Mark McGwire has gotten the fewest career hits with 500+ home runs, with 1,626 hits.

Interpreted as:

least hits by a player with 500 or more hr

	NAME	H	HR	G	AB	R	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Mark McGwire M. McGwire	1,626	583	1,874	6,187	1,167	252	6	1,414	1,317	75	1,596	12	8	7,660	3,639	841	3	78	150	147	.263	.394	.588	.982	1480	564.9	.415	157	558.2
2	Harmon Killebrew H. Killebrew	2,086	573	2,435	8,147	1,283	290	24	1,584	1,559	48	1,699	19	18	9,831	4,143	887	0	77	160	243	.256	.376	.509	.884	1630	569	.389	142	477.8
3	Willie McCovey W. McCovey	2,211	521	2,588	8,197	1,229	353	46	1,555	1,345	69	1,550	26	22	9,686	4,219	920	5	70	260	176	.270	.374	.515	.889	1594	551.5	.388	145	497.9
4	Mike Schmidt M. Schmidt	2,234	548	2,404	8,352	1,506	408	59	1,595	1,507	79	1,883	174	92	10,062	4,404	1,015	16	108	201	156	.267	.380	.527	.908	1717	591	.395	147	539.8
5	Eddie Mathews E. Mathews	2,315	512	2,391	8,537	1,509	354	72	1,453	1,444	26	1,487	68	39	10,101	4,349	938	36	58	107	123	.271	.376	.509	.885	1685	557.5	.389	143	531.2
6	Jim Thome J. Thome	2,328	612	2,543	8,422	1,583	451	26	1,699	1,747	69	2,548	19	20	10,313	4,667	1,089	1	74	173	165	.276	.402	.554	.956	1925	653.9	.406	145	589.5
7	Sammy Sosa S. Sosa	2,408	609	2,354	8,813	1,475	379	45	1,667	929	59	2,306	234	107	9,896	4,704	1,033	17	78	154	202	.273	.344	.534	.878	1559	345.1	.370	124	307.3
8	Mickey Mantle M. Mantle	2,415	536	2,401	8,102	1,676	344	72	1,509	1,733	13	1,710	153	38	9,909	4,511	952	14	47	126	113	.298	.421	.557	.977	1941	840	.428	170	821.8
9	Frank Thomas F. Thomas	2,468	521	2,322	8,199	1,494	495	12	1,704	1,667	87	1,397	32	23	10,074	4,550	1,028	0	121	168	226	.301	.419	.555	.974	1954	721.1	.416	154	692
10	David Ortiz D. Ortiz	2,472	541	2,408	8,640	1,419	632	19	1,768	1,319	38	1,750	17	9	10,091	4,765	1,192	2	92	209	236	.286	.380	.552	.931	1760	559.9	.392	140	484.1
11	Manny Ramirez M. Ramirez	2,574	555	2,302	8,244	1,544	547	20	1,831	1,329	109	1,813	38	33	9,774	4,826	1,122	2	90	216	243	.312	.411	.585	.996	1931	719.5	.418	153	658.7
12	Ernie Banks E. Banks	2,583	512	2,528	9,421	1,305	407	90	1,636	763	70	1,236	50	53	10,395	4,706	1,009	45	96	198	229	.274	.330	.500	.830	1496	354.6	.359	118	228.9
13	Reggie Jackson R. Jackson	2,584	563	2,820	9,864	1,551	463	49	1,702	1,375	96	2,597	228	115	11,416	4,834	1,075	13	68	164	183	.262	.356	.490	.846	1749	503	.374	139	497.6
14	Jimmie Foxx J. Foxx	2,646	534	2,317	8,134	1,751	458	125	1,922	1,452	13	1,311	87		9,670	4,956	1,117	71			69	.325	.428	.609	1.038	2135	934.1	.460	158	780.8
15	Ted Williams T. Williams	2,654	521	2,292	7,706	1,798	525	71	1,839	2,021	39	709	24	4	9,791	4,884	1,117	5	20	86	197	.344	.482	.634	1.116	2349	1,219.7	.493	188	1,067
16	Gary Sheffield G. Sheffield	2,689	509	2,576	9,217	1,636	467	27	1,676	1,475	135	1,171	253	104	10,947	4,737	1,003	9	111	130	235	.292	.393	.514	.907	1907	574.5	.391	141	567.2
17	Ken Griffey Jr. K. Griffey Jr.	2,781	630	2,671	9,801	1,662	524	38	1,836	1,312	81	1,779	184	69	11,304	5,271	1,192	8	102	246	199	.284	.370	.538	.907	1892	521.1	.384	132	453.4
18	Babe Ruth B. Ruth	2,873	714	2,503	8,399	2,174	506	136	2,214	2,062	43	1,330	123		10,617	5,793	1,356	113				.342	.474	.690	1.164	2727	1,436.8	.513	197	1,369.6
19	Mel Ott M. Ott	2,876	511	2,730	9,456	1,859	488	72	1,860	1,708	64	896	89		11,337	5,041	1,071	109			38	.304	.414	.533	.947	2204	826.4	.430	156	794.2
20	Barry Bonds B. Bonds	2,935	762	2,986	9,847	2,227	601	77	1,996	2,558	106	1,539	514	141	12,606	5,976	1,440	4	91	688	165	.298	.444	.607	1.051	2663	1,143.3	.435	172	1,142
21	Frank Robinson F. Robinson	2,943	586	2,808	10,006	1,829	528	72	1,812	1,420	198	1,532	204	77	11,743	5,373	1,186	17	102	218	270	.294	.389	.537	.926	2083	807.2	.404	153	717.1
22	Rafael Palmeiro R. Palmeiro	3,020	569	2,831	10,472	1,663	585	38	1,835	1,353	87	1,348	97	40	12,046	5,388	1,192	15	119	172	232	.288	.371	.515	.885	1975	522.8	.380	130	453.5
23	Alex Rodriguez A. Rodriguez	3,115	696	2,784	10,566	2,021	548	31	2,086	1,338	176	2,287	329	76	12,207	5,813	1,275	16	111	97	261	.295	.380	.550	.930	2178	690.1	.395	141	629.5
24	Miguel Cabrera M. Cabrera	3,174	511	2,797	10,356	1,551	627	17	1,881	1,258	74	2,105	40	21	11,796	5,368	1,155	5	103	238	364	.306	.382	.518	.901	1981	585.3	.382	139	547.8
25	Eddie Murray E. Murray	3,255	504	3,026	11,336	1,627	560	35	1,917	1,333	18	1,516	110	43	12,817	5,397	1,099	2	128	222	315	.287	.359	.476	.836	1904	432.6	.365	127	406.9