4 players were tied for the most strikeouts in a game in 2010, with 5 strikeouts. The first three are Ryan Howard on August 24, 2010, Justin Smoak on June 13, 2010 and Mark Teixeira on June 5, 2010.

Interpreted as:

MLB most k by a player in a regular-season game 2010

	NAME	SO	DATE	TM		OPP	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Ryan Howard R. Howard	5	8/24/2010	PHI	vs	HOU	7	0	0	0	0	0	0	0	0	0	0	7	0	0	0	0	0	0
2	Justin Smoak J. Smoak	5	6/13/2010	TEX	@	MIL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
3	Mark Teixeira M. Teixeira	5	6/5/2010	NYY	@	TOR	6	0	0	0	0	0	0	0	0	0	0	6	0	0	0	0	0	0
4	Jason Heyward J. Heyward	5	6/4/2010	ATL	@	LAD	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
5	Brent Lillibridge B. Lillibridge	4	10/3/2010	CWS	vs	CLE	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
6	Brian Bogusevic B. Bogusevic	4	10/3/2010	HOU	vs	CHC	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
7	Michael McKenry M. McKenry	4	10/3/2010	COL	@	STL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
8	Darnell McDonald D. McDonald	4	10/2/2010	BOS	vs	NYY	5	0	1	1	0	0	0	0	0	0	0	5	2	1	0	0	0	0
9	Corey Hart C. Hart	4	10/2/2010	MIL	@	CIN	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
10	Brent Lillibridge B. Lillibridge	4	10/1/2010	CWS	vs	CLE	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
11	Jay Bruce J. Bruce	4	10/1/2010	CIN	vs	MIL	4	0	0	0	0	0	0	1	0	0	0	5	0	0	0	0	1	0
12	Jonny Gomes J. Gomes	4	10/1/2010	CIN	vs	MIL	5	1	1	0	0	0	0	0	0	1	0	5	1	0	0	0	0	0
13	Shin-Soo Choo S. Choo	4	9/29/2010	CLE	vs	DET	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
14	Adam Dunn A. Dunn	4	9/29/2010	WSH	vs	PHI	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
15	Adam LaRoche A. LaRoche	4	9/24/2010	ARI	vs	LAD	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
16	Clayton Richard C. Richard	4	9/21/2010	SDP	@	LAD	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
17	Ryan Raburn R. Raburn	4	9/18/2010	DET	@	CWS	5	0	1	0	0	0	2	0	0	0	0	5	1	0	0	0	0	0
18	Miguel Cabrera M. Cabrera	4	9/17/2010	DET	@	CWS	5	1	1	0	0	0	0	0	0	0	0	5	1	0	0	0	0	0
19	Mark Teahen M. Teahen	4	9/17/2010	CWS	vs	DET	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
20	Austin Kearns A. Kearns	4	9/14/2010	NYY	@	TBR	5	0	1	0	0	0	0	0	0	0	0	5	1	0	0	0	0	0
21	Giancarlo Stanton G. Stanton	4	9/14/2010	FLA	vs	PHI	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
22	Ian Desmond I. Desmond	4	9/13/2010	WSH	@	ATL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
23	Micah Hoffpauir M. Hoffpauir	4	9/10/2010	CHC	@	MIL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
24	Austin Jackson A. Jackson	4	9/9/2010	DET	vs	CWS	4	1	0	0	0	0	0	1	0	0	0	5	0	0	0	0	0	0
25	Adam Lind A. Lind	4	9/8/2010	TOR	vs	TEX	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0