Jesse Orosco had the most games pitched when allowing exactly 0 earned runs, with 972 games.

Interpreted as:

most regular-season games by a player with 0 earned runs

	NAME	G	ER	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Jesse Orosco J. Orosco	972	0	73	5	.936	0	0.00	909	0	0	133	968.0	468	23	0	356	26	409	52	3,672	28	8.45	3.31	2.55	0.00	24.8	9.7	0.85	.197	0.21	4.35
2	Mariano Rivera M. Rivera	909	0	57	5	.919	1	0.00	941	0	0	602	1008.1	485	10	0	175	29	813	14	3,653	5	8.40	1.56	5.38	0.00	25.8	4.8	0.65	.193	0.09	4.33
3	Mike Stanton M. Stanton	878	0	63	3	.955	1	0.00	689	0	0	74	858.2	476	20	0	235	19	286	36	3,218	21	7.22	2.46	2.93	0.00	21.4	7.3	0.83	.209	0.21	4.99
4	John Franco J. Franco	865	0	68	8	.895	0	0.00	764	0	0	383	957.0	565	40	0	301	10	613	44	3,664	32	7.18	2.83	2.54	0.00	20.9	8.2	0.90	.218	0.38	5.31
5	Trevor Hoffman T. Hoffman	818	0	45	6	.882	0	0.00	933	0	0	553	864.1	383	18	1	181	1	706	25	3,124	26	9.72	1.88	5.15	0.01	29.9	5.8	0.65	.190	0.19	3.99
6	Dan Plesac D. Plesac	805	0	50	5	.909	3	0.00	761	0	0	149	767.1	386	26	2	232	8	344	25	2,873	19	8.93	2.72	3.28	0.02	26.5	8.1	0.81	.205	0.30	4.53
7	Mike Timlin M. Timlin	769	0	63	2	.969	2	0.00	625	0	0	128	872.2	481	21	1	184	31	357	30	3,214	16	6.45	1.90	3.40	0.01	19.4	5.7	0.76	.202	0.22	4.96
8	Kent Tekulve K. Tekulve	768	0	80	12	.870	0	0.00	583	0	0	165	1025.2	593	44	0	277	9	481	97	3,859	14	5.12	2.43	2.10	0.00	15.1	7.2	0.85	.198	0.39	5.20
9	Roberto Hernandez R. Hernandez	759	0	49	5	.907	0	0.00	726	0	0	293	800.1	454	38	0	264	23	518	28	3,068	26	8.16	2.97	2.75	0.00	23.7	8.6	0.90	.221	0.43	5.11
10	Kenley Jansen K. Jansen	758	0	43	0	1.000	0	0.00	1,075	0	0	427	767.0	286	10	0	188	24	587	11	2,785	12	12.61	2.21	5.72	0.00	38.6	6.8	0.62	.191	0.12	3.36
11	Francisco Rodriguez F. Rodriguez	748	0	35	3	.921	0	0.00	918	0	0	391	771.0	335	15	0	259	12	556	27	2,868	42	10.72	3.02	3.54	0.00	32.0	9.0	0.77	.200	0.18	3.91
12	Lee Smith L. Smith	748	0	47	5	.904	0	0.00	921	0	0	436	927.2	473	25	1	260	6	635	43	3,445	21	8.94	2.52	3.54	0.01	26.7	7.5	0.79	.209	0.24	4.59
13	Michael Jackson M. Jackson	739	0	53	6	.898	0	0.00	727	0	0	128	848.1	427	25	0	245	31	337	35	3,172	19	7.71	2.60	2.97	0.00	22.9	7.7	0.79	.197	0.27	4.53
14	LaTroy Hawkins L. Hawkins	728	0	42	5	.894	3	0.00	546	0	0	116	745.1	462	26	1	155	6	292	11	2,782	23	6.59	1.87	3.52	0.01	19.6	5.6	0.83	.222	0.31	5.58
15	Todd Jones T. Jones	723	0	48	1	.980	0	0.00	657	0	0	282	799.1	433	24	0	251	22	487	30	3,015	16	7.40	2.83	2.62	0.00	21.8	8.3	0.86	.208	0.27	4.88
16	Mike Myers M. Myers	711	0	25	1	.962	0	0.00	344	0	0	14	437.1	244	15	1	167	27	167	20	1,698	7	7.08	3.44	2.06	0.02	20.3	9.8	0.94	.210	0.31	5.02
17	Aroldis Chapman A. Chapman	709	0	52	2	.963	0	0.00	1,149	0	0	333	699.2	223	16	0	256	22	477	2	2,562	41	14.78	3.29	4.49	0.00	44.8	10.0	0.68	.196	0.21	2.87
18	Javier Lopez J. Lopez	707	0	30	2	.938	0	0.00	315	0	0	14	457.1	254	21	0	155	17	141	24	1,738	11	6.20	3.05	2.03	0.00	18.1	8.9	0.89	.203	0.41	5.00
19	David Robertson D. Robertson	706	0	58	1	.983	1	0.00	970	0	0	167	729.0	316	8	1	234	16	292	17	2,703	36	11.98	2.89	4.15	0.01	35.9	8.7	0.75	.213	0.10	3.90
20	Fernando Rodney F. Rodney	705	0	38	7	.844	0	0.00	733	0	0	289	704.1	323	26	0	251	27	460	10	2,658	26	9.37	3.21	2.92	0.00	27.6	9.4	0.81	.196	0.33	4.13
21	Hoyt Wilhelm H. Wilhelm	704	0	106	15	.876	9	0.00	970	7	5	197	1303.2	602	76	2	382	31	494	28	4,814	44	6.70	2.64	2.54	0.01	20.1	7.9	0.75	.175	0.52	4.16
22	Joe Smith J. Smith	703	0	47	0	1.000	0	0.00	562	0	0	30	635.1	333	14	0	156	31	147	20	2,350	15	7.96	2.21	3.60	0.00	23.9	6.6	0.77	.208	0.20	4.72
23	Billy Wagner B. Wagner	699	0	34	1	.971	0	0.00	988	0	0	392	738.0	300	24	2	197	22	600	14	2,705	30	12.05	2.40	5.02	0.02	36.5	7.3	0.67	.199	0.29	3.66
24	Craig Kimbrel C. Kimbrel	695	0	43	9	.827	0	0.00	1,082	0	0	414	684.0	253	17	0	215	29	566	4	2,514	38	14.24	2.83	5.03	0.00	43.0	8.6	0.68	.213	0.22	3.33
25	Jose Mesa J. Mesa	685	0	42	4	.913	7	0.00	602	2	2	288	772.2	462	34	2	227	18	492	20	2,961	26	7.01	2.64	2.65	0.02	20.3	7.7	0.89	.218	0.40	5.38