Yu Darvish and Joe Musgrove were tied for starting the most games for the Padres in 2022, with 30 starts.

	NAME	GS	SEASON	TM	G	W	L	W%	ERA	SO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Yu Darvish Y. Darvish	30	2022	SDP	30	16	8	.667	3.10	197	0	194.2	148	67	67	22	37	12	0	0	771	4	9.11	1.71	5.32	1.02	25.6	4.8	0.95	.250	3.10	81	3.31	84	6.84	13.9
2	Joe Musgrove J. Musgrove	30	2022	SDP	30	10	7	.588	2.93	184	0	181.0	154	59	67	22	42	14	0	1	740	4	9.15	2.09	4.38	1.09	24.9	5.7	1.08	.276	3.33	77	3.58	91	7.66	7.3
3	Sean Manaea S. Manaea	28	2022	SDP	30	8	9	.471	4.96	156	0	158.0	155	87	95	29	50	3	1	1	671	0	8.89	2.85	3.12	1.65	23.2	7.5	1.30	.291	5.41	130	4.52	115	8.83	-10.3
4	Blake Snell B. Snell	24	2022	SDP	24	8	10	.444	3.38	171	0	128.0	103	48	51	11	51	2	0	0	535	6	12.02	3.59	3.35	0.77	32.0	9.5	1.20	.307	3.59	89	2.79	71	7.24	16.5
5	Mike Clevinger M. Clevinger	22	2022	SDP	23	7	7	.500	4.33	91	0	114.1	102	55	56	20	35	10	0	0	485	3	7.16	2.76	2.60	1.57	18.8	7.2	1.20	.249	4.41	114	4.97	126	8.03	-13.2
6	MacKenzie Gore M. Gore	13	2022	SDP	16	4	4	.500	4.50	72	0	70.0	66	35	35	7	37	4	0	0	309	6	9.26	4.76	1.95	0.90	23.3	12.0	1.47	.312	4.50	118	4.11	104	8.49	-1.3
7	Nick Martinez N. Martinez	10	2022	SDP	47	4	4	.500	3.47	95	8	106.1	96	41	44	15	41	4	15	0	448	4	8.04	3.47	2.32	1.27	21.2	9.2	1.29	.276	3.72	91	4.42	112	8.13	-5.7
8	Nabil Crismatt N. Crismatt	1	2022	SDP	50	5	2	.714	2.94	65	0	67.1	57	22	29	5	22	2	14	1	280	0	8.69	2.94	2.95	0.67	23.2	7.9	1.17	.280	3.88	77	3.21	81	7.62	5.5
9	Craig Stammen C. Stammen	1	2022	SDP	33	1	2	.333	4.43	35	0	40.2	45	20	22	9	10	2	9	0	177	3	7.75	2.21	3.50	1.99	19.8	5.6	1.35	.298	4.87	116	5.15	130	9.96	-5.5
10	Steven Wilson S. Wilson	1	2022	SDP	50	4	2	.667	3.06	53	1	53.0	36	18	20	7	20	3	8	0	214	4	9.00	3.40	2.65	1.19	24.8	9.3	1.06	.221	3.40	80	4.13	105	6.11	-1.1
11	Ryan Weathers R. Weathers	1	2022	SDP	1	0	0		9.82	3	0	3.2	6	4	4	0	4	0	0	0	21	0	7.36	9.82	0.75	0.00	14.3	19.0	2.73	.429	9.82	258	4.74	120	14.73	-0.3
12	Reiss Knehr R. Knehr	1	2022	SDP	5	0	0		3.95	10	0	13.2	11	6	6	1	4	4	2	0	59	0	6.59	2.63	2.50	0.66	16.9	6.8	1.10	.250	3.95	104	4.35	110	7.24	-0.6