Ty Cobb has gotten the most career hits against the Yankees, with 619 hits.

Interpreted as:

most hits by a player against the yankees career

	NAME	H	G	AB	R	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Ty Cobb T. Cobb	619	443	1,660	342	117	53	23		176	11		103		1,884	911	193	37				.373	.436	.549	.985
2	Tristram Speaker T. Speaker	499	410	1,517	284	120	24	27		185	13		66		1,762	748	171	47				.329	.406	.493	.899
3	Eddie Collins E. Collins	489	403	1,429	281	69	27	12		196	8		100		1,699	648	108	66				.342	.424	.453	.878
4	Charlie Gehringer C. Gehringer	420	344	1,301	251	74	23	33	195	194	2	71	19		1,509	639	130	12			6	.323	.411	.491	.903
5	Sam Rice S. Rice	414	351	1,327	208	81	31	10		93	12	37	43		1,462	587	122	30				.312	.362	.442	.805
6	Al Kaline A. Kaline	380	345	1,215	199	60	9	39	195	164	6	100	15	6	1,408	575	108	5	18	18	36	.313	.392	.473	.865
7	Luke Appling L. Appling	380	351	1,260	184	57	11	8	147	211	1	76	20		1,480	483	76	8			18	.302	.402	.383	.786
8	Harry Heilmann H. Heilmann	379	290	1,081	175	53	37	20		102	2	83	16		1,232	566	110	47				.351	.408	.524	.931
9	Goose Goslin G. Goslin	375	334	1,266	205	64	30	46	227	121	4	109	19		1,409	637	140	18				.296	.359	.503	.863
10	Al Simmons A. Simmons	374	304	1,202	188	72	12	45	231	81	7	143	9		1,311	605	129	21			2	.311	.358	.503	.861
11	Doc Cramer D. Cramer	372	331	1,320	193	46	14	8	96	91	6	64	6		1,442	470	68	25			25	.282	.331	.356	.687
12	Sam Crawford S. Crawford	363	305	1,139	189	45	48	14		94	3		47		1,275	546	107	39				.319	.372	.479	.852
13	Heinie Manush H. Manush	359	264	1,053	207	71	19	19	154	59	5	57	17		1,142	525	109	25				.341	.379	.499	.877
14	Ted Williams T. Williams	357	327	1,035	225	72	7	62	229	309	3	99	2	2	1,351	629	141	0	4	12	39	.345	.495	.608	1.103
15	Carl Yastrzemski C. Yastrzemski	352	329	1,243	182	50	13	52	163	155	2	143	18	10	1,411	584	115	2	9	26	36	.283	.361	.470	.831
16	Joe Judge J. Judge	340	328	1,203	178	56	35	20		150	11	86	23		1,397	526	111	33				.283	.367	.437	.805
17	Jimmie Foxx J. Foxx	326	302	1,077	195	45	20	70	246	173	2	190	10		1,260	621	135	8			10	.303	.400	.577	.977
18	Nellie Fox N. Fox	322	303	1,178	139	39	16	7	99	103	21	38	8	9	1,315	414	62	11	2	2	31	.273	.342	.351	.693
19	George Sisler G. Sisler	320	243	974	144	41	16	19		56	5	35	39		1,059	450	76	24				.329	.368	.462	.830
20	Joe Cronin J. Cronin	319	291	1,046	164	59	22	30	193	141	3	105	10		1,218	512	111	28			6	.305	.389	.489	.879
21	Clyde Milan C. Milan	315	291	1,084	153	40	11	4		101	10		60		1,217	389	55	22				.291	.356	.359	.715
22	Harry Hooper H. Hooper	313	324	1,221	207	47	21	20		155	9		54		1,415	462	88	30				.256	.344	.378	.723
23	Jimmy Dykes J. Dykes	308	333	1,193	145	52	17	23	147	142	14	157	12		1,377	463	92	28				.258	.344	.388	.732
24	Earl Averill E. Averill	307	247	950	177	51	16	41	174	106	7	97	11		1,070	513	108	7			2	.323	.395	.540	.935
25	Brooks Robinson B. Robinson	306	328	1,173	131	49	6	34	154	84	2	86	2	3	1,283	469	89	13	11	22	33	.261	.309	.400	.708