The New York Yankees had the most runs by an AL team in a game with >0 games played in 2011, with 22 runs against the Oakland Athletics on August 25, 2011.

Interpreted as:

MLB team most runs in a regular-season game 2011 al

	TEAM	R	G	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	22	1	8/25/2011	NYY	vs	OAK	W 22-9	43	21	2	1	5	22	13	1	9	0	0	58	40	8	0	1	1	0	.488	.603	.930	1.534
2	Rangers	20	1	7/25/2011	TEX	vs	MIN	W 20-6	52	27	8	1	2	19	4	0	4	0	0	57	43	11	0	1	1	0	.519	.544	.827	1.371
3	Indians	19	1	5/16/2011	CLE	@	KCR	W 19-1	44	20	7	0	1	19	8	0	5	3	0	53	30	8	1	0	0	1	.455	.538	.682	1.220
4	Red Sox	18	1	9/19/2011	BOS	vs	BAL	W 18-9	43	20	3	0	3	17	8	0	6	1	0	51	32	6	0	0	1	0	.465	.549	.744	1.293
5	Red Sox	18	1	9/13/2011	BOS	vs	TOR	W 18-6	39	18	6	0	3	16	4	1	3	0	0	47	33	9	1	2	0	1	.462	.500	.846	1.346
6	Tigers	18	1	9/4/2011	DET	vs	CWS	W 18-2	48	24	5	0	2	17	3	1	12	0	0	52	35	7	0	0	0	0	.500	.538	.729	1.268
7	Yankees	18	1	8/3/2011	NYY	@	CWS	W 18-7	48	23	4	2	2	18	2	1	9	1	0	52	37	8	0	1	0	1	.479	.500	.771	1.271
8	Yankees	17	1	7/30/2011	NYY	vs	BAL	W 17-3	48	24	6	1	2	17	4	0	7	0	0	52	38	9	0	0	0	1	.500	.538	.792	1.330
9	Yankees	17	1	7/22/2011	NYY	vs	OAK	W 17-7	38	17	1	0	2	17	9	1	10	2	0	49	24	3	0	1	0	1	.447	.551	.632	1.183
10	Blue Jays	16	1	7/14/2011	TOR	vs	NYY	W 16-7	43	20	5	0	0	14	3	0	5	1	0	46	25	5	0	0	0	2	.465	.500	.581	1.081
11	Royals	16	1	7/3/2011	KCR	@	COL	W 16-8	48	21	9	0	3	16	2	3	6	1	1	53	39	12	0	0	0	0	.438	.491	.813	1.303
12	Red Sox	16	1	6/11/2011	BOS	@	TOR	W 16-4	44	18	3	0	2	16	6	2	7	0	0	53	27	5	0	1	1	0	.409	.491	.614	1.104
13	Rays	16	1	4/11/2011	TBR	@	BOS	W 16-5	45	19	6	1	2	15	3	0	4	0	0	48	33	9	0	0	0	1	.422	.458	.733	1.192
14	Rays	15	1	9/22/2011	TBR	@	NYY	W 15-8	43	17	1	1	3	14	8	2	3	0	0	56	29	5	0	3	0	1	.395	.482	.674	1.157
15	Athletics	15	1	8/26/2011	OAK	@	BOS	W 15-5	45	16	8	0	2	15	5	0	4	0	0	50	30	10	0	0	0	0	.356	.420	.667	1.087
16	Red Sox	15	1	7/18/2011	BOS	@	BAL	W 15-10	43	16	2	0	2	14	5	0	6	0	0	49	24	4	0	1	1	0	.372	.429	.558	.987
17	Rangers	15	1	7/1/2011	TEX	vs	FLA	W 15-5	39	15	5	1	2	15	6	1	6	1	0	46	28	8	0	0	1	0	.385	.478	.718	1.196
18	Red Sox	15	1	5/20/2011	BOS	vs	CHC	W 15-5	42	19	6	0	2	13	6	0	5	2	0	49	31	8	0	1	0	1	.452	.510	.738	1.248
19	Rays	15	1	4/28/2011	TBR	@	MIN	W 15-3	45	19	3	1	2	14	6	0	6	3	0	52	30	6	0	1	0	1	.422	.481	.667	1.147
20	Yankees	15	1	4/23/2011	NYY	@	BAL	W 15-3	40	14	3	0	5	15	5	1	6	0	0	46	32	8	0	0	0	1	.350	.435	.800	1.235
21	Angels	15	1	4/19/2011	LAA	@	TEX	W 15-4	41	15	3	0	3	12	6	0	6	0	1	47	27	6	0	0	0	1	.366	.447	.659	1.105
22	White Sox	15	1	4/1/2011	CWS	@	CLE	W 15-10	45	18	6	0	2	15	2	1	14	0	0	48	30	8	0	0	0	0	.400	.438	.667	1.104
23	Tigers	14	1	9/26/2011	DET	vs	CLE	W 14-0	41	18	5	1	1	14	3	2	7	0	0	46	28	7	0	0	0	1	.439	.500	.683	1.183
24	Tigers	14	1	9/12/2011	DET	@	CWS	W 14-4	46	21	5	0	2	13	5	1	6	0	0	52	32	7	0	0	0	2	.457	.519	.696	1.215
25	Red Sox	14	1	9/6/2011	BOS	@	TOR	W 14-0	47	20	9	0	2	14	5	0	11	0	0	52	35	11	0	0	0	0	.426	.481	.745	1.225