Between the 2000 and 2021 seasons, David Ortiz crushed the most homers by a designated hitter, with 531 homers.
| NAME | HR | G | AB | R | H | 2B | 3B | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | wRC | WRAA | wOBA | wRC+ | BRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Ortiz | 531 | 2,297 | 8,293 | 1,361 | 2,379 | 609 | 19 | 1,716 | 1,273 | 33 | 1,647 | 16 | 9 | 9,689 | 4,619 | 1,159 | 2 | 88 | 206 | 225 | .287 | .380 | .557 | .937 | 1706 | 556 | .394 | 141 | 483.8 |
| 2 |  | N. Cruz | 248 | 926 | 3,429 | 537 | 961 | 158 | 5 | 656 | 374 | 58 | 876 | 11 | 7 | 3,895 | 1,873 | 411 | 0 | 34 | 48 | 98 | .280 | .358 | .546 | .904 | 661 | 199.6 | .378 | 143 | 203 |
| 3 |  | E. Encarnacion | 220 | 929 | 3,365 | 545 | 878 | 166 | 2 | 636 | 474 | 45 | 726 | 31 | 7 | 3,925 | 1,708 | 388 | 0 | 41 | 29 | 94 | .261 | .356 | .508 | .864 | 619 | 161.2 | .367 | 131 | 141.8 |
| 4 |  | F. Thomas | 220 | 951 | 3,307 | 526 | 904 | 178 | 2 | 664 | 591 | 46 | 656 | 4 | 5 | 3,983 | 1,746 | 400 | 0 | 39 | 35 | 74 | .273 | .387 | .528 | .915 | 697 | 202.3 | .391 | 136 | 186 |
| 5 |  | T. Hafner | 213 | 1,183 | 4,058 | 619 | 1,107 | 250 | 13 | 731 | 598 | 90 | 976 | 11 | 7 | 4,775 | 2,022 | 476 | 0 | 29 | 81 | 86 | .273 | .376 | .498 | .874 | 766 | 193.9 | .374 | 132 | 189.5 |
| 6 |  | J. Thome | 182 | 805 | 2,503 | 432 | 663 | 127 | 2 | 506 | 490 | 19 | 786 | 1 | 1 | 3,032 | 1,340 | 311 | 0 | 20 | 46 | 59 | .265 | .387 | .535 | .922 | 530 | 165.9 | .393 | 139 | 145.9 |
| 7 | | K. Morales | 154 | 980 | 3,550 | 413 | 933 | 185 | 3 | 536 | 306 | 35 | 748 | 2 | 4 | 3,916 | 1,586 | 342 | 0 | 25 | 23 | 125 | .263 | .325 | .447 | .772 | 502 | 53.8 | .332 | 110 | 46.8 |
| 8 | | V. Martinez | 115 | 969 | 3,558 | 405 | 1,033 | 188 | 0 | 540 | 319 | 25 | 409 | 4 | 4 | 3,942 | 1,566 | 303 | 0 | 40 | 67 | 131 | .290 | .349 | .440 | .789 | 521 | 73.7 | .339 | 113 | 56.4 |
| 9 |  | J.D. Martinez | 114 | 498 | 1,925 | 323 | 571 | 128 | 7 | 361 | 218 | 13 | 493 | 9 | 1 | 2,175 | 1,055 | 249 | 0 | 19 | 29 | 62 | .297 | .369 | .548 | .917 | 382 | 117.2 | .381 | 138 | 100.3 |
| 10 | | B. Butler | 111 | 1,097 | 3,902 | 437 | 1,107 | 226 | 4 | 557 | 373 | 27 | 659 | 4 | 3 | 4,336 | 1,674 | 341 | 0 | 34 | 48 | 155 | .284 | .348 | .429 | .777 | 564 | 70.5 | .337 | 110 | 52 |
| 11 | | E. Martinez | 111 | 668 | 2,337 | 339 | 689 | 142 | 1 | 481 | 406 | 29 | 456 | 9 | 3 | 2,805 | 1,166 | 254 | 0 | 33 | 42 | 62 | .295 | .401 | .499 | .900 | 481 | 130.8 | .386 | 138 | 137.6 |
| 12 | | A. Dunn | 108 | 553 | 1,908 | 232 | 385 | 68 | 0 | 288 | 327 | 15 | 747 | 4 | 4 | 2,263 | 777 | 176 | 0 | 13 | 15 | 25 | .202 | .321 | .407 | .728 | 266 | 15.1 | .322 | 101 | 0.9 |
| 13 |  | S. Ohtani | 93 | 409 | 1,400 | 236 | 370 | 73 | 15 | 247 | 188 | 8 | 451 | 55 | 18 | 1,603 | 752 | 181 | 0 | 7 | 23 | 18 | .264 | .353 | .537 | .890 | 267 | 71.6 | .370 | 134 | 67.2 |
| 14 | | B. Fullmer | 89 | 548 | 1,897 | 295 | 532 | 123 | 12 | 314 | 153 | 32 | 261 | 24 | 12 | 2,101 | 946 | 224 | 0 | 19 | 22 | 45 | .280 | .341 | .499 | .840 | 307 | 44.5 | .356 | 113 | 33.7 |
| 15 |  | E. Gattis | 84 | 409 | 1,420 | 173 | 343 | 56 | 11 | 238 | 106 | 10 | 347 | 3 | 2 | 1,554 | 673 | 151 | 0 | 18 | 11 | 38 | .242 | .295 | .474 | .769 | 191 | 11.4 | .324 | 107 | 13.5 |
| 16 | | J. Gomes | 84 | 514 | 1,543 | 232 | 370 | 70 | 10 | 231 | 195 | 43 | 517 | 33 | 16 | 1,803 | 712 | 164 | 2 | 20 | 7 | 20 | .240 | .338 | .461 | .799 | 246 | 27.2 | .345 | 113 | 26.8 |
| 17 | | D. Young | 82 | 487 | 1,793 | 255 | 500 | 100 | 13 | 267 | 143 | 28 | 379 | 6 | 3 | 1,975 | 872 | 195 | 0 | 11 | 32 | 55 | .279 | .340 | .486 | .826 | 278 | 36.5 | .350 | 115 | 36.7 |
| 18 |  | G. Stanton | 77 | 320 | 1,203 | 178 | 322 | 60 | 1 | 208 | 148 | 13 | 395 | 6 | 1 | 1,377 | 615 | 138 | 0 | 13 | 7 | 43 | .268 | .351 | .511 | .862 | 221 | 56.9 | .365 | 134 | 56 |
| 19 |  | K. Davis | 76 | 356 | 1,244 | 179 | 286 | 49 | 2 | 216 | 126 | 18 | 378 | 0 | 0 | 1,400 | 567 | 127 | 0 | 12 | 8 | 34 | .230 | .307 | .456 | .763 | 176 | 5.9 | .323 | 106 | 9.7 |
| 20 | | L. Scott | 75 | 446 | 1,463 | 193 | 376 | 90 | 5 | 244 | 165 | 14 | 345 | 8 | 1 | 1,658 | 701 | 170 | 0 | 16 | 13 | 27 | .257 | .335 | .479 | .814 | 231 | 39.4 | .350 | 117 | 33.5 |
| 21 | | H. Matsui | 72 | 555 | 1,887 | 225 | 500 | 91 | 2 | 298 | 233 | 9 | 326 | 1 | 3 | 2,144 | 811 | 165 | 0 | 15 | 17 | 39 | .265 | .346 | .430 | .776 | 280 | 31.1 | .340 | 110 | 26.3 |
| 22 |  | A. Pujols | 71 | 400 | 1,577 | 173 | 403 | 55 | 0 | 284 | 126 | 9 | 223 | 8 | 1 | 1,729 | 671 | 126 | 0 | 17 | 19 | 68 | .256 | .311 | .425 | .737 | 196 | -6.6 | .314 | 98 | -4.6 |
| 23 | | J. Cust | 71 | 479 | 1,555 | 225 | 386 | 75 | 2 | 238 | 320 | 10 | 588 | 6 | 5 | 1,898 | 678 | 148 | 0 | 13 | 9 | 22 | .248 | .377 | .436 | .813 | 280 | 54.5 | .361 | 124 | 55.7 |
| 24 | | M. Sweeney | 70 | 536 | 1,863 | 233 | 523 | 115 | 2 | 309 | 180 | 23 | 252 | 11 | 2 | 2,088 | 852 | 187 | 1 | 21 | 23 | 55 | .281 | .348 | .457 | .805 | 286 | 32.9 | .347 | 109 | 23.9 |
| 25 | | A. Huff | 70 | 418 | 1,602 | 231 | 478 | 107 | 7 | 239 | 138 | 5 | 231 | 9 | 2 | 1,758 | 809 | 184 | 0 | 13 | 16 | 39 | .298 | .353 | .505 | .858 | 270 | 56.4 | .367 | 124 | 51 |
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Braves - y | 92 | 64 | .590 | |
86 | 70 | .551 | 6.0 | |
76 | 80 | .487 | 16.0 | |
73 | 83 | .468 | 19.0 | |
71 | 85 | .455 | 21.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 98 | 58 | .628 | |
87 | 69 | .558 | 11.0 | |
79 | 77 | .506 | 19.0 | |
76 | 80 | .487 | 22.0 | |
72 | 84 | .462 | 26.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 96 | 60 | .615 | |
87 | 69 | .558 | 9.0 | |
82 | 74 | .526 | 14.0 | |
64 | 92 | .410 | 32.0 | |
57 | 99 | .365 | 39.0 |
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