lowest run differential with more than 20 runs in game since 2016

Since 2016, the Miami Marlins have the lowest run differential by a team in a game with more than 20 runs, with a differential of 12 runs against the Rangers on July 26, 2017.

Interpreted as:

lowest run differential with more than 20 runs in regular-season game since 2016

	TEAM	DIFF	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Marlins	12	22	7/26/2017	MIA	@	TEX	W 22-10	47	22	8	2	4	21	6	0	11	0	54	46	14	0	1	0	1	.468	.519	.979	1.497
2	Athletics	14	21	9/10/2019	OAK	@	HOU	W 21-7	51	25	3	0	6	21	4	0	7	0	56	46	9	0	1	0	0	.490	.518	.902	1.420
3	Blue Jays	15	22	9/12/2021	TOR	@	BAL	W 22-7	45	19	5	0	5	22	8	2	8	0	55	39	10	0	0	0	0	.422	.527	.867	1.394
4	Astros	16	21	8/18/2022	HOU	@	CWS	W 21-5	51	25	5	0	4	21	4	0	9	1	55	42	9	0	0	0	1	.490	.527	.824	1.351
5	Padres	16	24	7/16/2021	SDP	@	WSH	W 24-8	50	22	3	1	5	23	9	0	7	3	60	42	9	1	0	0	0	.440	.525	.840	1.365
6	Dodgers	16	21	8/2/2018	LAD	vs	MIL	W 21-5	42	18	5	0	7	20	6	1	7	1	49	44	12	0	0	0	1	.429	.510	1.048	1.558
7	Braves	18	21	8/12/2023	ATL	@	NYM	W 21-3	48	22	5	0	6	21	6	1	8	3	55	45	11	0	0	0	0	.458	.527	.938	1.465
8	Giants	18	23	9/1/2020	SFG	@	COL	W 23-5	52	27	8	1	4	23	5	1	6	1	59	49	13	0	1	0	0	.519	.559	.942	1.502
9	Athletics	18	21	9/20/2018	OAK	vs	LAA	W 21-3	44	22	4	0	3	20	7	0	7	0	51	35	7	0	0	0	2	.500	.569	.795	1.364
10	Nationals	18	23	4/30/2017	WSH	vs	NYM	W 23-5	46	23	4	0	7	23	6	0	6	0	54	48	11	1	1	3	0	.500	.547	1.043	1.591
11	Angels	19	21	7/2/2016	LAA	@	BOS	W 21-2	50	22	6	1	4	19	3	1	5	0	55	42	11	0	1	0	0	.440	.473	.840	1.313
12	Braves	20	29	9/9/2020	ATL	vs	MIA	W 29-9	47	23	2	0	7	28	9	1	9	2	58	46	9	0	1	0	0	.489	.569	.979	1.548
13	Astros	20	21	9/8/2019	HOU	vs	SEA	W 21-1	47	22	11	0	2	19	7	1	8	0	55	39	13	0	0	0	0	.468	.545	.830	1.375
14	Mets	20	24	8/16/2018	NYM	@	PHI	W 24-4	52	25	7	1	3	19	7	1	5	1	61	43	11	1	0	1	2	.481	.550	.827	1.377
15	Padres	21	21	5/10/2025	SDP	@	COL	W 21-0	50	24	4	1	5	20	5	0	4	0	56	45	10	0	1	0	0	.480	.518	.900	1.418
16	Cubs	21	21	4/23/2022	CHC	vs	PIT	W 21-0	48	23	4	0	1	19	4	1	3	2	53	30	5	0	0	0	1	.479	.528	.625	1.153
17	Dodgers	21	22	7/10/2021	LAD	vs	ARI	W 22-1	44	21	2	1	8	22	8	1	4	0	53	49	11	0	0	0	2	.477	.566	1.114	1.680
18	Astros	21	23	8/10/2019	HOU	@	BAL	W 23-2	50	25	7	0	6	21	2	0	4	0	52	50	13	0	0	0	3	.500	.519	1.000	1.519
19	Nationals	21	25	7/31/2018	WSH	vs	NYM	W 25-4	50	26	5	2	5	25	8	1	6	2	59	50	12	0	0	1	0	.520	.593	1.000	1.593
20	Reds	22	24	4/20/2025	CIN	@	BAL	W 24-2	51	25	4	1	3	23	11	2	6	1	64	40	8	0	0	0	1	.490	.594	.784	1.378
21	Blue Jays	23	28	7/22/2022	TOR	@	BOS	W 28-5	57	29	5	0	5	28	5	1	9	0	63	49	10	0	0	0	0	.509	.556	.860	1.415
22	Angels	24	25	6/24/2023	LAA	@	COL	W 25-1	52	28	5	0	5	25	6	1	3	0	59	48	10	0	0	0	3	.538	.593	.923	1.516