Luis Castillo has a 2-2 record with an ERA of 3.42 and 44 strikeouts in 8 appearances against the Astros in his career.
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. Castillo | 6/17/2019 |  CIN | vs |  HOU | W | 1 | 3.00 | 7 | 0 | 0 | 0 | 6.0 | 2 | 2 | 2 | 0 | 6 | 0 | 0 | 0 | 25 | 1 |
| 2 |  | L. Castillo | 5/5/2023 |  SEA | vs | HOU | 1 | 5.14 | 5 | 0 | 0 | 0 | 7.0 | 5 | 4 | 4 | 1 | 1 | 0 | 0 | 0 | 26 | 0 | |
| 3 | | L. Castillo | 7/7/2023 | SEA | @ | HOU | W | 1 | 0.00 | 3 | 0 | 0 | 0 | 7.0 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 27 | 0 |
| 4 | | L. Castillo | 9/25/2023 | SEA | vs | HOU | L | 1 | 7.50 | 8 | 0 | 0 | 0 | 6.0 | 8 | 5 | 5 | 2 | 1 | 0 | 0 | 0 | 26 | 0 |
| 5 | | L. Castillo | 5/28/2024 | SEA | vs | HOU | 1 | 3.00 | 6 | 0 | 0 | 0 | 6.0 | 5 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 24 | 0 | |
| 6 | | L. Castillo | 7/19/2024 | SEA | vs | HOU | L | 1 | 3.86 | 3 | 0 | 0 | 0 | 7.0 | 6 | 3 | 3 | 0 | 1 | 1 | 0 | 0 | 28 | 0 |
| 7 | | L. Castillo | 4/8/2025 | SEA | vs | HOU | 1 | 0.00 | 6 | 0 | 0 | 0 | 5.0 | 5 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 21 | 0 | |
| 8 | | L. Castillo | 5/25/2025 | SEA | @ | HOU | 1 | 4.50 | 6 | 0 | 0 | 0 | 6.0 | 9 | 3 | 3 | 0 | 1 | 0 | 0 | 0 | 27 | 0 | |
| Total | 8 | 3.42 | 44 | 0 | 0 | 0 | 50.0 | 45 | 19 | 20 | 4 | 13 | 1 | 0 | 0 | 204 | 1 |
Some of the information used here was obtained free of charge from Retrosheet.
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