Since 2000, the Kansas City Royals have the fewest wins by a team, with 1,773 wins.

Interpreted as:

MLB team with least regular-season wins since 2000

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Royals	1,773	2,249	.441	4,022	137,618	17,487	35,887	6,958	877	3,506	16,577	10,777	1,375	27,047	2,799	991	151,821	55,117	11,341	894	1,157	606	3,121	.261	.318	.401	.719
2	Pirates	1,796	2,221	.447	4,018	136,072	16,709	34,061	6,800	767	3,676	15,935	12,160	1,649	30,678	2,101	950	152,163	53,423	11,243	1,288	994	871	2,906	.250	.317	.393	.710
3	Rockies	1,826	2,197	.454	4,023	137,875	19,437	36,720	7,381	1,027	4,426	18,511	12,735	1,244	31,343	2,231	951	154,421	59,433	12,834	1,498	1,069	954	3,017	.266	.332	.431	.763
4	Orioles	1,836	2,183	.457	4,021	137,929	18,036	35,488	6,961	516	4,644	17,236	11,584	1,398	29,001	2,095	800	152,629	57,413	12,121	667	1,051	598	3,097	.257	.319	.416	.735
5	Marlins	1,860	2,156	.463	4,016	136,460	16,878	34,686	6,727	764	3,768	16,021	12,016	1,479	31,297	2,534	960	152,274	54,245	11,259	1,327	992	937	3,000	.254	.319	.398	.717
6	Tigers	1,888	2,129	.470	4,017	137,707	17,943	35,855	6,877	952	4,140	17,169	11,812	1,236	30,143	1,822	824	152,582	57,056	11,969	738	1,089	676	3,105	.260	.322	.414	.736
7	Reds	1,900	2,122	.472	4,024	136,363	17,939	34,303	6,801	603	4,610	17,130	13,242	1,703	31,780	2,547	965	153,681	56,140	12,014	1,394	979	934	2,850	.252	.323	.412	.735
8	Nationals	1,908	2,112	.475	4,020	135,819	17,465	34,612	7,043	663	4,010	16,608	12,868	1,454	29,594	2,485	968	152,631	55,011	11,716	1,465	1,025	1,031	3,072	.255	.324	.405	.729
9	Padres	1,927	2,095	.479	4,022	135,722	16,959	33,575	6,509	727	3,857	16,120	13,310	1,246	31,059	2,499	886	152,520	53,109	11,093	1,192	1,050	859	2,906	.247	.318	.391	.709
10	White Sox	1,934	2,087	.481	4,021	136,817	18,101	35,134	6,651	562	4,647	17,346	11,681	1,521	29,529	2,239	989	151,918	56,850	11,860	877	1,022	549	3,113	.257	.320	.416	.736
11	Diamondbacks	1,958	2,063	.487	4,021	137,090	18,298	34,846	7,223	981	4,272	17,452	13,368	1,323	30,542	2,308	830	154,128	56,847	12,476	1,223	1,124	1,009	2,879	.254	.324	.415	.739
12	Rangers	1,973	2,050	.490	4,023	138,113	19,536	36,019	7,129	662	4,967	18,610	12,502	1,466	30,011	2,450	879	153,927	59,373	12,758	728	1,118	685	2,887	.261	.326	.430	.756
13	Brewers	1,999	2,023	.497	4,023	135,895	17,899	34,074	6,865	675	4,625	17,099	13,259	1,668	32,616	2,715	913	153,020	56,164	12,165	1,235	963	924	3,022	.251	.323	.413	.736
14	Rays	2,000	2,020	.498	4,020	136,547	17,939	34,509	6,932	781	4,274	17,082	13,032	1,586	31,486	3,056	1,114	152,900	55,825	11,987	660	1,075	640	2,756	.253	.323	.409	.732
15	Mariners	2,012	2,009	.500	4,021	137,072	17,648	34,651	6,544	579	4,194	16,799	12,689	1,494	30,228	2,573	930	153,074	54,935	11,317	775	1,044	767	2,887	.253	.321	.401	.721
16	Cubs	2,014	2,005	.501	4,020	136,689	18,127	34,676	7,002	720	4,527	17,265	13,160	1,573	31,407	2,051	840	153,728	56,699	12,249	1,325	981	953	2,962	.254	.324	.415	.739
17	Blue Jays	2,017	2,003	.502	4,020	137,597	18,985	35,514	7,453	576	4,906	18,135	12,908	1,443	28,914	1,943	722	153,593	58,837	12,935	563	1,082	594	3,215	.258	.326	.428	.753
18	Twins	2,020	2,002	.502	4,022	137,886	18,577	35,852	7,256	769	4,151	17,626	12,841	1,402	29,280	2,097	867	153,932	57,099	12,176	691	1,112	753	3,135	.260	.327	.414	.741
19	Mets	2,021	1,999	.503	4,020	136,240	17,634	34,378	6,799	658	4,242	16,830	13,166	1,624	29,557	2,406	814	153,326	55,219	11,699	1,286	1,010	1,053	2,994	.252	.323	.405	.729
20	Athletics	2,060	1,962	.512	4,022	136,809	18,277	34,139	7,043	581	4,419	17,419	13,924	1,438	29,512	1,915	621	153,786	55,601	12,043	530	1,085	611	3,176	.250	.323	.406	.729
21	Phillies	2,063	1,958	.513	4,021	137,384	18,466	34,967	7,023	798	4,478	17,612	13,627	1,508	30,795	2,594	694	154,712	57,020	12,299	1,201	992	1,133	2,781	.255	.326	.415	.741
22	Angels	2,070	1,951	.515	4,021	137,177	18,488	35,607	6,797	657	4,350	17,601	12,196	1,445	28,039	2,691	1,062	152,758	56,768	11,804	820	1,120	878	3,089	.260	.324	.414	.738
23	Astros	2,072	1,948	.515	4,021	136,738	18,525	35,297	7,059	627	4,626	17,676	12,959	1,531	29,233	2,305	918	153,453	57,488	12,312	1,145	1,080	819	3,205	.258	.327	.420	.747
24	Guardians	2,083	1,934	.519	4,017	136,927	18,784	35,367	7,348	634	4,360	17,896	13,416	1,575	29,166	2,440	876	153,911	57,063	12,342	825	1,168	770	3,043	.258	.329	.417	.746
25	Giants	2,093	1,926	.521	4,020	136,727	17,596	34,889	7,020	853	3,906	16,750	12,951	1,302	28,843	1,809	763	153,434	55,333	11,779	1,317	1,137	1,240	3,136	.255	.323	.405	.728