Since 2019, the Colorado Rockies have the fewest wins by a team, with 378 wins.

Interpreted as:

MLB team with least regular-season wins since 2019

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rockies	378	575	.397	953	32,393	4,245	8,101	1,679	206	1,039	4,074	2,719	311	8,724	440	160	35,818	13,309	2,924	154	241	104	701	.250	.312	.411	.723
2	Pirates	398	557	.417	955	31,958	3,831	7,604	1,487	170	883	3,649	2,915	325	8,273	526	184	35,579	12,080	2,540	153	228	119	617	.238	.306	.378	.684
3	Royals	405	549	.425	954	32,009	3,953	7,873	1,539	207	922	3,787	2,550	330	7,609	755	233	35,310	12,592	2,668	138	283	82	577	.246	.306	.393	.699
4	Marlins	407	545	.428	952	32,030	3,743	7,770	1,464	125	896	3,572	2,558	357	8,356	612	192	35,287	12,172	2,485	133	209	98	716	.243	.304	.380	.684
5	White Sox	411	542	.431	953	32,170	3,931	7,888	1,517	86	986	3,755	2,577	354	8,329	431	138	35,421	12,535	2,589	123	197	64	712	.245	.307	.390	.696
6	Nationals	416	538	.436	954	32,013	4,219	8,115	1,622	134	986	4,005	2,913	446	7,286	704	230	35,774	12,963	2,742	173	229	131	736	.253	.322	.405	.727
7	Angels	425	528	.446	953	32,038	4,142	7,672	1,436	133	1,205	3,959	2,965	414	8,447	484	180	35,718	12,989	2,774	92	209	142	677	.239	.310	.405	.716
8	Tigers	430	522	.452	952	31,990	3,852	7,635	1,468	212	933	3,702	2,662	308	8,759	402	129	35,270	12,326	2,613	59	251	60	615	.239	.301	.385	.686
9	Athletics	432	524	.452	956	31,846	4,012	7,424	1,501	117	1,135	3,823	3,064	441	8,306	534	135	35,672	12,564	2,753	100	221	74	701	.233	.307	.395	.702
10	Rangers	437	517	.458	954	32,202	4,238	7,757	1,486	118	1,142	4,030	2,919	337	8,337	662	185	35,757	12,905	2,746	66	233	90	569	.241	.309	.401	.709
11	Orioles	442	511	.464	953	32,300	4,274	7,934	1,591	143	1,172	4,096	2,790	394	8,250	522	164	35,814	13,327	2,906	93	237	71	589	.246	.311	.413	.724
12	Diamondbacks	450	503	.472	953	32,254	4,527	7,960	1,652	206	1,092	4,309	3,192	401	7,783	604	141	36,317	13,300	2,950	178	292	116	641	.247	.320	.412	.732
13	Reds	454	500	.476	954	31,735	4,247	7,632	1,504	137	1,158	4,069	3,071	524	8,517	665	220	35,662	12,884	2,799	120	212	79	651	.240	.316	.406	.722
14	Cubs	478	476	.501	954	31,969	4,449	7,810	1,512	167	1,189	4,249	3,223	480	8,484	649	189	36,037	13,223	2,868	129	236	114	652	.244	.321	.414	.734
15	Red Sox	478	477	.501	955	32,954	4,679	8,535	1,954	131	1,178	4,460	3,030	378	8,418	517	167	36,672	14,285	3,263	71	239	150	684	.259	.326	.433	.760
16	Blue Jays	490	463	.514	953	32,328	4,431	8,182	1,677	99	1,224	4,251	3,042	343	7,577	447	145	36,001	13,729	3,000	75	213	88	711	.253	.322	.425	.747
17	Mariners	491	462	.515	953	31,855	4,213	7,421	1,428	92	1,197	4,047	3,335	523	8,979	649	194	36,001	12,624	2,717	67	221	78	585	.233	.314	.396	.710
18	Padres	495	458	.519	953	31,904	4,298	7,864	1,532	118	1,115	4,107	3,244	344	7,678	598	187	35,900	12,977	2,765	171	237	134	694	.246	.321	.407	.727
19	Twins	497	457	.521	954	32,373	4,509	8,048	1,644	116	1,316	4,312	3,069	486	8,274	325	115	36,220	13,872	3,076	53	239	91	682	.249	.321	.429	.749
20	Giants	498	456	.522	954	32,068	4,213	7,691	1,576	140	1,102	4,038	3,184	403	8,504	365	121	36,018	12,853	2,818	115	248	133	677	.240	.314	.401	.715
21	Mets	502	453	.526	955	32,059	4,338	7,989	1,521	118	1,206	4,170	3,051	595	7,873	480	132	36,029	13,364	2,845	115	209	128	707	.249	.324	.417	.741
22	Cardinals	505	448	.530	953	31,956	4,276	7,911	1,536	111	1,117	4,081	3,097	445	7,766	558	159	35,879	13,020	2,764	128	253	100	631	.248	.320	.407	.728
23	Guardians	508	443	.534	951	31,764	4,105	7,724	1,556	131	1,002	3,893	2,899	389	7,375	720	190	35,445	12,548	2,689	130	263	170	640	.243	.312	.395	.707
24	Phillies	512	442	.537	954	32,310	4,527	8,117	1,628	153	1,206	4,339	3,177	367	8,215	655	144	36,215	13,669	2,987	129	232	167	625	.251	.323	.423	.746
25	Brewers	531	423	.557	954	31,910	4,381	7,661	1,495	114	1,159	4,190	3,492	412	8,619	739	186	36,129	12,861	2,768	96	219	145	676	.240	.321	.403	.724