Since 2020, the Colorado Rockies have the fewest wins by a team, with 300 wins.

Interpreted as:

MLB team with least regular-season wins since 2020

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rockies	300	469	.390	769	25,968	3,311	6,404	1,315	156	789	3,176	2,168	259	6,988	354	122	28,691	10,398	2,260	102	194	79	568	.247	.309	.400	.709
2	Pirates	317	453	.412	770	25,537	2,973	5,914	1,137	128	703	2,830	2,424	256	6,856	449	148	28,504	9,416	1,968	103	184	77	481	.232	.303	.369	.671
3	Nationals	317	452	.412	769	25,711	3,250	6,458	1,286	106	731	3,088	2,262	358	5,817	571	192	28,631	10,149	2,123	119	181	90	604	.251	.318	.395	.713
4	Athletics	324	447	.420	771	25,515	3,074	5,861	1,181	93	849	2,933	2,411	348	6,775	473	111	28,548	9,775	2,123	92	182	57	543	.230	.303	.383	.686
5	White Sox	330	440	.429	770	25,918	3,150	6,284	1,224	62	787	3,014	2,125	283	6,576	358	105	28,567	9,993	2,073	82	159	48	583	.242	.305	.386	.691
6	Marlins	336	432	.438	768	25,736	3,015	6,230	1,157	102	729	2,869	2,096	281	6,708	538	155	28,380	9,778	1,988	99	168	81	567	.242	.304	.380	.684
7	Royals	339	430	.441	769	25,743	3,189	6,336	1,218	164	738	3,060	2,037	265	6,053	622	187	28,394	10,096	2,120	110	239	61	447	.246	.305	.392	.698
8	Angels	340	429	.442	769	25,756	3,269	6,130	1,142	110	949	3,126	2,309	328	6,954	407	152	28,644	10,339	2,201	87	164	108	521	.238	.307	.401	.708
9	Rangers	347	423	.451	770	25,886	3,329	6,197	1,148	92	897	3,173	2,303	257	6,582	514	142	28,673	10,220	2,137	47	180	65	457	.239	.306	.395	.701
10	Diamondbacks	354	415	.460	769	25,864	3,588	6,347	1,334	160	836	3,407	2,581	322	6,237	505	121	29,149	10,509	2,330	142	240	78	507	.245	.319	.406	.725
11	Reds	365	406	.473	771	25,579	3,439	6,120	1,238	107	904	3,289	2,514	429	6,908	577	179	28,780	10,284	2,249	87	171	53	524	.239	.316	.402	.718
12	Tigers	371	398	.482	769	25,702	3,161	6,103	1,138	162	751	3,039	2,210	249	6,992	336	108	28,406	9,818	2,051	49	196	44	497	.237	.302	.382	.684
13	Orioles	376	392	.490	768	25,933	3,430	6,364	1,300	117	925	3,290	2,261	310	6,613	423	130	28,768	10,673	2,342	70	194	59	465	.245	.311	.412	.723
14	Cubs	383	386	.498	769	25,710	3,531	6,237	1,209	139	890	3,363	2,583	392	6,846	584	162	28,977	10,394	2,238	98	194	80	518	.243	.319	.404	.723
15	Red Sox	383	389	.496	772	26,484	3,682	6,819	1,570	99	906	3,514	2,373	315	6,834	435	133	29,410	11,305	2,575	49	189	111	542	.257	.324	.427	.751
16	Twins	390	379	.507	769	25,877	3,473	6,320	1,291	92	974	3,310	2,470	395	6,750	290	92	28,979	10,717	2,357	42	195	69	564	.244	.317	.414	.732
17	Cardinals	400	366	.522	766	25,654	3,389	6,365	1,257	87	874	3,249	2,465	352	6,153	430	127	28,763	10,418	2,218	85	207	82	507	.248	.320	.406	.726
18	Mets	407	363	.529	770	25,649	3,454	6,349	1,210	101	926	3,310	2,464	490	6,296	407	103	28,866	10,539	2,237	87	176	93	563	.248	.323	.411	.734
19	Guardians	408	359	.532	767	25,633	3,274	6,229	1,241	111	761	3,102	2,270	334	5,846	597	150	28,538	9,975	2,113	87	214	137	514	.243	.310	.389	.700
20	Giants	410	360	.532	770	25,790	3,442	6,200	1,247	109	915	3,298	2,619	339	6,887	311	89	29,027	10,410	2,271	84	195	106	550	.240	.316	.404	.720
21	Blue Jays	410	359	.533	769	26,071	3,593	6,678	1,370	77	954	3,448	2,470	286	5,928	388	120	29,062	11,064	2,401	57	178	74	587	.256	.325	.424	.750
22	Mariners	412	356	.536	768	25,523	3,341	5,887	1,132	63	931	3,207	2,679	450	7,201	510	143	28,876	9,938	2,126	48	176	61	484	.231	.313	.389	.702
23	Padres	415	353	.540	768	25,748	3,522	6,399	1,271	91	876	3,365	2,661	282	5,933	517	147	29,020	10,480	2,238	130	199	112	558	.249	.323	.407	.730
24	Phillies	419	350	.545	769	25,970	3,657	6,554	1,275	125	970	3,504	2,548	300	6,577	562	122	29,104	10,989	2,370	92	194	117	513	.252	.324	.423	.747
25	Brewers	429	342	.556	771	25,671	3,503	6,105	1,184	94	888	3,343	2,788	332	6,894	621	151	29,033	10,141	2,166	73	169	101	541	.238	.319	.395	.714