Between the 1900 and 1946 seasons, the New York Giants had the most wins by a team, with 3,962 wins.

Interpreted as:

MLB team with most regular-season wins 1900 to 1946

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	PA	TB	XBH	SH	GIDP	AVG	OBP	SLG	OPS
1	Giants	3,962	3,116	.560	7,160	243,757	32,995	66,584	9,890	2,762	3,334	29,355	20,608	2,000	22,145	6,232	272,332	92,000	15,986	5,967	1,039	.273	.335	.377	.712
2	Cubs	3,943	3,168	.554	7,188	243,285	32,172	65,170	10,694	2,851	2,696	28,328	21,805	1,629	24,537	5,929	274,180	89,654	16,241	7,461	887	.268	.332	.369	.701
3	Pirates	3,903	3,193	.550	7,170	245,234	32,643	67,005	10,212	4,112	1,967	28,853	20,833	1,492	21,437	5,853	274,193	91,342	16,291	6,634	950	.273	.334	.372	.706
4	Yankees	3,765	2,889	.566	6,723	228,297	33,158	61,651	9,703	3,050	3,966	29,761	23,933	1,644	24,829	5,248	259,832	89,352	16,719	5,958	898	.270	.344	.391	.735
5	Tigers	3,635	3,323	.522	7,029	239,560	33,517	65,669	10,881	3,376	2,460	29,503	23,544	1,444	23,057	5,868	271,637	90,682	16,717	7,089	1,026	.274	.343	.379	.721
6	Cardinals	3,613	3,483	.509	7,178	245,628	32,041	66,545	10,811	3,326	2,698	28,415	20,269	1,636	24,839	5,416	273,920	92,102	16,835	6,387	764	.271	.331	.375	.706
7	Indians	3,583	3,370	.515	7,028	239,257	31,774	65,282	11,932	3,210	2,142	28,279	21,139	1,542	23,825	5,016	269,118	90,060	17,284	7,180	899	.273	.336	.376	.712
8	White Sox	3,474	3,456	.501	7,006	235,864	29,998	61,810	9,810	2,897	1,483	26,291	22,120	1,626	22,387	6,359	267,347	81,863	14,190	7,737	937	.262	.330	.347	.677
9	Dodgers	3,463	3,616	.489	7,158	243,765	30,092	64,582	10,018	3,148	2,240	26,757	20,253	1,415	24,026	5,142	271,716	87,616	15,406	6,283	854	.265	.325	.359	.684
10	Reds	3,452	3,656	.486	7,189	242,927	29,333	64,154	9,602	3,476	1,869	26,056	19,294	1,576	22,141	5,708	270,708	86,315	14,947	6,911	880	.264	.322	.355	.678
11	Red Sox	3,427	3,506	.494	7,006	237,039	30,402	62,772	10,807	3,096	2,166	27,039	21,780	1,532	23,462	4,603	267,423	86,269	16,069	7,072	964	.265	.331	.364	.695
12	Senators	3,340	3,594	.482	7,026	239,096	30,424	63,592	10,101	3,377	1,568	26,875	21,656	1,793	23,188	6,067	268,913	85,151	15,046	6,368	860	.266	.332	.356	.688
13	Athletics	3,332	3,570	.483	6,973	237,031	31,166	63,549	10,651	2,949	2,790	27,697	21,091	1,487	24,678	4,676	266,231	88,468	16,390	6,622	1,019	.268	.332	.373	.705
14	Browns	3,063	3,876	.441	7,033	238,206	29,828	62,569	10,339	2,812	2,384	26,456	21,687	1,375	25,707	4,790	267,749	85,684	15,535	6,481	882	.263	.328	.360	.687
15	Braves	3,023	4,048	.428	7,157	242,951	27,460	62,409	9,245	2,521	1,898	24,265	19,289	1,551	23,845	4,404	270,338	82,390	13,664	6,547	868	.257	.316	.339	.655
16	Phillies	2,993	4,072	.424	7,126	242,611	29,629	64,195	10,546	2,353	2,837	26,315	19,783	1,436	24,938	4,498	270,188	87,958	15,736	6,358	968	.265	.324	.363	.686
17	Whales	173	133	.565	312	10,231	1,262	2,634	412	127	102	1,102	964	71	1,200	332	11,614	3,606	641	348		.257	.326	.352	.678
18	Peppers	168	137	.551	312	10,273	1,347	2,757	440	170	50	1,116	908	72	1,160	457	11,678	3,687	660	425		.268	.332	.359	.691
19	Blues	154	149	.508	308	10,129	1,194	2,525	370	142	77	1,014	850	42	1,329	412	11,287	3,410	589	266		.249	.310	.337	.647
20	Rebels	150	153	.495	310	10,154	1,197	2,657	360	170	54	1,027	858	77	1,085	377	11,485	3,519	584	396		.262	.324	.347	.670
21	Terriers	149	156	.489	313	10,223	1,199	2,598	392	146	49	1,026	1,079	70	1,150	308	11,783	3,429	587	411		.254	.329	.335	.665
22	Packers	148	156	.487	307	10,064	1,191	2,575	426	143	67	1,040	767	82	1,091	315	11,264	3,488	636	351		.256	.314	.347	.660
23	Tip-Tops	147	159	.480	310	10,256	1,309	2,750	430	160	78	1,134	877	92	1,223	469	11,516	3,734	668	291		.268	.331	.364	.695
24	Terrapins	131	177	.425	314	10,180	1,195	2,609	418	120	68	1,016	957	83	1,184	280	11,579	3,471	606	359		.256	.325	.341	.666
25	Orioles	118	153	.435	276	9,349	1,476	2,666	381	218	57	1,231	786	106	797	396	10,459	3,654	656	218		.285	.347	.391	.738