Eddie Collins has scored the most career runs by a second baseman, with 1,818 runs.

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Eddie Collins E. Collins	1,818	2,794	9,902	3,303	438	186	47	1,298	1,497	77	461	740		11,984	4,254	671	508				.334	.425	.430	.855	2028	694.9	.410	144	621.4
2	Charlie Gehringer C. Gehringer	1,775	2,323	8,860	2,839	574	146	184	1,427	1,186	50	372	181		10,237	4,257	904	141			27	.320	.404	.480	.884	1797	516.6	.405	124	350
3	Bid McPhee B. McPhee	1,684	2,138	8,304	2,258	303	189	53	935	982	69	260	568		9,429	3,098	545	56				.272	.355	.373	.728	1594	183	.350	108	117.7
4	Joe Morgan J. Morgan	1,650	2,649	9,277	2,517	449	96	268	1,133	1,865	40	1,015	689	162	11,329	3,962	813	51	96	76	105	.271	.392	.427	.819	1717	490	.372	135	447.2
5	Roberto Alomar R. Alomar	1,508	2,379	9,073	2,724	504	80	210	1,134	1,032	50	1,140	474	114	10,400	4,018	794	148	97	62	206	.300	.371	.443	.814	1526	275.7	.359	118	230.8
6	Craig Biggio C. Biggio	1,432	2,058	7,948	2,262	503	44	228	897	901	232	1,300	328	97	9,216	3,537	775	68	67	51	117	.285	.371	.445	.816	1361	224.9	.360	119	221.1
7	Lou Whitaker L. Whitaker	1,386	2,390	8,570	2,369	420	65	244	1,084	1,197	20	1,099	143	75	9,967	3,651	729	89	91	79	143	.276	.363	.426	.789	1388	254.5	.353	118	208.3
8	Nap Lajoie N. Lajoie	1,325	2,224	8,554	2,874	585	132	67	1,370	474	118	296	340		9,352	3,924	784	206				.336	.379	.459	.838	1564	532.9	.399	145	486.2
9	Rogers Hornsby R. Hornsby	1,292	1,649	6,060	2,283	457	117	272	1,295	842	27	478	76		7,098	3,790	846	169				.377	.455	.625	1.080	1668	787.3	.484	182	756.9
10	Nellie Fox N. Fox	1,276	2,346	9,191	2,652	353	112	35	789	719	141	214	76	75	10,307	3,334	500	208	48	24	174	.289	.348	.363	.711	1183	3.9	.326	96	-52.1
11	Frankie Frisch F. Frisch	1,265	1,928	7,552	2,380	399	105	82	1,019	634	27	212	315		8,398	3,235	586	185				.315	.370	.428	.799	1222	174.5	.369	111	127.4
12	Robinson Cano R. Cano	1,262	2,267	8,773	2,639	572	33	335	1,306	620	85	1,214	51	38	9,550	4,282	940	10	62	112	286	.301	.351	.488	.839	1411	291.8	.358	124	273.3
13	Ray Durham R. Durham	1,249	1,975	7,408	2,054	440	79	192	875	820	72	1,201	273	97	8,423	3,228	711	55	68	34	151	.277	.352	.436	.788	1142	91.5	.345	105	57.4
14	Ian Kinsler I. Kinsler	1,243	1,888	7,423	1,999	416	41	257	909	693	92	1,046	243	74	8,299	3,268	714	32	59	11	161	.269	.337	.440	.777	1093	125.8	.338	107	69.9
15	Willie Randolph W. Randolph	1,239	2,202	8,018	2,210	316	65	54	687	1,243	38	675	271	94	9,462	2,818	435	99	64	37	219	.276	.373	.351	.724	1181	119.4	.335	110	108.3
16	Jose Altuve J. Altuve	1,236	1,976	7,881	2,388	455	32	255	889	655	80	1,139	325	96	8,696	3,672	742	27	53	50	215	.303	.360	.466	.826	1304	289.5	.355	129	294.8
17	Cupid Childs C. Childs	1,214	1,457	5,622	1,721	205	101	20	743	991	63	228	269		6,766	2,188	326	90				.306	.416	.389	.805	1303	293.6	.396	123	243.3
18	Ryne Sandberg R. Sandberg	1,213	1,995	7,744	2,213	370	71	275	1,007	725	30	1,169	312	95	8,589	3,550	716	24	66	56	132	.286	.347	.458	.805	1214	225.7	.355	117	165.6
19	Jeff Kent J. Kent	1,207	2,068	7,756	2,264	512	44	354	1,413	743	116	1,368	86	53	8,717	3,926	910	9	93	60	211	.292	.359	.506	.865	1370	289.2	.370	124	276.1
20	Billy Herman B. Herman	1,163	1,922	7,707	2,345	486	82	47	839	737	26	428	67		8,641	3,136	615	171			98	.304	.367	.407	.774	1195	163.5	.361	115	154.4
21	Red Schoendienst R. Schoendienst	1,134	2,073	7,909	2,292	405	72	83	726	585	20	328	63	27	8,619	3,090	560	86	19	15	174	.290	.340	.391	.730	1014	22.6	.335	95	-52.1
22	Chase Utley C. Utley	1,103	1,937	6,857	1,885	411	58	259	1,025	724	204	1,193	154	22	7,863	3,189	728	6	72	62	93	.275	.358	.465	.823	1145	219.7	.356	118	180.3
23	Bobby Doerr B. Doerr	1,094	1,865	7,093	2,042	381	89	223	1,247	809	11	608	54	1	8,028	3,270	693	115			187	.288	.362	.461	.823	1199	272.7	.380	115	143.5
24	Fred Pfeffer F. Pfeffer	1,062	1,575	6,185	1,595	223	116	93	827	521	21	154	381		6,747	2,329	432	20				.258	.318	.377	.694	1031	16.1	.327	94	-70.2
25	Chuck Knoblauch C. Knoblauch	1,025	1,415	5,545	1,646	293	61	83	549	718	121	625	350	105	6,449	2,310	437	13	52	20	101	.297	.386	.417	.803	954	163.5	.361	114	122.4