The New York Yankees had the lowest run differential by a team in the 2001 postseason, with a differential of -14 runs.
| TEAM | DIFF | SEASON | G | W% | W | L | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Yankees | -14 | 2001 | 17 | .588 | 10 | 7 | 554 | 57 | 124 | 21 | 1 | 16 | 54 | 50 | 7 | 123 | 8 | 8 | 620 | 195 | 38 | 7 | 2 | 1 | 13 | .224 | .295 | .352 | .647 |
| 2 |  | Mariners | -13 | 2001 | 10 | .400 | 4 | 6 | 329 | 38 | 75 | 12 | 2 | 9 | 36 | 36 | 2 | 83 | 6 | 3 | 371 | 118 | 23 | 3 | 1 | 3 | 7 | .228 | .307 | .359 | .666 |
| 3 |  | Astros | -8 | 2001 | 3 | .000 | 0 | 3 | 95 | 6 | 19 | 2 | 0 | 3 | 6 | 8 | 0 | 16 | 0 | 1 | 103 | 30 | 5 | 0 | 0 | 0 | 5 | .200 | .262 | .316 | .578 |
| 4 |  | Athletics | -6 | 2001 | 5 | .400 | 2 | 3 | 174 | 12 | 43 | 13 | 1 | 4 | 11 | 11 | 3 | 31 | 3 | 0 | 190 | 70 | 18 | 0 | 2 | 1 | 3 | .247 | .300 | .402 | .702 |
| 5 |  | Braves | 1 | 2001 | 8 | .500 | 4 | 4 | 268 | 29 | 65 | 12 | 0 | 11 | 27 | 15 | 1 | 57 | 1 | 4 | 286 | 110 | 23 | 1 | 1 | 1 | 6 | .243 | .284 | .410 | .695 |
| 6 |  | Cardinals | 2 | 2001 | 5 | .400 | 2 | 3 | 152 | 12 | 29 | 3 | 0 | 6 | 12 | 12 | 1 | 38 | 3 | 0 | 174 | 50 | 9 | 8 | 1 | 0 | 4 | .191 | .253 | .329 | .582 |
| 7 |  | Indians | 10 | 2001 | 5 | .400 | 2 | 3 | 173 | 26 | 45 | 9 | 1 | 5 | 25 | 13 | 1 | 43 | 1 | 0 | 188 | 71 | 15 | 0 | 1 | 0 | 5 | .260 | .314 | .410 | .724 |
| 8 |  | Diamondbacks | 28 | 2001 | 17 | .647 | 11 | 6 | 574 | 69 | 142 | 25 | 0 | 11 | 67 | 53 | 8 | 131 | 6 | 5 | 650 | 200 | 36 | 13 | 2 | 13 | 14 | .247 | .319 | .348 | .667 |
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