The Los Angeles Dodgers scored the most runs by a team in a game in 2001, with 22 runs against the Rockies on July 21, 2001.

Interpreted as:

MLB team most run in a regular-season game 2001

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	22	7/21/2001	LAD	@	COL	W 22-7	48	23	3	1	4	20	2	3	4	0	0	54	40	8	1	0	1	1	.479	.528	.833	1.362
2	Braves	20	10/5/2001	ATL	vs	FLA	W 20-3	34	14	2	1	2	20	12	0	7	0	0	48	24	5	0	2	0	2	.412	.542	.706	1.248
3	Padres	20	5/19/2001	SDP	@	MON	W 20-7	46	20	3	0	4	19	7	2	4	1	0	57	35	7	1	1	0	0	.435	.518	.761	1.279
4	Cubs	20	5/5/2001	CHC	vs	LAD	W 20-1	39	18	2	0	3	17	9	0	13	0	1	50	29	5	2	0	0	2	.462	.563	.744	1.306
5	White Sox	19	9/2/2001	CWS	vs	CLE	W 19-10	40	17	3	0	3	18	9	1	6	0	0	50	29	6	0	0	0	1	.425	.540	.725	1.265
6	Tigers	19	8/8/2001	DET	@	TEX	W 19-6	47	21	4	1	5	19	5	1	5	1	0	54	42	10	0	1	1	0	.447	.500	.894	1.394
7	Tigers	18	5/18/2001	DET	@	TBD	W 18-2	46	19	3	2	1	18	4	1	10	2	0	52	29	6	0	1	0	1	.413	.462	.630	1.092
8	Reds	17	8/26/2001	CIN	@	MON	W 17-4	48	20	8	1	4	17	2	0	12	0	0	50	42	13	0	0	0	0	.417	.440	.875	1.315
9	Athletics	17	8/2/2001	OAK	@	CLE	W 17-4	47	20	2	0	3	16	5	0	5	3	1	52	31	5	0	0	0	0	.426	.481	.660	1.140
10	Astros	17	7/18/2001	HOU	vs	STL	W 17-11	37	16	5	2	4	16	7	2	8	1	0	49	37	11	2	1	0	0	.432	.532	1.000	1.532
11	Diamondbacks	17	4/17/2001	ARI	@	STL	W 17-4	43	18	5	1	5	15	6	0	2	0	1	50	40	11	1	0	0	1	.419	.490	.930	1.420
12	Mariners	16	10/4/2001	SEA	vs	TEX	W 16-1	43	19	6	0	1	16	6	1	8	2	0	50	28	7	0	0	0	0	.442	.520	.651	1.171
13	Cardinals	16	8/29/2001	STL	vs	SDP	W 16-14	40	15	4	0	3	13	1	0	6	3	0	41	28	7	0	0	0	0	.375	.390	.700	1.090
14	Mariners	16	8/22/2001	SEA	vs	DET	W 16-1	42	20	5	1	4	15	4	1	5	0	0	47	39	10	0	0	0	2	.476	.532	.929	1.460
15	Cubs	16	8/22/2001	CHC	vs	MIL	W 16-3	41	17	3	1	3	15	8	1	9	0	0	50	31	7	0	0	1	0	.415	.520	.756	1.276
16	Rockies	16	8/10/2001	COL	@	CIN	W 16-7	44	15	4	0	2	13	4	0	5	1	0	48	25	6	0	0	0	0	.341	.396	.568	.964
17	Yankees	16	8/8/2001	NYY	@	TBD	W 16-1	42	17	1	0	3	16	8	1	10	0	0	52	27	4	0	1	0	0	.405	.500	.643	1.143
18	Red Sox	16	7/2/2001	BOS	@	TOR	W 16-4	42	17	5	0	2	16	8	0	4	0	1	50	28	7	0	0	0	0	.405	.500	.667	1.167
19	Rangers	16	6/9/2001	TEX	vs	HOU	W 16-4	39	17	3	1	5	16	5	0	1	0	0	45	37	9	0	1	0	1	.436	.489	.949	1.438
20	Rangers	16	5/12/2001	TEX	@	CWS	W 16-6	42	14	2	0	4	16	8	0	6	0	0	50	28	6	0	0	0	1	.333	.440	.667	1.107
21	Athletics	16	4/26/2001	OAK	@	CWS	W 16-6	43	17	7	0	4	16	5	1	5	0	0	49	36	11	0	0	0	0	.395	.469	.837	1.307
22	Yankees	16	4/8/2001	NYY	vs	TOR	W 16-5	42	20	5	0	1	15	6	0	5	0	0	49	28	6	0	1	0	1	.476	.531	.667	1.197
23	Brewers	15	10/7/2001	MIL	vs	ARI	W 15-5	41	16	5	0	1	14	3	2	8	0	0	46	24	6	0	0	0	1	.390	.457	.585	1.042
24	Diamondbacks	15	9/26/2001	ARI	vs	MIL	W 15-9	41	18	3	0	1	14	10	0	3	0	0	52	24	4	1	0	1	0	.439	.549	.585	1.134
25	Rockies	15	9/24/2001	COL	vs	SDP	W 15-11	41	20	4	2	3	14	5	3	4	2	0	50	37	9	0	1	0	1	.488	.560	.902	1.462