,732	330	58	195	853	694	61	1,347	81	43	7,756	2,763	583	79	46	72	153	.252	.324	.402	.726
3	Orioles	75	103	.524	54	49	3,481	408	801	141	7	104	384	332	24	694	29	23	3,883	1,268	252	21	25	34	74	.230	.300	.364	.664
4	Mets	53	105	.562	59	46	3,612	452	854	139	13	100	425	372	41	787	69	19	4,100	1,319	252	43	32	46	65	.236	.312	.365	.677
5	Royals	39	80	.538	43	37	2,701	334	684	116	22	59	320	236	20	525	67	37	3,012	1,021	197	25	30	23	50	.253	.315	.378	.693
6	Phillies	35	137	.504	69	68	4,498	558	1,072	208	25	147	529	471	47	987	91	37	5,098	1,771	380	54	28	63	91	.238	.315	.394	.709
7	Astros	24	161	.516	83	78	5,490	677	1,319	219	13	205	653	568	73	1,244	83	29	6,208	2,179	437	47	30	65	128	.240	.318	.397	.715
8	Diamondbacks	10	57	.491	28	29	1,920	235	476	76	10	65	231	183	21	482	40	13	2,160	767	151	25	11	21	43	.248	.319	.399	.718
9	Cardinals	8	262	.511	134	128	8,675	1,030	2,103	395	53	191	958	743	74	1,705	143	65	9,692	3,177	639	153	47	106	147	.242	.306	.366	.672
10	Braves	8	211	.483	102	109	7,122	829	1,703	280	32	201	795	735	49	1,616	132	57	8,038	2,650	513	86	46	78	128	.239	.313	.372	.685
11	Nationals	6	46	.522	24	22	1,540	173	349	64	4	43	164	162	12	404	26	8	1,743	550	111	18	11	19	22	.227	.303	.357	.660
12	Athletics	1	167	.509	85	82	5,529	599	1,292	249	26	130	556	520	41	1,116	110	52	6,201	1,983	405	86	25	48	92	.234	.303	.359	.662
13	Reds	-2	97	.505	49	48	3,239	346	766	140	27	65	330	274	22	574	86	40	3,601	1,155	232	41	25	46	61	.236	.298	.357	.655
14	Rangers	-3	69	.493	34	35	2,365	301	565	108	6	84	286	220	19	518	39	17	2,632	937	198	16	12	22	52	.239	.307	.396	.704
15	Giants	-8	195	.518	100	93	6,524	727	1,582	246	44	132	674	565	41	1,249	90	82	7,267	2,312	422	106	31	70	105	.242	.306	.354	.660
16	Blue Jays	-9	67	.463	31	36	2,294	284	585	109	12	60	271	209	19	446	60	15	2,555	898	181	11	22	19	51	.255	.320	.391	.711
17	Rays	-16	64	.438	28	36	2,135	253	476	79	8	95	248	184	18	641	39	14	2,349	856	182	5	7	9	43	.223	.289	.401	.690
18	Dodgers	-18	292	.479	140	152	9,681	1,137	2,278	382	55	292	1,088	1,006	81	2,116	181	71	10,924	3,646	729	110	46	104	184	.235	.311	.377	.688
19	Marlins	-20	40	.600	24	16	1,361	163	325	63	5	31	156	147	17	298	18	8	1,549	491	99	18	6	22	31	.239	.319	.361	.680
20	White Sox	-20	62	.484	30	32	2,061	228	508	90	12	42	211	187	34	385	47	34	2,327	748	144	36	9	10	40	.246	.318	.363	.681
21	Rockies	-27	24	.417	10	14	829	90	199	38	5	20	87	70	7	202	9	4	924	307	63	11	7	8	14	.240	.302	.370	.673
22	Tigers	-33	127	.484	61	65	4,252	462	1,005	181	16	101	434	417	41	828	65	38	4,779	1,521	298	56	13	38	93	.236	.310	.358	.667
23	Guardians	-35	128	.500	64	64	4,314	507	995	183	16	127	477	427	48	1,011	90	26	4,856	1,591	326	42	25	38	84	.231	.305	.369	.674
24	Mariners	-39	39	.436	17	22	1,355	151	318	59	4	44	144	133	12	332	26	11	1,521	517	107	14	7	13	22	.235	.307	.382	.689
25	Padres	-40	59	.407	24	35	1,958	223	473	72	8	59	209	174	19	461	22	14	2,183	738	139	13	19	11	38	.242	.307	.377	.684