Hank Aaron had the most games when collecting 2+ RBI, with 590 games.

Interpreted as:

most regular-season games by a player with a 2 or more rbi

	NAME	G	RBI	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Hank Aaron H. Aaron	590	1,515	2,409	782	1,155	151	33	497	254	4	202	39	11	2,712	2,863	681	0	45	59	38	.479	.521	1.188	1.709
2	Albert Pujols A. Pujols	569	1,471	2,300	757	1,111	210	7	448	243	21	198	24	13	2,609	2,679	665	0	45	67	62	.483	.527	1.165	1.692
3	Babe Ruth B. Ruth	529	1,444	2,026	850	1,033	144	50	465	449	7	229	27		2,515	2,672	659	33				.510	.600	1.319	1.919
4	Alex Rodriguez A. Rodriguez	528	1,395	2,171	766	1,037	167	10	458	262	27	339	70	12	2,505	2,598	635	1	44	26	40	.478	.530	1.197	1.726
5	Lou Gehrig L. Gehrig	515	1,415	2,107	777	1,078	186	68	364	336	9	129	32		2,481	2,492	618	29				.512	.580	1.183	1.763
6	Barry Bonds B. Bonds	507	1,311	1,838	743	953	146	29	463	413	19	197	96	25	2,308	2,546	638	0	38	107	31	.518	.600	1.385	1.985
7	Stan Musial S. Musial	502	1,252	2,056	650	1,064	178	70	321	264	8	83	18	8	2,348	2,345	569	1	19	21	33	.518	.569	1.141	1.710
8	Jimmie Foxx J. Foxx	500	1,349	1,982	715	968	152	47	395	319	2	225	18		2,328	2,399	594	25			10	.488	.560	1.210	1.770
9	Manny Ramirez M. Ramirez	494	1,306	1,934	666	952	172	7	404	261	16	332	7	6	2,256	2,350	583	1	44	36	42	.492	.545	1.215	1.760
10	Willie Mays W. Mays	487	1,214	2,007	716	987	118	57	419	191	7	183	73	19	2,234	2,476	594	1	28	24	35	.492	.531	1.234	1.764
11	Mel Ott M. Ott	484	1,264	1,905	676	933	140	30	358	314	10	126	20		2,248	2,207	528	19			2	.490	.564	1.159	1.722
12	Ken Griffey Jr. K. Griffey Jr.	480	1,234	1,948	631	888	158	13	415	207	14	263	38	12	2,205	2,317	586	1	35	48	24	.456	.503	1.189	1.693
13	Al Simmons A. Simmons	479	1,247	2,112	597	1,051	203	65	227	123	9	111	28		2,278	2,065	495	34			1	.498	.527	.978	1.505
14	Eddie Murray E. Murray	478	1,222	1,933	559	908	154	13	325	204	3	183	18	4	2,175	2,063	492	0	35	31	33	.470	.513	1.067	1.580
15	Ted Williams T. Williams	475	1,264	1,824	688	923	162	25	357	422	6	119	8	1	2,260	2,206	544	3	5	17	34	.506	.599	1.209	1.808
16	Carl Yastrzemski C. Yastrzemski	469	1,143	1,852	540	888	166	11	304	242	6	149	34	12	2,134	1,988	481	2	32	30	31	.479	.533	1.073	1.606
17	Miguel Cabrera M. Cabrera	466	1,214	1,906	573	974	189	5	345	184	10	271	9	8	2,142	2,208	539	1	41	37	43	.511	.546	1.158	1.704
18	David Ortiz D. Ortiz	460	1,197	1,828	562	871	204	10	354	236	9	260	2	0	2,109	2,157	568	0	36	46	32	.476	.529	1.180	1.709
19	Rafael Palmeiro R. Palmeiro	451	1,141	1,818	541	878	156	12	337	198	11	181	11	7	2,072	2,069	505	0	45	22	31	.483	.525	1.138	1.663
20	Dave Winfield D. Winfield	447	1,140	1,835	521	849	127	26	293	177	11	219	32	21	2,061	1,907	446	4	34	37	42	.463	.504	1.039	1.543
21	Jim Thome J. Thome	444	1,125	1,668	596	777	133	7	382	298	7	381	1	4	1,996	2,070	522	0	23	42	24	.466	.542	1.241	1.783
22	Frank Robinson F. Robinson	443	1,139	1,745	623	866	136	22	369	208	26	188	47	13	2,015	2,153	527	2	34	38	33	.496	.546	1.234	1.780
23	Harmon Killebrew H. Killebrew	439	1,093	1,635	544	741	79	9	387	270	11	247	5	5	1,950	1,999	475	0	34	26	42	.453	.524	1.223	1.747
24	Frank Thomas F. Thomas	433	1,115	1,697	544	819	168	7	322	263	12	217	5	4	2,023	1,967	497	0	51	30	37	.483	.541	1.159	1.700
25	Reggie Jackson R. Jackson	432	1,097	1,700	531	786	121	13	361	192	17	300	36	14	1,928	2,016	495	1	18	20	23	.462	.516	1.186	1.702