Walter Johnson has the most career starts versus the Red Sox, with 91 starts.

Interpreted as:

MLB most regular-season games started by a player vs red sox

	NAME	GS	G	W	L	W%	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Walter Johnson W. Johnson	91	112	53	43	.552	1.62	488	75	15	6	815.0	670		233	6	180	31	20			12	5.39	1.99	2.71	0.07		5.6	1.04	.262	2.57	7.40
2	Early Wynn E. Wynn	84	97	39	33	.542	3.90	376	40	7	3	630.0	620	273	310	58	274	9	11	10	2,750	13	5.37	3.91	1.37	0.83	13.7	10.0	1.42	.276	4.43	8.86
3	Eddie Plank E. Plank	82	94	49	31	.613	1.25	339	65	8	2	691.0	596		230	10	154	30	11			15	4.42	2.01	2.20	0.13		5.8	1.09	.277	3.00	7.76
4	Mel Harder M. Harder	79	96	44	30	.595	3.62	234	35	6	3	594.2	659	239	289	31	178	6	13		2,575	3	3.54	2.69	1.31	0.47	9.1	6.9	1.41	.295	4.37	9.97
5	Bob Feller B. Feller	68	84	33	27	.550	4.11	370	31	4	2	519.0	481	237	257	39	276	3	9	3	2,253	7	6.42	4.79	1.34	0.68	16.4	12.3	1.46	.282	4.46	8.34
6	Ted Lyons T. Lyons	68	80	39	28	.582	2.96	152	58	6	3	603.0	586	198	234	20	141	2	10		2,500	9	2.27	2.10	1.08	0.30	6.1	5.6	1.21	.259	3.49	8.75
7	Red Faber R. Faber	67	99	36	30	.545	2.93	187	38	3	6	565.0	562		251	4	155	11	26			6	2.98	2.47	1.21	0.06		6.5	1.27	.274	4.00	8.95
8	Bobo Newsom B. Newsom	62	79	23	28	.451	4.24	224	29	7	5	456.2	483	215	249	31	233	9	9		2,043	12	4.41	4.59	0.96	0.61	11.0	11.4	1.57	.292	4.91	9.52
9	Hooks Dauss H. Dauss	61	83	36	23	.610	2.80	184	40	8	8	534.0	506		220	10	183	23	17			3	3.10	3.08	1.01	0.17		8.1	1.29	.266	3.71	8.53
10	Mike Mussina M. Mussina	57	57	21	17	.553	3.66	314	5	2	0	376.2	363	153	165	41	99	11	0	6	1,545	5	7.50	2.37	3.17	0.98	20.3	6.4	1.23	.298	3.94	8.67
11	Jim Palmer J. Palmer	57	59	22	16	.579	2.98	277	26	5	0	429.0	386	142	155	43	160	2	1	4	1,787	12	5.81	3.36	1.73	0.90	15.5	9.0	1.27	.263	3.25	8.10
12	Virgil Trucks V. Trucks	57	80	19	29	.396	4.00	242	15	3	4	423.1	422	188	213	40	191	9	14	2	1,863	11	5.14	4.06	1.27	0.85	13.0	10.3	1.45	.277	4.53	8.97
13	Jim Perry J. Perry	54	76	34	21	.618	3.39	192	17	6	2	424.1	412	160	185	47	149	5	10	14	1,806	7	4.07	3.16	1.29	1.00	10.6	8.3	1.32	.258	3.92	8.74
14	Stan Coveleski S. Coveleski	54	59	38	15	.717	2.32	103	35	10	1	442.2	407	114	134	2	118	6	4		1,818	6	2.09	2.40	0.87	0.04	5.7	6.5	1.19	.255	2.72	8.27
15	Red Ruffing R. Ruffing	53	55	29	16	.644	3.39	221	37	7	1	422.1	390	159	184	37	138	5	2		1,756	4	4.71	2.94	1.60	0.79	12.6	7.9	1.25	.261	3.92	8.31
16	George Mullin G. Mullin	53	62	25	30	.455	1.01	173	43	2	0	454.2	475		233	9	173	18	8			12	3.42	3.42	1.00	0.18		9.5	1.43	.322	4.61	9.40
17	Bob Lemon B. Lemon	52	65	31	17	.646	3.44	178	29	2	4	432.0	392	165	190	24	226	9	6		1,873	15	3.71	4.71	0.79	0.50	9.5	12.1	1.43	.256	3.96	8.17
18	Tommy Bridges T. Bridges	52	61	28	23	.549	3.99	219	26	3	1	397.0	405	176	211	27	195	3	8		1,760	8	4.96	4.42	1.12	0.61	12.4	11.1	1.51	.287	4.78	9.18
19	Willis Hudlin W. Hudlin	52	73	27	26	.509	3.88	105	29	1	3	435.2	485	188	223	15	117	8	11		1,882	4	2.17	2.42	0.90	0.31	5.6	6.2	1.38	.287	4.61	10.02
20	Jim Kaat J. Kaat	51	59	24	15	.615	3.92	201	14	1	1	351.0	360	153	167	36	94	11	3	2	1,485	10	5.15	2.41	2.14	0.92	13.5	6.3	1.29	.283	4.28	9.23
21	Bob Shawkey B. Shawkey	51	73	32	23	.582	2.35	222	34	5	5	467.0	408	122	164	9	151	5	18		1,916	9	4.28	2.91	1.47	0.17	11.6	7.9	1.20	.261	3.16	7.86
22	Billy Pierce B. Pierce	49	64	24	16	.600	3.57	247	22	6	2	383.1	327	152	166	35	198	4	10		1,649	8	5.80	4.65	1.25	0.82	15.0	12.0	1.37	.251	3.90	7.68
23	Earl Whitehill E. Whitehill	49	54	30	11	.732	3.85	175	28	0	1	395.1	406	169	194	6	136	9	5		1,706	3	3.98	3.10	1.29	0.14	10.3	8.0	1.37	.290	4.42	9.24
24	Tommy Thomas T. Thomas	48	60	27	16	.628	3.07	143	29	1	0	398.2	370	136	162	19	102	7	8		1,646	6	3.23	2.30	1.40	0.43	8.7	6.2	1.18	.255	3.66	8.35
25	Jack Powell J. Powell	48	58	17	26	.395	1.40	172	39	4	3	410.1	372		174	10	87	9	9			4	3.77	1.91	1.98	0.22		5.8	1.12	.293	3.82	8.16