Marcus Semien had his most strikeouts in a game on August 20 and on May 13, 2014, with 4 strikeouts.
Interpreted as:
marcus most strikeouts in a regular-season game| NAME | SO | DATE | TM | OPP | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Semien | 4 | 8/20/2024 |  TEX | vs |  PIT | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 |  | M. Semien | 4 | 5/13/2014 |  CWS | @ |  OAK | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | M. Semien | 3 | 9/13/2024 | TEX | @ |  SEA | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | | M. Semien | 3 | 8/29/2024 | TEX | @ | CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | M. Semien | 3 | 7/2/2024 | TEX | vs |  SDP | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 0 |
| 6 | | M. Semien | 3 | 8/26/2022 | TEX | vs |  DET | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | M. Semien | 3 | 6/22/2022 | TEX | vs |  PHI | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | M. Semien | 3 | 6/1/2022 | TEX | vs |  TBR | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 |  | M. Stroman | 3 | 9/9/2021 |  NYM | @ |  MIA | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 |  | M. Semien | 3 | 6/18/2021 |  TOR | @ |  BAL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | | M. Semien | 3 | 5/25/2021 | TOR | @ |  NYY | 5 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 0 | 0 | 0 | 0 |
| 12 | | M. Semien | 3 | 4/10/2021 | TOR | vs |  LAA | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 |  | M. Semien | 3 | 9/9/2020 | OAK | vs |  HOU | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | | M. Semien | 3 | 8/5/2020 | OAK | vs | TEX | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 |
| 15 | | M. Semien | 3 | 8/1/2020 | OAK | @ | SEA | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | M. Semien | 3 | 9/15/2019 | OAK | @ | TEX | 4 | 1 | 1 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 5 | 4 | 1 | 0 | 0 | 0 | 0 |
| 17 | | M. Semien | 3 | 9/26/2018 | OAK | @ | SEA | 5 | 2 | 2 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5 | 5 | 1 | 0 | 0 | 0 | 0 |
| 18 | | M. Semien | 3 | 8/18/2018 | OAK | vs | HOU | 5 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 0 |
| 19 | | M. Semien | 3 | 8/15/2018 | OAK | vs | SEA | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 0 |
| 20 | | M. Semien | 3 | 4/14/2018 | OAK | @ | SEA | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 2 | 1 | 0 | 0 | 0 | 0 |
| 21 | | M. Semien | 3 | 4/3/2018 | OAK | vs | TEX | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 0 |
| 22 | | M. Semien | 3 | 9/4/2017 | OAK | vs | LAA | 6 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 0 |
| 23 | | M. Semien | 3 | 8/6/2017 | OAK | @ | LAA | 6 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 0 | 0 | 0 | 0 |
| 24 | | M. Semien | 3 | 7/30/2017 | OAK | vs |  MIN | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 |  | M. Stroman | 3 | 5/24/2017 | TOR | @ |  MIL | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.
Some of the information used here was obtained free of charge from Retrosheet.
Red Sox 
Cubs 
Cardinals 
Dodgers 
KCR 
CIN 
MIL 
