The Cleveland Indians had the most runs by a team in a game in 1917, with 20 runs versus the Philadelphia Athletics on July 22, 1917.

Interpreted as:

MLB team most runs in a regular-season game 1917

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	PA	TB	XBH	SH	AVG	OBP	SLG	OPS
1	Indians	20	7/22/1917	CLE	vs	PHA	W 20-6	38	17	2	0	1	20	5	0	1	3	48	22	3	5	.447	.512	.579	1.091
2	Tigers	19	6/29/1917	DET	@	SLA	W 19-1	41	19	2	2	2		9	0	4	4	54	31	6	4	.463	.560	.756	1.316
3	Reds	19	5/24/1917	CIN	@	PHN	W 19-9	46	19	5	1	2		6	1	2	4	54	32	8	1	.413	.491	.696	1.186
4	Indians	16	8/21/1917	CLE	vs	PHA	W 16-3	44	21	5	0	0	14	4	0	1	2	48	26	5	0	.477	.521	.591	1.112
5	Tigers	16	7/30/1917	DET	@	WSH	W 16-4	45	21	0	2	0		5	1	5	2	52	25	2	1	.467	.529	.556	1.085
6	Athletics	16	4/14/1917	PHA	vs	WSH	W 16-4	42	20	2	2	1	15	4	0	4	1	49	29	5	3	.476	.522	.690	1.212
7	Tigers	15	8/29/1917	DET	@	CLE	W 15-1	40	18	5	0	0	13	6	0	8	0	47	23	5	1	.450	.522	.575	1.097
8	Browns	15	7/1/1917	SLA	vs	DET	W 15-9	39	16	4	0	0	11	2	1	2	3	45	20	4	3	.410	.452	.513	.965
9	Reds	15	6/24/1917	CIN	@	SLN	W 15-4	46	25	4	1	1		1	0	0	6	49	34	6	2	.543	.553	.739	1.292
10	White Sox	14	9/3/1917	CWS	vs	DET	W 14-8	40	17	2	0	1		4	1	2	5	46	22	3	1	.425	.489	.550	1.039
11	White Sox	14	8/19/1917	CWS	vs	PHA	W 14-6	35	14	4	3	0	11	8	0	1	5	45	24	7	2	.400	.512	.686	1.197
12	Athletics	14	6/30/1917	PHA	vs	WSH	W 14-6	41	19	4	0	2	13	5	1	6	2	48	29	6	1	.463	.532	.707	1.239
13	Red Sox	13	9/29/1917	BSA	vs	SLA	W 13-5	32	16	2	4	0		7	0	1	1	46	26	6	7	.500	.590	.813	1.402
14	Braves	13	9/25/1917	BSN	@	CIN	W 13-0	37	17	4	2	0		5	1	5	4	46	25	6	3	.459	.535	.676	1.211
15	Yankees	13	9/13/1917	NYY	vs	BSA	W 13-7	41	17	3	1	2		2	0	1	1	43	28	6	0	.415	.442	.683	1.125
16	Robins	13	9/10/1917	BKN	@	NYG	W 13-6	42	13	4	1	0	12	4	1	3	4	47	19	5	0	.310	.383	.452	.835
17	White Sox	13	9/4/1917	CWS	@	SLA	W 13-6	38	16	3	0	0	10	6	1	2	6	48	19	3	3	.421	.511	.500	1.011
18	Athletics	13	7/11/1917	PHA	@	SLA	W 13-5	36	15	4	0	0	13	6	0	3	0	46	19	4	4	.417	.500	.528	1.028
19	Reds	13	7/4/1917	CIN	@	CHC	W 13-10	40	16	2	0	1		2	1	7	1	45	21	3	2	.400	.442	.525	.967
20	Braves	13	6/29/1917	BSN	@	NYG	W 13-0	45	18	2	1	1	9	4	1	3	4	50	25	4	0	.400	.460	.556	1.016
21	Robins	13	5/17/1917	BKN	vs	CIN	W 13-10	36	14	1	1	0		6	0	2	3	44	17	2	2	.389	.476	.472	.948
22	Yankees	12	9/29/1917	NYY	vs	CWS	W 12-8	37	15	3	0	1	11	4	0	2	2	42	21	4	1	.405	.463	.568	1.031
23	Athletics	12	9/29/1917	PHA	vs	DET	W 12-11	40	12	0	1	0	8	7	0	4	1	48	14	1	1	.300	.404	.350	.754
24	Cardinals	12	9/18/1917	SLN	vs	BKN	W 12-4	32	13	1	1	0		5	0	2	2	39	16	2	2	.406	.486	.500	.986
25	Braves	12	9/10/1917	BSN	vs	PHN	W 12-2	34	14	3	4	1	10	4	0	2	3	40	28	8	2	.412	.474	.824	1.297