The San Francisco Giants put up the most runs by a team in a game in 1988, with 21 runs against the Cardinals on July 9, 1988.

Interpreted as:

MLB team most run in a regular-season game 1988

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Giants	21	7/9/1988	SFG	vs	STL	W 21-2	41	20	3	2	5	21	6	0	7	0	1	48	42	10	0	1	0	0	.488	.542	1.024	1.566
2	Tigers	18	8/14/1988	DET	@	BOS	W 18-6	42	19	4	0	2	18	8	0	2	0	0	52	29	6	0	2	0	2	.452	.519	.690	1.210
3	Yankees	18	4/18/1988	NYY	@	MIN	W 18-5	46	20	5	0	3	17	7	0	10	2	0	55	34	8	0	2	2	0	.435	.491	.739	1.230
4	Reds	17	9/4/1988	CIN	@	CHC	W 17-0	44	18	2	1	1	17	6	0	9	1	1	51	25	4	1	0	0	0	.409	.480	.568	1.048
5	Yankees	17	5/10/1988	NYY	vs	CWS	W 17-3	43	20	5	0	1	17	6	1	2	1	0	51	28	6	0	1	0	0	.465	.529	.651	1.181
6	Blue Jays	17	4/11/1988	TOR	vs	NYY	W 17-9	44	20	5	0	2	16	9	2	4	2	0	56	31	7	0	1	0	1	.455	.554	.705	1.258
7	Red Sox	16	8/13/1988	BOS	vs	DET	W 16-4	43	19	6	1	3	16	9	0	9	0	1	53	36	10	0	1	0	1	.442	.528	.837	1.366
8	Yankees	16	7/27/1988	NYY	vs	MIL	W 16-3	43	18	4	0	3	15	3	0	2	0	0	46	31	7	0	0	0	1	.419	.457	.721	1.177
9	Angels	16	6/27/1988	CAL	vs	MIN	W 16-7	39	17	3	0	2	16	7	0	5	0	0	49	26	5	1	2	0	0	.436	.500	.667	1.167
10	Brewers	16	6/12/1988	MIL	@	CWS	W 16-2	39	16	3	2	4	15	6	0	6	0	0	47	35	9	0	2	0	2	.410	.468	.897	1.366
11	Red Sox	16	5/5/1988	BOS	vs	CWS	W 16-3	40	18	6	0	1	15	6	0	2	0	0	47	27	7	1	0	0	1	.450	.522	.675	1.197
12	Blue Jays	15	9/27/1988	TOR	@	BOS	W 15-9	44	17	1	0	3	14	6	1	6	0	0	51	27	4	0	0	0	1	.386	.471	.614	1.084
13	Angels	15	8/16/1988	CAL	@	NYY	W 15-6	46	19	6	0	2	15	1	1	6	0	0	48	31	8	0	0	0	0	.413	.438	.674	1.111
14	Giants	15	8/14/1988	SFG	@	LAD	W 15-4	46	20	3	1	2	12	3	0	7	1	0	51	31	6	1	1	1	1	.435	.460	.674	1.134
15	Angels	15	7/30/1988	CAL	@	CWS	W 15-14	39	16	2	0	5	14	7	0	8	0	1	47	33	7	0	1	1	1	.410	.489	.846	1.336
16	Red Sox	15	6/19/1988	BOS	@	BAL	W 15-7	49	23	4	0	3	15	2	0	2	0	0	51	36	7	0	0	0	1	.469	.490	.735	1.225
17	Blue Jays	15	6/15/1988	TOR	vs	CLE	W 15-3	38	17	3	2	4	13	5	2	4	0	0	46	36	9	1	0	0	1	.447	.533	.947	1.481
18	Twins	15	5/22/1988	MIN	@	TEX	W 15-5	44	16	5	0	1	13	4	0	2	1	0	49	24	6	0	1	0	0	.364	.408	.545	.954
19	Yankees	15	4/30/1988	NYY	vs	TEX	W 15-3	36	11	0	0	3	14	10	0	7	4	0	46	20	3	0	0	1	1	.306	.457	.556	1.012
20	Red Sox	15	4/17/1988	BOS	vs	TEX	W 15-2	39	20	4	1	2	15	6	0	3	0	0	46	32	7	1	0	1	3	.513	.578	.821	1.398
21	Angels	15	4/12/1988	CAL	vs	CWS	W 15-6	39	14	1	0	3	14	6	0	5	0	0	45	24	4	0	0	0	0	.359	.444	.615	1.060
22	Mets	14	9/24/1988	NYM	@	STL	W 14-1	42	14	5	0	3	13	6	0	6	0	0	48	28	8	0	0	0	0	.333	.417	.667	1.083
23	Expos	14	9/12/1988	MON	vs	STL	W 14-2	37	13	3	0	0	14	9	0	6	6	1	46	16	3	0	0	3	0	.351	.478	.432	.911
24	Athletics	14	9/9/1988	OAK	@	KCR	W 14-6	42	15	1	2	0	12	6	0	3	4	0	48	20	3	0	0	0	1	.357	.438	.476	.914
25	Cubs	14	9/5/1988	CHC	vs	PHI	W 14-3	35	13	2	0	0	12	12	1	4	1	0	50	15	2	0	2	0	0	.371	.520	.429	.949