Babe Ruth has hit the most career homers when batting 3rd, with 553 home runs.

	NAME	HR	BAT ORDER	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Babe Ruth B. Ruth	553	3	1,746	6,119	1,645	2,113	348	90	1,625	1,574	29	974	84		7,795	4,300	991	73				.345	.481	.703	1.184
2	Ken Griffey Jr. K. Griffey Jr.	530	3	2,017	7,731	1,374	2,240	414	34	1,514	1,044	71	1,390	155	50	8,932	4,312	978	5	81	207	162	.290	.376	.558	.934
3	Albert Pujols A. Pujols	505	3	2,029	7,749	1,402	2,392	504	13	1,498	1,018	86	875	99	33	8,937	4,437	1,022	0	84	267	304	.309	.391	.573	.964
4	Hank Aaron H. Aaron	451	3	1,807	6,970	1,259	2,126	364	37	1,285	843	16	828	180	41	7,897	3,917	852	4	64	185	195	.305	.378	.562	.940
5	Willie Mays W. Mays	438	3	1,939	7,391	1,408	2,236	356	95	1,256	984	31	1,067	253	75	8,480	4,096	889	7	67	129	175	.303	.384	.554	.938
6	Frank Thomas F. Thomas	399	3	1,663	6,044	1,164	1,883	393	6	1,282	1,241	62	961	30	19	7,438	3,485	798	0	91	147	165	.312	.428	.577	1.005
7	Ted Williams T. Williams	388	3	1,541	5,446	1,296	1,870	352	39	1,289	1,445	31	500	19	4	6,940	3,464	779	1	17	79	158	.343	.482	.636	1.118
8	Stan Musial S. Musial	383	3	2,225	8,535	1,584	2,875	596	149	1,509	1,256	40	486	66	21	9,897	4,918	1,128	31	35	80	203	.337	.423	.576	.999
9	Gary Sheffield G. Sheffield	375	3	1,727	6,332	1,171	1,878	318	18	1,185	1,022	94	803	183	64	7,536	3,357	711	4	84	73	145	.297	.398	.530	.928
10	Jeff Bagwell J. Bagwell	361	3	1,620	5,999	1,187	1,770	389	23	1,198	1,109	97	1,215	169	66	7,280	3,288	773	0	75	126	178	.295	.409	.548	.957
11	Billy Williams B. Williams	354	3	1,958	7,679	1,193	2,280	366	77	1,215	825	33	821	75	39	8,603	3,862	797	5	61	142	171	.297	.365	.503	.868
12	Chipper Jones C. Jones	353	3	1,798	6,702	1,248	2,056	414	30	1,205	1,135	10	1,061	128	37	7,921	3,589	797	3	71	115	195	.307	.404	.536	.940
13	Barry Bonds B. Bonds	329	3	1,017	3,458	858	1,057	214	29	788	944	46	536	174	42	4,478	2,316	572	1	29	192	68	.306	.457	.670	1.127
14	Jose Canseco J. Canseco	322	3	1,224	4,728	818	1,272	217	11	969	586	63	1,296	158	75	5,429	2,477	550	1	51	49	128	.269	.354	.524	.878
15	Duke Snider D. Snider	312	3	1,291	5,007	948	1,526	267	59	954	672	13	833	82	38	5,749	2,847	638	31	26	64	118	.305	.387	.569	.955
16	Ryan Braun R. Braun	308	3	1,409	5,516	931	1,666	336	39	979	507	61	1,143	196	55	6,122	3,004	683	0	38	48	155	.302	.365	.545	.910
17	Eddie Mathews E. Mathews	293	3	1,225	4,516	851	1,263	201	44	822	822	13	750	45	24	5,411	2,431	538	23	37	50	66	.280	.389	.538	.928
18	Sammy Sosa S. Sosa	288	3	858	3,275	645	958	141	10	705	450	25	866	41	21	3,788	1,983	439	0	38	83	79	.293	.378	.605	.984
19	Carl Yastrzemski C. Yastrzemski	287	3	1,980	7,406	1,177	2,163	427	44	1,115	1,155	25	929	125	81	8,641	3,539	758	9	46	107	210	.292	.387	.478	.865
20	Mickey Mantle M. Mantle	287	3	1,264	4,463	916	1,324	184	41	754	945	11	951	77	24	5,456	2,451	512	11	26	59	67	.297	.419	.549	.968
21	Miguel Cabrera M. Cabrera	283	3	1,465	5,526	847	1,699	332	6	1,004	692	44	1,108	20	8	6,314	2,892	621	1	51	126	205	.307	.386	.523	.909
22	Alex Rodriguez A. Rodriguez	259	3	936	3,590	711	1,047	172	13	693	510	70	793	90	16	4,218	2,022	444	0	48	43	96	.292	.386	.563	.949
23	Bryce Harper B. Harper	251	3	1,179	4,246	793	1,204	293	10	731	795	38	1,092	98	28	5,131	2,270	554	4	48	113	103	.284	.397	.535	.932
24	George Brett G. Brett	250	3	1,907	7,349	1,151	2,266	486	91	1,207	848	24	668	138	60	8,324	3,684	827	6	97	185	192	.308	.377	.501	.879
25	David Ortiz D. Ortiz	249	3	968	3,658	640	1,050	253	9	776	640	20	728	6	2	4,362	2,068	511	1	43	103	103	.287	.392	.565	.957