Between the 2005 and 2018 seasons, the New York Yankees had the most wins by a team, with 1,296 wins.

Interpreted as:

MLB teams most regular-season wins from 2005 to 2018

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	1,296	972	.571	2,268	77,913	11,454	20,613	3,894	323	2,926	10,981	8,163	910	16,081	1,433	419	88,058	33,931	7,143	403	669	422	1,785	.265	.339	.435	.774
2	Red Sox	1,255	1,013	.553	2,268	78,737	11,515	21,264	4,694	360	2,567	10,943	8,204	796	16,205	1,276	380	88,738	34,379	7,621	296	705	589	1,882	.270	.342	.437	.779
3	Cardinals	1,246	1,021	.550	2,267	77,369	10,431	20,444	4,034	347	2,293	9,924	7,394	858	15,557	923	462	87,087	32,051	6,674	863	603	717	1,885	.264	.333	.414	.747
4	Dodgers	1,233	1,035	.544	2,268	77,007	10,001	19,954	3,918	417	2,170	9,493	7,694	769	16,231	1,359	549	86,877	31,216	6,505	828	579	662	1,794	.259	.330	.405	.736
5	Angels	1,225	1,043	.540	2,268	77,461	10,427	20,320	3,912	363	2,309	9,918	6,783	714	15,081	1,611	624	86,099	31,885	6,584	480	661	534	1,831	.262	.325	.412	.737
6	Indians	1,175	1,091	.519	2,266	77,533	10,562	20,180	4,307	356	2,398	10,086	7,673	871	16,680	1,304	460	87,222	32,393	7,061	475	670	442	1,728	.260	.331	.418	.749
7	Rangers	1,165	1,104	.513	2,269	78,032	11,070	20,659	4,098	390	2,717	10,536	6,951	822	16,535	1,436	521	86,940	33,688	7,205	496	639	416	1,698	.265	.329	.432	.761
8	Braves	1,157	1,110	.510	2,267	77,326	9,969	19,930	4,019	357	2,188	9,505	7,491	686	16,752	1,035	453	86,971	31,227	6,564	919	549	665	1,825	.258	.327	.404	.730
9	Phillies	1,153	1,115	.508	2,268	77,690	10,184	19,732	3,861	485	2,427	9,700	7,381	892	17,043	1,415	375	87,264	31,844	6,773	759	542	688	1,573	.254	.324	.410	.734
10	Tigers	1,149	1,118	.507	2,267	78,410	10,617	21,149	4,082	514	2,430	10,156	6,831	681	16,241	958	440	86,976	33,549	7,026	452	602	490	1,884	.270	.331	.428	.759
11	Athletics	1,149	1,118	.507	2,267	77,375	10,105	19,423	3,999	353	2,287	9,617	7,729	677	16,146	1,137	387	86,725	30,989	6,639	313	631	319	1,818	.251	.322	.401	.723
12	Brewers	1,144	1,125	.504	2,269	76,845	10,141	19,633	3,989	421	2,623	9,679	7,112	931	17,756	1,516	525	86,260	32,333	7,033	818	554	563	1,703	.255	.324	.421	.745
13	Cubs	1,143	1,123	.504	2,267	77,480	9,981	19,843	4,096	418	2,379	9,486	7,195	845	17,299	1,050	500	86,791	31,912	6,893	755	516	579	1,696	.256	.324	.412	.736
14	Rays	1,139	1,130	.502	2,269	76,868	10,042	19,504	3,871	472	2,463	9,575	7,566	885	17,694	1,712	645	86,386	31,708	6,806	409	658	389	1,615	.254	.325	.412	.738
15	Blue Jays	1,138	1,130	.502	2,268	77,503	10,550	19,895	4,220	316	2,730	10,072	7,326	758	15,971	1,091	416	86,604	32,937	7,266	378	639	334	1,855	.257	.324	.425	.749
16	Mets	1,134	1,134	.500	2,268	77,237	9,867	19,569	3,950	436	2,238	9,412	7,431	743	16,444	1,535	492	86,848	31,105	6,624	827	610	682	1,640	.253	.323	.403	.725
17	Nationals	1,129	1,137	.498	2,266	76,865	9,817	19,566	3,942	379	2,273	9,354	7,441	794	17,253	1,306	503	86,583	31,085	6,594	876	607	601	1,696	.255	.324	.404	.729
18	Giants	1,126	1,141	.497	2,267	77,337	9,307	19,830	3,952	534	1,790	8,811	6,559	628	15,479	1,140	482	85,984	30,220	6,276	831	629	633	1,823	.256	.317	.391	.708
19	Diamondbacks	1,103	1,165	.486	2,268	77,450	10,076	19,685	4,142	572	2,359	9,615	7,467	681	17,761	1,323	494	86,936	32,048	7,073	733	605	624	1,632	.254	.323	.414	.737
20	White Sox	1,100	1,169	.485	2,269	77,372	9,919	19,846	3,646	350	2,562	9,519	6,459	896	16,435	1,342	641	85,795	31,878	6,558	489	579	358	1,780	.257	.319	.412	.731
21	Twins	1,097	1,173	.483	2,270	77,853	10,254	20,285	4,002	461	2,061	9,718	7,261	639	15,892	1,251	488	86,863	31,392	6,524	468	642	482	1,802	.261	.326	.403	.729
22	Astros	1,086	1,181	.479	2,268	76,904	9,700	19,502	3,901	352	2,342	9,222	6,824	773	16,856	1,433	582	85,790	31,133	6,595	725	564	439	1,767	.254	.319	.405	.723
23	Rockies	1,080	1,190	.476	2,270	77,873	10,874	20,862	4,133	601	2,467	10,358	7,244	668	17,440	1,328	557	87,352	33,598	7,201	987	580	599	1,677	.268	.333	.431	.765
24	Reds	1,077	1,191	.475	2,269	77,250	10,021	19,629	3,883	341	2,539	9,554	7,462	827	17,337	1,410	542	87,051	31,811	6,763	936	576	610	1,595	.254	.324	.412	.736
25	Mariners	1,071	1,197	.472	2,268	77,570	9,357	19,636	3,671	339	2,219	8,875	6,283	713	16,224	1,277	503	85,575	30,642	6,229	478	531	463	1,688	.253	.313	.395	.708