The Chicago Colts scored their most runs in a game against the Louisville Colonels on June 29, 1897, with 36 runs.
Interpreted as:
highest scoring in a regular-season game games in cubs history| TEAM | R | DATE | TM | OPP | RESULT | AB | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Colts | 36 | 6/29/1897 |  CHI | vs | LOU | W 36-7 | ||||||||||||||||||||||
| 2 | | White Stockings | 35 | 7/24/1882 | CWS | vs | CLE | W 35-4 | ||||||||||||||||||||||
| 3 | | White Stockings | 31 | 7/3/1883 | CWS | vs | BUF | W 31-7 | ||||||||||||||||||||||
| 4 | | White Stockings | 30 | 7/22/1876 | CWS | vs | LOU | W 30-7 | ||||||||||||||||||||||
| 5 | | Colts | 28 | 8/25/1891 | CHI | vs |  BKN | W 28-5 | ||||||||||||||||||||||
| 6 | | Cubs | 26 | 8/18/1995 | CHC | @ |  COL | W 26-7 | 54 | 27 | 7 | 1 | 3 | 26 | 6 | 0 | 8 | 0 | 0 | 60 | 45 | 11 | 0 | 0 | 0 | 1 | .500 | .550 | .833 | 1.383 |
| 7 |  | Cubs | 26 | 8/25/1922 |  CHC | vs |  PHN | W 26-23 | 46 | 25 | 8 | 0 | 3 | 24 | 10 | 1 | 4 | 1 | 0 | 59 | 42 | 11 | 2 | .543 | .632 | .913 | 1.545 | |||
| 8 | | Colts | 26 | 8/1/1894 | CHI | vs |  STL | W 26-8 | ||||||||||||||||||||||
| 9 | | White Stockings | 26 | 9/6/1883 | CWS | vs | DET | W 26-6 | ||||||||||||||||||||||
| 10 |  | Cubs | 24 | 7/3/1945 |  CHC | @ |  BSN | W 24-2 | 53 | 28 | 7 | 0 | 1 | 22 | 8 | 1 | 0 | 0 | 0 | 62 | 38 | 8 | 0 | 0 | .528 | .597 | .717 | 1.314 | ||
| 11 | | Colts | 24 | 5/20/1895 | CHI | vs | PHI | W 24-6 | ||||||||||||||||||||||
| 12 | | Colts | 24 | 7/25/1894 | CHI | vs |  PIT | W 24-6 | ||||||||||||||||||||||
| 13 | | White Stockings | 24 | 7/1/1885 | CWS | vs |  BSN | W 24-10 | ||||||||||||||||||||||
| 14 | | White Stockings | 24 | 9/9/1882 | CWS | vs | TRO | W 24-1 | ||||||||||||||||||||||
| 15 |  | Cubs | 23 | 5/17/1977 |  CHC | vs |  SDP | W 23-6 | 50 | 24 | 4 | 0 | 7 | 22 | 5 | 1 | 0 | 0 | 0 | 57 | 49 | 11 | 1 | 0 | 0 | 1 | .480 | .536 | .980 | 1.516 |
| 16 |  | Cubs | 23 | 4/17/1954 |  CHC | vs | STL | W 23-13 | 44 | 20 | 7 | 0 | 2 | 21 | 12 | 0 | 1 | 0 | 0 | 57 | 33 | 9 | 0 | 1 | 1 | 2 | .455 | .561 | .750 | 1.311 |
| 17 | | White Stockings | 23 | 7/14/1882 | CWS | vs | DET | W 23-4 | ||||||||||||||||||||||
| 18 | | White Stockings | 23 | 8/26/1876 | CWS | vs | STL | W 23-3 | ||||||||||||||||||||||
| 19 | | White Stockings | 23 | 7/25/1876 | CWS | vs | CIN | W 23-3 | ||||||||||||||||||||||
| 20 | | Cubs | 22 | 6/3/1987 | CHC | vs |  HOU | W 22-7 | 44 | 21 | 3 | 0 | 6 | 21 | 9 | 0 | 6 | 1 | 0 | 54 | 42 | 9 | 0 | 1 | 0 | 1 | .477 | .556 | .955 | 1.510 |
| 21 | | Cubs | 22 | 5/17/1979 | CHC | vs |  PHI | L 22-23 | 56 | 26 | 3 | 1 | 6 | 22 | 3 | 0 | 4 | 0 | 0 | 59 | 49 | 10 | 0 | 0 | 0 | 2 | .464 | .492 | .875 | 1.367 |
| 22 |  | Cubs | 22 | 8/13/1937 |  CHC | vs |  CIN | W 22-6 | 46 | 21 | 0 | 2 | 0 | 17 | 9 | 0 | 4 | 0 | 0 | 55 | 25 | 2 | 0 | 0 | .457 | .545 | .543 | 1.089 | ||
| 23 | | White Stockings | 22 | 7/4/1884 | CWS | vs | PHN | W 22-3 | ||||||||||||||||||||||
| 24 | | White Stockings | 22 | 5/30/1883 | CWS | @ | PHN | W 22-4 | ||||||||||||||||||||||
| 25 | | Cubs | 21 | 4/23/2022 | CHC | vs | PIT | W 21-0 | 48 | 23 | 4 | 0 | 1 | 19 | 4 | 1 | 3 | 2 | 0 | 53 | 30 | 5 | 0 | 0 | 0 | 1 | .479 | .528 | .625 | 1.153 |
Results may be incomplete. StatMuse has complete team, game-level data for runs going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
Brewers 
HOU 
CLE 
Mets 
Padres 
Yankees 
Rays 
Tigers 
Mariners 
TOR 
BAL 
SFG 
WSH 
ATH 
MIN 
