Between the 1920 and 1929 seasons, Lou Gehrig and Jim Bottomley were tied for the most home runs by a first baseman, with 146 home runs.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Lou Gehrig L. Gehrig	146	767	2,746	631	919	206	72	635	480	15	351	30		3,321	1,707	424	80	.335	.436	.622	1.058	743	327.2	.470	170	313.1
2	Jim Bottomley J. Bottomley	146	1,062	4,134	711	1,354	261	104	885	406	24	337	40		4,690	2,261	511	126	.328	.391	.547	.938	869	282.6	.422	140	248.9
3	Jack Fournier J. Fournier	121	1,059	3,748	621	1,213	186	69	657	424	61	256	78		4,340	1,900	376	107	.324	.401	.507	.908	778	243.1	.416	144	240.9
4	High Pockets Kelly H. Pockets Kelly	114	1,204	4,600	649	1,388	275	66	824	304	24	517	57		5,051	2,137	455	123	.302	.348	.465	.813	725	102.4	.371	115	94.4
5	Joe Hauser J. Hauser	80	629	2,044	351	580	103	28	356	250	21	229	19		2,370	979	211	55	.284	.368	.479	.847	371	78.9	.388	116	48.9
6	George Sisler G. Sisler	78	1,326	5,480	894	1,900	297	111	830	305	26	192	214		5,950	2,653	486	139	.347	.384	.484	.868	977	239.2	.398	119	146.1
7	Bill Terry B. Terry	72	760	2,639	432	861	157	42	476	241	3	213	26		2,949	1,318	271	66	.326	.383	.499	.883	499	127.6	.401	128	112.5
8	Wally Pipp W. Pipp	56	1,189	4,400	638	1,282	204	87	682	353	24	240	60		4,960	1,828	347	183	.291	.347	.415	.763	641	34.2	.354	100	-2.9
9	Charlie Grimm C. Grimm	53	1,458	5,389	627	1,570	257	87	748	395	19	274	48		5,971	2,160	397	168	.291	.342	.401	.743	732	-7.2	.345	94	-39
10	Joe Judge J. Judge	53	1,359	5,063	765	1,567	290	101	739	600	33	250	114		5,883	2,218	444	187	.310	.386	.438	.824	901	172.1	.383	117	132.2
11	Don Hurst D. Hurst	50	261	985	173	292	52	8	189	148	4	76	13		1,167	510	110	30	.296	.391	.518	.908	207	57.6	.409	119	31
12	Earl Sheely E. Sheely	47	1,087	3,933	542	1,193	229	25	668	529	38	184	33		4,677	1,613	301	177	.303	.391	.410	.801	696	108.8	.377	110	65.5
13	George Burns G. Burns	43	1,114	3,842	571	1,234	317	30	605	230	60	220	84		4,233	1,740	390	101	.321	.369	.453	.822	633	108.3	.379	110	59.5
14	Phil Todt P. Todt	41	784	2,835	300	729	147	51	348	175	23	174	24		3,141	1,101	239	108	.257	.306	.388	.694	320	-74	.319	76	-101.9
15	Lu Blue L. Blue	39	1,230	4,516	897	1,324	248	87	548	820	33	311	109		5,514	1,863	374	145	.293	.405	.413	.818	862	171.2	.386	115	112
16	Del Bissonette D. Bissonette	37	271	1,018	158	309	58	23	181	116	5	133	7		1,153	524	118	14	.304	.378	.515	.892	195	49.9	.402	126	38.8
17	Jimmie Foxx J. Foxx	36	210	647	146	225	29	14	138	117	3	81	11		784	390	79	17	.348	.450	.603	1.053	179	76.6	.467	167	71.9
18	Ray Grimes R. Grimes	27	433	1,537	269	505	101	25	263	204	17	133	21		1,788	737	153	30	.329	.413	.480	.892	316	93.4	.412	135	81.7
19	George Grantham G. Grantham	26	379	1,248	233	402	75	28	207	169	8	108	29		1,467	611	129	42	.322	.406	.490	.896	258	76.1	.412	132	61.1
20	Joe Harris J. Harris	26	462	1,478	246	461	97	37	265	222	19	86	14		1,773	710	160	54	.312	.408	.480	.889	310	89.5	.410	130	72.1
21	Dale Alexander D. Alexander	25	155	626	110	215	43	15	137	56	0	63	5	9	700	363	83	18	.343	.397	.580	.977	139	46.4	.431	143	40.9
22	Babe Herman B. Herman	25	267	908	129	270	61	20	154	83	2	94	12		1,020	446	106	27	.297	.358	.491	.849	158	33.8	.387	126	32.8
23	Jake Daubert J. Daubert	21	661	2,584	390	791	102	66	263	195	15	103	53		2,910	1,088	189	116	.306	.358	.421	.779	394	38.8	.362	112	44.3
24	Walter Holke W. Holke	21	798	2,968	307	858	106	39	344	120	4	183	29		3,203	1,105	166	111	.289	.318	.372	.690	328	-65.8	.321	79	-88.8
25	Frank Brower F. Brower	19	192	504	93	143	35	9	86	89	10	41	7		612	253	63	9	.284	.401	.502	.903	109	33.6	.416	133	26.9