Since 2017, the Chicago White Sox and the Miami Marlins are tied for the fewest wins, with 529 wins.

Interpreted as:

least total MLB team regular-season wins since 2017

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	White Sox	529	716	.425	1,245	42,153	5,184	10,396	1,976	158	1,331	4,965	3,291	489	11,033	585	200	46,359	16,681	3,465	175	251	96	915	.247	.307	.396	.703
2	Marlins	529	713	.426	1,242	41,971	4,958	10,270	1,894	175	1,192	4,722	3,397	491	10,763	724	244	46,337	16,090	3,261	208	270	171	933	.245	.307	.383	.690
3	Royals	532	715	.427	1,247	42,013	5,193	10,408	2,031	256	1,244	4,955	3,295	434	9,888	943	291	46,269	16,683	3,531	172	355	109	839	.248	.307	.397	.704
4	Tigers	538	706	.432	1,244	41,966	5,066	10,117	1,985	270	1,212	4,851	3,502	397	11,143	527	190	46,254	16,278	3,467	84	305	96	838	.241	.304	.388	.691
5	Pirates	539	707	.433	1,246	41,789	5,053	10,044	1,975	238	1,167	4,816	3,817	462	10,428	641	249	46,587	15,996	3,380	222	297	194	834	.240	.309	.383	.692
6	Orioles	545	700	.438	1,245	42,393	5,489	10,455	2,050	167	1,550	5,263	3,516	486	10,806	607	194	46,808	17,489	3,767	114	299	98	838	.247	.310	.413	.722
7	Rockies	546	700	.438	1,246	42,374	5,722	10,769	2,199	276	1,405	5,493	3,666	393	11,205	575	217	47,001	17,735	3,880	256	312	188	930	.254	.317	.419	.736
8	Rangers	566	681	.454	1,247	42,023	5,643	10,146	1,957	160	1,545	5,359	3,914	491	11,055	824	257	46,846	17,058	3,662	123	295	116	765	.241	.311	.406	.717
9	Angels	569	675	.457	1,244	41,816	5,433	10,054	1,896	167	1,558	5,194	3,903	536	10,627	695	235	46,657	16,958	3,621	113	289	205	909	.240	.311	.406	.717
10	Reds	571	676	.458	1,247	41,712	5,549	10,163	1,961	195	1,512	5,310	4,097	654	10,962	850	287	46,956	17,050	3,668	216	277	152	872	.244	.319	.409	.728
11	Nationals	584	662	.469	1,246	41,987	5,666	10,722	2,155	187	1,359	5,399	3,996	523	9,676	908	280	47,063	17,328	3,701	251	306	234	934	.255	.326	.413	.738
12	Athletics	592	654	.475	1,246	41,746	5,430	9,902	2,078	149	1,557	5,179	4,062	550	10,860	606	174	46,775	16,949	3,784	117	300	104	936	.237	.311	.406	.717
13	Diamondbacks	610	636	.490	1,246	42,178	5,864	10,379	2,181	287	1,441	5,577	4,230	492	10,447	770	188	47,501	17,457	3,909	250	351	194	838	.246	.320	.414	.733
14	Padres	615	629	.494	1,244	41,646	5,382	10,143	1,957	175	1,438	5,135	4,065	419	10,472	763	251	46,675	16,764	3,570	250	295	178	894	.244	.315	.403	.718
15	Blue Jays	619	626	.497	1,245	42,207	5,673	10,543	2,212	118	1,625	5,439	3,981	438	10,105	535	194	47,000	17,866	3,955	99	275	109	959	.250	.319	.423	.742
16	Giants	620	626	.498	1,246	42,133	5,340	10,166	2,079	191	1,337	5,116	3,979	468	10,919	499	184	47,079	16,638	3,607	169	330	208	898	.241	.312	.395	.706
17	Mets	632	614	.507	1,246	41,924	5,609	10,380	2,026	179	1,545	5,392	4,046	706	10,295	585	191	47,134	17,399	3,750	179	279	191	918	.248	.322	.415	.737
18	Phillies	642	603	.516	1,245	42,165	5,755	10,500	2,103	216	1,532	5,513	4,151	462	10,884	760	189	47,250	17,631	3,851	178	294	222	835	.249	.321	.418	.739
19	Mariners	644	601	.517	1,245	41,777	5,495	9,958	1,916	140	1,536	5,265	4,167	651	11,190	787	259	46,987	16,762	3,592	104	288	115	820	.238	.315	.401	.716
20	Cubs	647	600	.519	1,247	41,997	5,889	10,399	2,024	226	1,530	5,615	4,329	632	11,024	741	252	47,480	17,465	3,780	215	307	232	879	.248	.325	.416	.741
21	Twins	649	596	.521	1,245	42,335	5,915	10,603	2,198	168	1,641	5,654	4,093	549	10,664	454	166	47,384	18,060	4,007	97	310	141	853	.250	.322	.427	.749
22	Cardinals	658	586	.529	1,244	41,800	5,643	10,407	2,022	146	1,478	5,387	4,120	571	10,230	687	218	47,045	17,155	3,646	218	336	173	844	.249	.322	.410	.733
23	Red Sox	665	583	.533	1,248	43,192	6,207	11,254	2,553	176	1,521	5,899	4,068	469	10,589	729	225	48,128	18,722	4,250	84	315	230	932	.261	.329	.433	.762
24	Guardians	690	554	.555	1,244	41,869	5,647	10,407	2,143	176	1,404	5,368	3,964	511	9,438	916	243	46,866	17,114	3,723	174	348	226	839	.249	.319	.409	.727
25	Brewers	691	557	.554	1,248	41,864	5,696	10,136	1,960	157	1,567	5,434	4,466	512	11,411	962	247	47,275	17,111	3,684	162	271	208	903	.242	.321	.409	.730