The Milwaukee Brewers had the highest run differential by a team in 1982, with a differential of 174 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Brewers	174	1982	163	.586	95	67	5,733	891	1,599	277	41	216	843	484	18	714	84	52	6,337	2,606	534	56	46	42	106	.279	.335	.455	.789
2	Angels	144	1982	162	.574	93	69	5,532	814	1,518	268	26	186	760	613	35	760	55	53	6,350	2,396	480	114	56	46	130	.274	.347	.433	.780
3	Orioles	87	1982	163	.580	94	68	5,557	774	1,478	259	27	179	735	634	25	796	49	38	6,325	2,328	465	57	52	52	141	.266	.341	.419	.760
4	Expos	81	1982	162	.531	86	76	5,557	697	1,454	270	38	133	656	503	35	816	156	56	6,221	2,199	441	85	41	72	107	.262	.325	.396	.720
5	Dodgers	79	1982	162	.543	88	74	5,642	691	1,487	222	32	138	661	528	30	804	151	56	6,361	2,187	392	106	55	83	98	.264	.327	.388	.715
6	Cardinals	76	1982	162	.568	92	70	5,455	685	1,439	239	52	67	632	569	30	805	200	91	6,196	1,983	358	87	55	66	110	.264	.334	.364	.697
7	White Sox	76	1982	162	.537	87	75	5,575	786	1,523	266	52	136	747	533	30	866	136	58	6,242	2,301	454	54	50	45	117	.273	.337	.413	.750
8	Royals	67	1982	162	.556	90	72	5,629	784	1,603	295	58	132	746	442	25	758	133	48	6,177	2,410	485	32	49	37	140	.285	.337	.428	.765
9	Tigers	44	1982	162	.512	83	79	5,590	729	1,489	237	40	177	684	470	26	807	93	66	6,166	2,337	454	41	39	29	99	.266	.324	.418	.742
10	Red Sox	40	1982	162	.549	89	73	5,596	753	1,536	271	31	136	705	547	28	736	42	39	6,262	2,277	438	53	38	34	171	.274	.340	.407	.747
11	Braves	37	1982	162	.549	89	73	5,507	739	1,411	215	22	146	687	554	29	869	151	77	6,229	2,108	383	96	43	64	102	.256	.325	.383	.708
12	Pirates	28	1982	162	.519	84	78	5,614	724	1,535	272	40	134	688	447	28	862	161	75	6,234	2,289	446	78	67	72	116	.273	.327	.408	.734
13	Padres	17	1982	162	.500	81	81	5,575	675	1,435	217	52	81	611	429	22	877	165	77	6,159	1,999	350	86	47	78	96	.257	.311	.359	.669
14	Phillies	10	1982	162	.549	89	73	5,454	664	1,417	245	25	112	624	506	24	831	128	76	6,107	2,048	382	85	38	66	134	.260	.323	.376	.699
15	Yankees	-7	1982	162	.488	79	83	5,526	709	1,417	225	37	161	666	590	24	719	69	45	6,244	2,199	423	55	49	45	152	.256	.328	.398	.726
16	Giants	-14	1982	162	.537	87	75	5,499	673	1,393	213	30	133	631	607	17	915	130	56	6,227	2,065	376	59	45	70	131	.253	.327	.376	.703
17	Cubs	-33	1982	162	.451	73	89	5,531	676	1,436	239	46	102	647	460	25	869	132	70	6,141	2,073	387	76	49	62	97	.260	.317	.375	.692
18	Blue Jays	-50	1982	162	.481	78	84	5,526	651	1,447	262	45	106	605	415	28	749	118	81	6,067	2,117	413	48	50	38	107	.262	.314	.383	.697
19	Astros	-51	1982	162	.475	77	85	5,440	569	1,342	236	48	74	533	435	19	830	140	61	6,008	1,896	358	68	46	67	104	.247	.302	.349	.651
20	Mariners	-61	1982	162	.469	76	86	5,626	651	1,431	259	33	130	614	456	22	806	131	82	6,181	2,146	422	42	35	31	113	.254	.311	.381	.692
21	Indians	-65	1982	162	.481	78	84	5,559	683	1,458	225	32	109	639	651	35	625	151	68	6,359	2,074	366	74	40	48	143	.262	.341	.373	.714
22	Mets	-114	1982	162	.401	65	97	5,510	609	1,361	227	26	97	568	456	25	1,005	137	58	6,108	1,931	350	64	53	49	112	.247	.305	.350	.655
23	Reds	-116	1982	162	.377	61	101	5,479	545	1,375	228	34	82	496	470	21	817	131	69	6,099	1,917	344	88	41	50	143	.251	.310	.350	.660
24	Athletics	-128	1982	162	.420	68	94	5,448	691	1,286	211	27	149	659	582	20	948	232	87	6,154	1,998	387	50	54	20	95	.236	.309	.367	.676
25	Rangers	-159	1982	162	.395	64	98	5,445	590	1,354	204	26	115	558	447	32	750	63	45	6,020	1,955	345	64	32	22	134	.249	.308	.359	.667