14 players are tied for the most runs in a game against the Pirates, with 5 runs. The first three are Jeimer Candelario on April 25, 2018, Tim Raines on August 13, 1987 and Dave Cash on May 27, 1978.

Interpreted as:

highest scoring by a player regular-season games vs pirates

	NAME	R	DATE	TM		OPP	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Jeimer Candelario J. Candelario	5	4/25/2018	DET	@	PIT	6	3	1	0	1	1	0	0	1	0	0	6	7	2	0	0	0	0
2	Tim Raines T. Raines	5	8/13/1987	MON	vs	PIT	2	2	0	0	1	1	3	0	0	2	0	5	5	1	0	0	0	0
3	Dave Cash D. Cash	5	5/27/1978	MON	@	PIT	6	4	1	0	0	1	0	0	0	0	0	6	5	1	0	0	0	0
4	Bill Madlock B. Madlock	5	4/17/1974	CHC	vs	PIT	3	2	1	0	1	2	2	0	0	0	0	5	6	2	0	0	0	0
5	Willie Mays W. Mays	5	9/19/1964	SFG	vs	PIT	3	2	0	0	1	2	2	0	0	1	0	5	5	1	0	0	0	0
6	Wally Post W. Post	5	7/14/1955	CIN	@	PIT	6	4	0	0	2	4	1	0	0	0	0	7	10	2	0	0	0	0
7	Willie Mays W. Mays	5	5/25/1954	NYG	vs	PIT	4	3	0	1	0	1	2	0	0	0	0	6	5	1	0	0	0	0
8	Wally Moon W. Moon	5	5/12/1954	STL	@	PIT	6	5	0	0	1	4	0	0	0	1	0	6	8	1	0	0	0	0
9	Jim Pendleton J. Pendleton	5	8/30/1953	MIL	@	PIT	5	4	0	0	3	5	1	0	0	0	0	6	13	3	0		0	0
10	Solly Hemus S. Hemus	5	5/20/1953	SLN	vs	PIT	2	2	1	1	0	0	3	0	0	0	0	5	5	2	0		0	0
11	Bob Elliott B. Elliott	5	7/21/1951	BSN	vs	PIT	4	4	1	0	1	3	1	0	0	0	0	5	8	2	0		0	0
12	Freddie Lindstrom F. Lindstrom	5	8/24/1929	NYG	vs	PIT	5	4	0	0	1	2	0	0	0	1	0	5	7	1	0
13	Chuck Dressen C. Dressen	5	7/4/1928	CIN	@	PIT	3	3	0	0	0	0	0	1	0	0	0	5	3	0	1
14	John Titus J. Titus	5	6/4/1912	PHN	vs	PIT	4	3	0	2	0	0	1	0	0	0		5	7	2	0
15	Davy Jones D. Jones	5	5/3/1904	CHC	vs	PIT	3	3	2	0	0		2	0	0	0		5	5	2	0
16	Pete Crow-Armstrong P. Crow-Armstrong	4	8/28/2024	CHC	@	PIT	4	4	0	0	0	1	1	0	0	0	0	5	4	0	0	0	1	0
17	Andrew Vaughn A. Vaughn	4	4/8/2023	CWS	@	PIT	3	2	0	0	0	0	2	0	0	0	0	5	2	0	0	0	0	0
18	Tim Anderson T. Anderson	4	4/7/2023	CWS	@	PIT	5	4	2	0	0	0	0	0	0	2	0	5	6	2	0	0	0	0
19	Gleyber Torres G. Torres	4	9/21/2022	NYY	vs	PIT	4	3	0	0	2	5	1	0	0	0	0	5	9	2	0	0	0	0
20	Jake Fraley J. Fraley	4	8/21/2022	CIN	@	PIT	2	2	0	0	1	3	3	0	0	1	0	5	5	1	0	0	0	0
21	Jonathan India J. India	4	9/27/2021	CIN	vs	PIT	5	4	1	0	1	2	0	0	0	1	0	5	8	2	0	0	0	0
22	Paul Goldschmidt P. Goldschmidt	4	5/1/2021	STL	@	PIT	4	3	1	0	0	1	1	0	1	0	0	5	4	1	0	0	0	0
23	Nick Senzel N. Senzel	4	4/6/2021	CIN	vs	PIT	4	3	0	0	0	0	1	0	0	0	0	5	3	0	0	0	0	0
24	Victor Reyes V. Reyes	4	8/7/2020	DET	@	PIT	5	2	0	0	0	1	1	0	0	1	0	6	2	0	0	0	0	0
25	Jon Berti J. Berti	4	9/5/2019	MIA	@	PIT	5	2	1	0	0	0	1	0	1	0	0	6	3	1	0	0	0	0