Lucas Giolito is 3-6 with an ERA of 5.31 and 48 strikeouts in 10 appearances against the Astros in his career.
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. Giolito | 9/19/2017 | @ | L | 1 | 2.70 | 3 | 0 | 0 | 0 | 6.2 | 7 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 26 | 1 | ||
| 2 | | L. Giolito | 4/21/2018 | vs | L | 1 | 40.50 | 1 | 0 | 0 | 0 | 2.0 | 5 | 9 | 9 | 1 | 7 | 0 | 0 | 0 | 18 | 0 | ||
| 3 | | L. Giolito | 7/8/2018 | @ | L | 1 | 2.45 | 3 | 0 | 0 | 0 | 7.1 | 3 | 2 | 2 | 1 | 3 | 1 | 0 | 0 | 28 | 0 | ||
| 4 | | L. Giolito | 5/23/2019 | @ | W | 1 | 0.00 | 9 | 1 | 1 | 0 | 9.0 | 4 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 32 | 0 | ||
| 5 | | L. Giolito | 7/17/2021 | vs | W | 1 | 1.00 | 8 | 1 | 0 | 0 | 9.0 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 30 | 0 | ||
| 6 | | L. Giolito | 6/17/2022 | @ | L | 1 | 14.40 | 3 | 0 | 0 | 0 | 5.0 | 7 | 8 | 8 | 2 | 3 | 1 | 0 | 0 | 25 | 0 | ||
| 7 | | L. Giolito | 8/18/2022 | vs | L | 1 | 21.00 | 5 | 0 | 0 | 0 | 3.0 | 8 | 7 | 7 | 1 | 1 | 0 | 0 | 0 | 18 | 0 | ||
| 8 | | L. Giolito | 4/1/2023 | @ | 1 | 3.60 | 6 | 0 | 0 | 0 | 5.0 | 5 | 2 | 3 | 0 | 1 | 1 | 0 | 0 | 23 | 0 | |||
| 9 | | L. Giolito | 5/14/2023 | vs | L | 1 | 6.00 | 6 | 0 | 0 | 0 | 6.0 | 7 | 4 | 4 | 1 | 0 | 0 | 0 | 0 | 24 | 0 | ||
| 10 | | L. Giolito | 8/3/2025 | vs | W | 1 | 1.13 | 4 | 0 | 0 | 0 | 8.0 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 28 | 0 | ||
| Total | 10 | 5.31 | 48 | 2 | 1 | 0 | 61.0 | 52 | 36 | 37 | 9 | 18 | 4 | 0 | 0 | 252 | 1 |
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