Mitch Keller has a 37-60 record with an ERA of 4.52 and 760 strikeouts in 149 appearances for the Pirates in his career.
| NAME | SEASON | TM | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Keller | 2019 |  PIT | 11 | 1 | 5 | .167 | 11 | 7.13 | 65 | 0 | 0 | 0 | 48.0 | 72 | 38 | 41 | 6 | 16 | 1 | 0 | 0 | 227 | 2 | 12.19 | 3.00 | 4.06 | 1.13 | 28.6 | 7.0 | 1.83 | .475 | 7.69 | 164 | 3.18 | 72 | 13.50 | 6.6 |
| 2 | | M. Keller | 2020 | PIT | 5 | 1 | 1 | .500 | 5 | 2.91 | 16 | 0 | 0 | 0 | 21.2 | 9 | 7 | 7 | 4 | 18 | 1 | 0 | 0 | 87 | 2 | 6.65 | 7.48 | 0.89 | 1.66 | 18.4 | 20.7 | 1.25 | .104 | 2.91 | 65 | 6.74 | 150 | 3.74 | -5.3 |
| 3 | | M. Keller | 2021 | PIT | 23 | 5 | 11 | .313 | 23 | 6.17 | 92 | 0 | 0 | 0 | 100.2 | 131 | 69 | 69 | 10 | 49 | 7 | 0 | 1 | 470 | 2 | 8.23 | 4.38 | 1.88 | 0.89 | 19.6 | 10.4 | 1.79 | .388 | 6.17 | 146 | 4.29 | 101 | 11.71 | -0.6 |
| 4 | | M. Keller | 2022 | PIT | 31 | 5 | 12 | .294 | 29 | 3.91 | 138 | 0 | 0 | 0 | 159.0 | 162 | 69 | 77 | 14 | 60 | 12 | 0 | 1 | 687 | 2 | 7.81 | 3.40 | 2.30 | 0.79 | 20.1 | 8.7 | 1.40 | .320 | 4.36 | 96 | 3.87 | 97 | 9.17 | 2 |
| 5 | | M. Keller | 2023 | PIT | 32 | 13 | 9 | .591 | 32 | 4.21 | 210 | 1 | 1 | 0 | 194.1 | 187 | 91 | 97 | 25 | 55 | 12 | 0 | 0 | 825 | 5 | 9.73 | 2.55 | 3.82 | 1.16 | 25.5 | 6.7 | 1.25 | .310 | 4.49 | 94 | 3.80 | 87 | 8.66 | 12.5 |
| 6 | | M. Keller | 2024 | PIT | 31 | 11 | 12 | .478 | 31 | 4.25 | 166 | 1 | 0 | 0 | 178.0 | 182 | 84 | 90 | 23 | 50 | 15 | 0 | 0 | 773 | 1 | 8.39 | 2.53 | 3.32 | 1.16 | 21.5 | 6.5 | 1.30 | .306 | 4.55 | 101 | 4.07 | 100 | 9.20 | -0.2 |
| 7 | | M. Keller | 2025 | PIT | 16 | 1 | 10 | .091 | 16 | 4.02 | 73 | 0 | 0 | 0 | 94.0 | 91 | 42 | 46 | 6 | 24 | 4 | 0 | 0 | 395 | 2 | 6.99 | 2.30 | 3.04 | 0.57 | 18.5 | 6.1 | 1.22 | .295 | 4.40 | 96 | 3.24 | 80 | 8.71 | 8.2 |
| Total | 149 | 37 | 60 | .381 | 147 | 4.52 | 760 | 2 | 1 | 0 | 795.2 | 834 | 400 | 427 | 88 | 272 | 52 | 0 | 2 | 3,464 | 16 | 8.60 | 3.08 | 2.79 | 1.00 | 21.9 | 7.9 | 1.39 | .325 | 4.83 | 106 | 3.91 | 94 | 9.43 | 23.1 |
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