| TEAM | OPPONENT | DATE | TIME (ET) | SPREAD | OVER/UNDER | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | St. Louis Cardinals | +146 | @ |  Chicago Cubs | -175 | Fri, Sep 26, 2025 | 2:20 PM | +1.5 | 9.0 |
| 2 |  | Minnesota Twins | +141 | @ |  Philadelphia Phillies | -168 | Fri, Sep 26, 2025 | 6:45 PM | +1.5 | 8.5 |
| 3 |  | Chicago White Sox | +110 | @ |  Washington Nationals | -131 | Fri, Sep 26, 2025 | 6:45 PM | +1.5 | 8.5 |
| 4 |  | Baltimore Orioles | +125 | @ |  New York Yankees | -150 | Fri, Sep 26, 2025 | 7:05 PM | +1.5 | 8.5 |
| 5 |  | Tampa Bay Rays | +153 | @ |  Toronto Blue Jays | -185 | Fri, Sep 26, 2025 | 7:07 PM | +1.5 | 8.0 |
| 6 |  | Texas Rangers | +129 | @ |  Cleveland Guardians | -155 | Fri, Sep 26, 2025 | 7:10 PM | +1.5 | 7.5 |
| 7 |  | Detroit Tigers | +104 | @ |  Boston Red Sox | -124 | Fri, Sep 26, 2025 | 7:10 PM | +1.5 | 8.5 |
| 8 |  | New York Mets | -135 | @ |  Miami Marlins | +113 | Fri, Sep 26, 2025 | 7:10 PM | -1.5 | 8.5 |
| 9 |  | Pittsburgh Pirates | +136 | @ |  Atlanta Braves | -163 | Fri, Sep 26, 2025 | 7:15 PM | +1.5 | 8.5 |
| 10 |  | Cincinnati Reds | +140 | @ |  Milwaukee Brewers | -168 | Fri, Sep 26, 2025 | 8:10 PM | +1.5 | 8.0 |
| 11 |  | Houston Astros | -148 | @ |  Los Angeles Angels | +124 | Fri, Sep 26, 2025 | 9:38 PM | -1.5 | 9.0 |
| 12 |  | Arizona Diamondbacks | +122 | @ |  San Diego Padres | -147 | Fri, Sep 26, 2025 | 9:40 PM | +1.5 | 7.5 |
| 13 |  | Los Angeles Dodgers | +110 | @ |  Seattle Mariners | -131 | Fri, Sep 26, 2025 | 9:40 PM | +1.5 | 7.0 |
| 14 |  | Colorado Rockies | +194 | @ |  San Francisco Giants | -239 | Fri, Sep 26, 2025 | 10:15 PM | +1.5 | 8.0 |
Betting lines shown represent consensus, closing odds.
Reds 
Cardinals 
Pirates 
Mets 
Dodgers 
Tigers 
Astros 
KCR 
TBR 
CWS 
MIN 
BAL 
