Between the 2010 and 2024 seasons, Manny Machado had the most games with 2+ home runs, with 43 games.

Interpreted as:

most 2 or more hr regular-season games by a player from 2010 to 2024

	NAME	G	HR	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Manny Machado M. Machado	43	88	186	98	111	4	0	149	14	0	11	5	0	200	379	92	0	0	4	7	.597	.625	2.038	2.663
2	Aaron Judge A. Judge	39	80	151	90	94	5	0	133	25	1	23	0	1	179	339	85	0	2	3	1	.623	.670	2.245	2.915
3	Giancarlo Stanton G. Stanton	36	72	139	82	88	6	0	114	23	1	18	1	1	163	310	78	0	0	2	0	.633	.687	2.230	2.917
4	Nelson Cruz N. Cruz	35	72	155	79	96	9	1	139	6	0	25	0	0	161	323	82	0	0	1	1	.619	.634	2.084	2.717
5	Edwin Encarnacion E. Encarnacion	33	69	139	76	78	3	0	122	10	0	11	0	1	150	288	72	0	1	0	2	.561	.587	2.072	2.659
6	Albert Pujols A. Pujols	32	65	138	78	85	2	0	110	11	4	12	0	1	153	282	67	0	0	6	2	.616	.654	2.043	2.697
7	Kyle Schwarber K. Schwarber	31	65	130	74	78	4	1	112	19	1	25	0	2	150	279	70	0	0	1	1	.600	.653	2.146	2.799
8	Mookie Betts M. Betts	29	64	133	77	86	6	1	109	12	2	6	6	0	147	286	71	0	0	1	1	.647	.680	2.150	2.831
9	Miguel Cabrera M. Cabrera	29	60	123	73	87	8	0	101	9	1	9	0	0	134	275	68	0	1	4	1	.707	.724	2.236	2.960
10	Bryce Harper B. Harper	28	58	111	68	72	5	0	90	15	0	10	0	0	126	251	63	0	0	4	2	.649	.690	2.261	2.952
11	Paul Goldschmidt P. Goldschmidt	27	57	118	71	78	6	0	101	15	1	17	3	0	134	255	63	0	0	6	2	.661	.701	2.161	2.863
12	Jose Bautista J. Bautista	27	55	102	65	68	3	0	91	22	0	3	4	0	124	236	58	0	0	0	1	.667	.726	2.314	3.040
13	Khris Davis K. Davis	26	53	106	55	60	1	0	88	8	0	23	0	0	114	220	54	0	0	3	0	.566	.596	2.075	2.672
14	Mike Trout M. Trout	26	52	110	62	69	4	0	93	12	1	20	0	0	125	229	56	0	2	2	2	.627	.656	2.082	2.738
15	Matt Olson M. Olson	25	50	102	56	58	1	1	90	13	1	12	0	1	116	211	52	0	0	0	0	.569	.621	2.069	2.689
16	José Ramírez J. Ramírez	25	51	104	62	65	6	1	96	11	0	12	3	0	116	226	58	0	1	2	1	.625	.655	2.173	2.828
17	George Springer G. Springer	24	49	99	62	65	2	0	75	6	1	11	2	0	107	214	51	0	1	0	0	.657	.673	2.162	2.835
18	Nolan Arenado N. Arenado	24	49	109	53	64	6	0	90	4	1	13	0	0	114	217	55	0	0	1	4	.587	.605	1.991	2.596
19	Juan Soto J. Soto	23	47	99	52	61	3	0	81	11	0	12	0	0	110	205	50	0	0	1	3	.616	.655	2.071	2.725
20	J.D. Martinez	23	50	95	56	63	2	0	85	14	0	14	0	0	110	215	52	0	1	3	2	.663	.700	2.263	2.963
21	Josh Donaldson J. Donaldson	23	47	97	62	62	4	0	70	10	0	12	1	0	108	207	51	0	1	0	1	.639	.667	2.134	2.801
22	Ryan Braun R. Braun	23	48	100	55	60	3	1	85	7	0	10	3	0	108	209	52	0	1	1	0	.600	.620	2.090	2.710
23	Ryan Zimmerman R. Zimmerman	23	47	97	53	63	6	1	77	7	0	12	0	0	105	212	54	0	1	0	2	.649	.667	2.186	2.852
24	Jay Bruce J. Bruce	23	47	91	52	57	3	0	82	5	0	13	0	1	96	201	50	0	0	0	0	.626	.646	2.209	2.855
25	Yordan Alvarez Y. Alvarez	22	47	93	55	60	3	0	73	8	0	10	0	0	102	204	50	0	1	1	3	.645	.667	2.194	2.860