Luis Castillo has a 1-5 record with an ERA of 4.75 and 57 strikeouts in 10 appearances against the Guardians in his career.
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. Castillo | 6/11/2019 |  CIN | @ |  CLE | 1 | 1.50 | 6 | 0 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 24 | 1 | |
| 2 | | L. Castillo | 8/6/2020 | CIN | @ | CLE | L | 1 | 5.40 | 9 | 0 | 0 | 0 | 5.0 | 4 | 3 | 3 | 1 | 4 | 0 | 0 | 0 | 23 | 0 |
| 3 | | L. Castillo | 5/8/2021 | CIN | @ | CLE | L | 1 | 9.00 | 2 | 0 | 0 | 0 | 4.0 | 5 | 4 | 6 | 0 | 2 | 0 | 0 | 0 | 21 | 0 |
| 4 | | L. Castillo | 8/9/2021 | CIN | @ | CLE | L | 1 | 21.60 | 2 | 0 | 0 | 0 | 3.1 | 7 | 8 | 8 | 2 | 3 | 1 | 0 | 0 | 21 | 0 |
| 5 |  | L. Castillo | 8/27/2022 |  SEA | vs |  CLE | 1 | 1.50 | 10 | 0 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 24 | 0 | |
| 6 | | L. Castillo | 9/2/2022 | SEA | @ | CLE | W | 1 | 0.00 | 4 | 0 | 0 | 0 | 6.0 | 5 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 24 | 0 |
| 7 | | L. Castillo | 3/30/2023 | SEA | vs | CLE | 1 | 0.00 | 6 | 0 | 0 | 0 | 6.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19 | 0 | |
| 8 | | L. Castillo | 4/2/2024 | SEA | vs | CLE | L | 1 | 6.35 | 7 | 0 | 0 | 0 | 5.2 | 10 | 4 | 4 | 1 | 1 | 0 | 0 | 1 | 27 | 0 |
| 9 | | L. Castillo | 6/20/2024 | SEA | @ | CLE | L | 1 | 9.00 | 4 | 0 | 0 | 0 | 5.0 | 8 | 5 | 5 | 2 | 2 | 0 | 0 | 0 | 23 | 0 |
| 10 | | L. Castillo | 6/13/2025 | SEA | vs | CLE | 1 | 3.00 | 7 | 0 | 0 | 0 | 6.0 | 3 | 2 | 2 | 2 | 3 | 0 | 0 | 0 | 23 | 0 | |
| Total | 10 | 4.75 | 57 | 0 | 0 | 0 | 53.0 | 51 | 28 | 30 | 10 | 19 | 2 | 0 | 1 | 229 | 1 |
Some of the information used here was obtained free of charge from Retrosheet.
Astros 
Angels 
Rangers 
Athletics 
MIN 
Yankees 
Rays 
Tigers 
Phillies 
Mets 
Cubs 
Brewers 
Dodgers 
Giants 
MIA 
PIT 
WSH 
TOR 
STL 
ATL 
KCR 
