Between the 2000 and 2019 seasons, Albert Pujols had the most games with 2+ home runs, with 59 games.

Interpreted as:

most regular-season games by a player with 2 or more hr from 2000 to 2019

	NAME	G	HR	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Albert Pujols A. Pujols	59	122	245	143	156	6	0	212	29	6	20	1	0	281	528	128	0	1	10	4	.637	.680	2.155	2.835
2	David Ortiz D. Ortiz	51	102	218	119	134	10	0	175	14	0	19	0	0	233	450	112	0	1	5	0	.615	.635	2.064	2.699
3	Alex Rodriguez A. Rodriguez	50	105	216	131	133	6	0	204	25	3	24	3	2	245	454	111	0	1	1	4	.616	.657	2.102	2.759
4	Mark Teixeira M. Teixeira	42	87	187	96	112	9	1	171	14	1	28	1	0	203	384	97	0	1	1	3	.599	.626	2.053	2.679
5	Miguel Cabrera M. Cabrera	39	80	165	98	115	10	0	136	13	1	11	0	0	180	365	90	0	1	5	3	.697	.717	2.212	2.929
6	Vladimir Guerrero V. Guerrero	38	76	161	83	105	8	1	133	6	0	9	1	2	169	343	85	0	2	3	3	.652	.657	2.130	2.787
7	Alfonso Soriano A. Soriano	37	77	167	88	100	8	0	132	8	0	20	2	2	176	339	85	0	1	2	5	.599	.614	2.030	2.644
8	Carlos Beltran C. Beltran	37	75	162	82	98	4	2	136	15	1	19	5	0	180	331	81	0	2	2	3	.605	.633	2.043	2.677
9	Jim Thome J. Thome	37	75	146	86	90	9	0	132	24	0	24	1	0	172	324	84	0	2	5	1	.616	.663	2.219	2.882
10	Edwin Encarnacion E. Encarnacion	36	75	151	82	84	3	0	132	10	0	10	0	1	162	312	78	0	1	0	3	.556	.580	2.066	2.646
11	Adam Dunn A. Dunn	36	73	148	79	90	5	0	136	14	0	33	1	0	162	314	78	0	0	2	1	.608	.642	2.122	2.764
12	Manny Ramirez M. Ramirez	36	72	157	87	99	7	0	139	15	0	22	0	0	173	322	79	0	1	0	3	.631	.659	2.051	2.710
13	Andruw Jones A. Jones	35	72	147	79	88	4	0	125	10	1	17	2	0	159	308	76	0	1	2	1	.599	.623	2.095	2.718
14	Nelson Cruz N. Cruz	34	70	146	74	91	6	1	134	7	0	23	1	0	153	309	77	0	0	1	1	.623	.641	2.116	2.757
15	Ryan Braun R. Braun	33	68	141	77	84	4	1	116	10	0	12	3	0	152	294	73	0	1	1	1	.596	.618	2.085	2.704
16	Adrian Beltre A. Beltre	33	67	142	74	94	6	1	109	7	0	8	2	0	150	303	74	0	1	1	1	.662	.673	2.134	2.807
17	Giancarlo Stanton G. Stanton	32	64	123	72	78	5	0	98	21	1	17	1	1	145	275	69	0	0	2	0	.634	.690	2.236	2.925
18	Carlos Delgado C. Delgado	32	68	136	78	79	3	1	124	14	2	16	0	0	154	288	72	0	2	5	1	.581	.617	2.118	2.735
19	Jason Giambi J. Giambi	31	63	117	66	77	4	0	109	15	1	17	0	0	134	270	67	0	1	1	0	.658	.694	2.308	3.002
20	Sammy Sosa S. Sosa	30	64	121	68	77	2	0	106	12	0	13	0	0	134	271	66	0	1	3	1	.636	.664	2.240	2.904
21	Jose Bautista J. Bautista	29	59	110	70	72	3	0	98	23	0	3	4	0	133	252	62	0	0	0	2	.655	.714	2.291	3.005
22	Ryan Howard R. Howard	29	59	117	66	73	4	3	110	13	3	22	0	1	133	260	66	0	0	5	0	.624	.669	2.222	2.891
23	Barry Bonds B. Bonds	29	61	100	71	73	3	0	100	24	0	9	1	0	125	259	64	0	1	7	1	.730	.776	2.590	3.366
24	Jay Bruce J. Bruce	28	57	110	62	69	3	1	102	7	0	13	0	1	117	245	61	0	0	0	0	.627	.650	2.227	2.877
25	Mark Reynolds M. Reynolds	28	56	122	62	70	2	1	95	5	0	22	1	0	127	242	59	0	0	0	1	.574	.591	1.984	2.574

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Some of the information used here was obtained free of charge from Retrosheet.

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Cardinals	59	59	.500	15.0
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DATE	MATCHUP			TIME (ET)
Tue 8/11	PHI	@	STL	7:45 PM
Wed 8/12	PHI	@	STL	2:15 PM
Fri 8/14	STL	@	CHC	2:20 PM
Sat 8/15	STL	@	CHC	2:20 PM
Sun 8/16	STL	@	CHC	3:15 PM

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Final

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Marlins	60	59	.504	11.5
Nationals	59	61	.492	13.0
Mets	52	67	.437	19.5
NL Central	W	L	PCT	GB
Brewers	74	44	.627
Cubs	69	50	.580	5.5
Cardinals	59	59	.500	15.0
Pirates	58	62	.483	17.0
Reds	56	61	.479	17.5
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Red Sox	64	53	.547	7.0
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White Sox	61	56	.521
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Twins	58	61	.487	4.0
Guardians	58	61	.487	4.0
Royals	49	70	.412	13.0
AL West	W	L	PCT	GB
Astros	60	59	.504
Rangers	59	59	.500	0.5
Mariners	56	63	.471	4.0
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