The Kansas City Royals scored the most runs by a team in their first game in 2021, with 14 runs versus the Rangers on April 1, 2021.

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Royals	14	4/1/2021	KCR	vs	TEX	W 14-10	38	15	0	0	3	13	8	2	8	0	0	50	24	3	0	2	0	0	.395	.500	.632	1.132
2	Cardinals	11	4/1/2021	STL	@	CIN	W 11-6	37	10	2	0	2	9	3	1	7	0	0	41	18	4	0	0	0	1	.270	.341	.486	.828
3	Rangers	10	4/1/2021	TEX	@	KCR	L 10-14	40	15	3	0	0	9	9	1	16	1	0	50	18	3	0	0	0	0	.375	.500	.450	.950
4	Padres	8	4/1/2021	SDP	vs	ARI	W 8-7	32	10	1	1	2	8	5	1	10	0	0	39	19	4	0	1	0	1	.313	.410	.594	1.004
5	Rockies	8	4/1/2021	COL	vs	LAD	W 8-5	35	11	1	1	0	5	3	0	4	2	1	39	14	2	1	0	0	0	.314	.368	.400	.768
6	Astros	8	4/1/2021	HOU	@	OAK	W 8-1	33	9	3	0	2	7	6	2	5	0	0	43	18	5	0	2	0	1	.273	.395	.545	.941
7	Mariners	8	4/1/2021	SEA	vs	SFG	W 8-7	32	5	3	0	0	7	9	1	9	0	0	43	8	3	0	1	0	0	.156	.349	.250	.599
8	Diamondbacks	7	4/1/2021	ARI	@	SDP	L 7-8	40	12	3	0	4	7	1	0	12	0	0	41	27	7	0	0	0	0	.300	.317	.675	.992
9	Giants	7	4/1/2021	SFG	@	SEA	L 7-8	39	10	3	0	4	6	4	0	7	0	0	43	25	7	0	0	1	1	.256	.326	.641	.967
10	Nationals	6	4/6/2021	WSH	vs	ATL	W 6-5	34	10	1	0	1	6	4	1	9	0	0	39	14	2	0	0	0	0	.294	.385	.412	.796
11	Brewers	6	4/1/2021	MIL	vs	MIN	W 6-5	40	11	1	0	0	6	2	2	9	0	0	44	12	1	0	0	0	0	.275	.341	.300	.641
12	Reds	6	4/1/2021	CIN	vs	STL	L 6-11	34	10	3	0	2	5	5	1	8	0	0	42	19	5	1	1	0	0	.294	.390	.559	.949
13	Pirates	5	4/1/2021	PIT	@	CHC	W 5-3	35	9	2	0	1	5	11	1	10	3	1	47	14	3	0	0	0	0	.257	.447	.400	.847
14	Twins	5	4/1/2021	MIN	@	MIL	L 5-6	39	10	2	1	1	4	7	0	17	1	0	47	17	4	1	0	0	0	.256	.370	.436	.805
15	Dodgers	5	4/1/2021	LAD	@	COL	L 5-8	36	15	3	1	0	5	8	1	6	0	0	46	20	4	0	1	0	3	.417	.522	.556	1.077
16	Angels	4	4/1/2021	LAA	vs	CWS	W 4-3	30	6	0	0	1	4	4	0	10	0	0	34	9	1	0	0	0	1	.200	.294	.300	.594
17	Mets	3	4/5/2021	NYM	@	PHI	L 3-5	36	10	0	0	0	3	4	0	11	0	0	40	10	0	0	0	0	2	.278	.350	.278	.628
18	Orioles	3	4/2/2021	BAL	@	BOS	W 3-0	34	9	2	0	0	3	2	0	7	0	0	36	11	2	0	0	0	2	.265	.306	.324	.629
19	Tigers	3	4/1/2021	DET	vs	CLE	W 3-2	30	5	1	0	1	3	5	0	14	1	0	35	9	2	0	0	0	0	.167	.286	.300	.586
20	Blue Jays	3	4/1/2021	TOR	@	NYY	W 3-2	36	8	1	0	1	3	2	0	13	0	1	38	12	2	0	0	0	1	.222	.263	.333	.596
21	Cubs	3	4/1/2021	CHC	vs	PIT	L 3-5	26	2	2	0	0	3	4	0	13	1	0	34	4	2	1	3	0	0	.077	.182	.154	.336
22	Phillies	3	4/1/2021	PHI	vs	ATL	W 3-2	36	9	2	0	0	3	4	1	13	1	0	43	11	2	1	1	1	0	.250	.333	.306	.639
23	White Sox	3	4/1/2021	CWS	@	LAA	L 3-4	33	7	2	0	1	2	2	0	10	1	1	35	12	3	0	0	0	0	.212	.257	.364	.621
24	Indians	2	4/1/2021	CLE	@	DET	L 2-3	32	6	1	0	1	2	6	0	5	0	0	38	10	2	0	0	0	1	.188	.316	.313	.628
25	Yankees	2	4/1/2021	NYY	vs	TOR	L 2-3	35	6	0	0	1	2	6	0	13	2	0	41	9	1	0	0	0	1	.171	.293	.257	.550