most home runs by a pitcher 2000 to 2021

Between the 2000 and 2021 seasons, Bartolo Colon gave up the most home runs, with 388 HR.

	NAME	HR	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Bartolo Colon B. Colon	388	483	211	167	.558	472	4.11	2,150	30	10	0	2958.2	3,096	1,351	1,465	748	51	2	36	12,487	32	6.54	2.28	2.87	1.18	17.2	6.0	1.30	.296	4.46	96	4.14	97	9.42	44.8
2	CC Sabathia	382	561	251	161	.609	560	3.74	3,093	38	12	0	3577.1	3,404	1,485	1,623	1,099	123	0	44	14,989	74	7.78	2.76	2.81	0.96	20.6	7.3	1.26	.294	4.08	87	3.77	87	8.56	223.7
3	James Shields J. Shields	361	407	145	139	.511	405	4.01	2,234	23	9	0	2616.0	2,581	1,167	1,267	746	97	1	22	10,993	107	7.69	2.57	2.99	1.24	20.3	6.8	1.27	.294	4.36	98	4.16	101	8.88	-13.5
4	Mark Buehrle M. Buehrle	361	518	214	160	.572	493	3.81	1,870	33	10	0	3283.1	3,472	1,391	1,542	734	79	6	49	13,705	27	5.13	2.01	2.55	0.99	13.6	5.4	1.28	.292	4.23	87	4.11	93	9.52	111.9
5	Bronson Arroyo B. Arroyo	347	419	148	137	.519	383	4.28	1,571	16	6	1	2435.2	2,507	1,158	1,260	661	105	6	60	10,338	42	5.80	2.44	2.38	1.28	15.2	6.4	1.30	.282	4.66	100	4.59	108	9.26	-82
6	Ervin Santana E. Santana	331	425	151	129	.539	386	4.11	1,978	21	11	0	2486.2	2,391	1,135	1,221	776	104	20	35	10,482	104	7.16	2.81	2.55	1.20	18.9	7.4	1.27	.282	4.42	99	4.31	104	8.65	-44.1
7	Zack Greinke Z. Greinke	328	530	219	132	.624	488	3.41	2,809	17	5	1	3110.0	2,892	1,179	1,263	712	72	8	25	12,699	92	8.13	2.06	3.95	0.95	22.1	5.6	1.16	.292	3.65	81	3.43	83	8.37	244.3
8	Javier Vazquez J. Vazquez	322	391	151	137	.524	385	4.04	2,284	25	7	0	2513.0	2,434	1,129	1,212	643	73	4	52	10,504	72	8.18	2.30	3.55	1.15	21.7	6.1	1.22	.294	4.34	91	3.77	86	8.72	179
9	John Lackey J. Lackey	319	448	188	147	.561	446	3.92	2,294	18	8	0	2840.1	2,862	1,237	1,347	815	133	0	32	12,030	125	7.27	2.58	2.81	1.01	19.1	6.8	1.29	.300	4.27	92	3.94	94	9.07	79.6
10	Kyle Lohse K. Lohse	316	457	147	143	.507	418	4.40	1,615	12	9	2	2531.2	2,711	1,239	1,327	694	87	15	34	10,839	57	5.74	2.47	2.33	1.12	14.9	6.4	1.34	.295	4.72	105	4.35	105	9.64	-58.3
11	Cole Hamels C. Hamels	310	423	163	122	.572	422	3.43	2,560	17	7	0	2698.0	2,424	1,027	1,103	767	100	0	43	11,115	57	8.54	2.56	3.34	1.03	23.0	6.9	1.18	.287	3.68	82	3.68	88	8.09	151.3
12	Justin Verlander J. Verlander	310	454	226	129	.637	454	3.33	3,013	26	9	0	2988.0	2,538	1,105	1,192	851	98	0	27	12,214	87	9.08	2.56	3.54	0.93	24.7	7.0	1.13	.281	3.59	78	3.40	80	7.64	280.4
13	Dan Haren D. Haren	305	391	153	131	.539	380	3.75	2,013	16	6	1	2419.2	2,357	1,009	1,105	500	67	4	39	10,022	98	7.49	1.86	4.03	1.13	20.1	5.0	1.18	.288	4.11	92	3.77	92	8.77	92.8
14	Jamie Moyer J. Moyer	301	350	151	108	.583	344	4.30	1,277	13	4	0	2145.2	2,203	1,025	1,093	588	88	2	33	9,128	21	5.36	2.47	2.17	1.26	14.0	6.4	1.30	.277	4.58	99	4.65	106	9.24	-66
15	Aaron Harang A. Harang	298	387	128	143	.472	381	4.26	1,842	15	8	0	2322.0	2,445	1,099	1,177	712	63	2	54	9,975	76	7.14	2.76	2.59	1.16	18.5	7.1	1.36	.304	4.56	103	4.17	100	9.48	12.3
16	Livan Hernandez L. Hernandez	297	438	151	150	.502	394	4.45	1,596	39	9	1	2655.2	2,949	1,312	1,404	846	67	17	72	11,472	35	5.41	2.87	1.89	1.01	13.9	7.4	1.43	.306	4.76	105	4.35	102	9.99	-29.4
17	Jon Lester J. Lester	294	452	200	117	.631	451	3.66	2,488	15	4	0	2740.0	2,610	1,114	1,215	892	90	0	13	11,487	63	8.17	2.93	2.79	0.97	21.7	7.8	1.28	.300	3.99	86	3.77	92	8.57	101.7
18	Max Scherzer M. Scherzer	287	407	190	97	.662	398	3.16	3,020	12	5	0	2536.2	2,072	890	959	677	96	2	20	10,266	73	10.71	2.40	4.46	1.02	29.4	6.6	1.08	.289	3.40	76	3.12	75	7.35	288.2
19	Ted Lilly T. Lilly	286	347	130	112	.537	328	4.10	1,653	5	3	0	1959.0	1,797	893	954	652	60	4	35	8,280	57	7.59	3.00	2.54	1.31	20.0	7.9	1.25	.268	4.38	95	4.38	101	8.26	-10
20	Barry Zito B. Zito	282	433	165	143	.536	421	4.04	1,885	12	5	0	2576.2	2,381	1,157	1,254	1,064	97	9	52	11,001	50	6.58	3.72	1.77	0.98	17.1	9.7	1.34	.274	4.38	97	4.38	104	8.32	-43.1
21	Jeff Suppan J. Suppan	277	360	120	121	.498	342	4.58	1,137	11	4	0	2097.2	2,332	1,068	1,173	733	85	10	51	9,197	74	4.88	3.14	1.55	1.19	12.4	8.0	1.46	.295	5.03	104	4.88	111	10.01	-109
22	Randy Wolf R. Wolf	276	368	127	116	.523	358	4.17	1,698	13	9	1	2206.2	2,184	1,022	1,095	764	98	3	39	9,425	40	6.93	3.12	2.22	1.13	18.0	8.1	1.34	.290	4.47	100	4.33	102	8.91	-19.6
23	Tim Wakefield T. Wakefield	268	411	121	113	.517	292	4.46	1,386	8	0	7	2041.2	1,980	1,011	1,130	699	120	46	22	8,764	97	6.11	3.08	1.98	1.18	15.8	8.0	1.31	.272	4.98	97	4.62	108	8.73	-80
24	Freddy Garcia F. Garcia	267	343	139	100	.582	324	4.16	1,451	10	3	0	2062.2	2,038	954	1,005	618	57	13	38	8,707	83	6.33	2.70	2.35	1.16	16.7	7.1	1.29	.280	4.39	95	4.31	97	8.89	30.2
25	Ian Kennedy I. Kennedy	265	424	100	106	.485	290	4.10	1,710	2	1	56	1837.2	1,733	838	900	618	81	97	25	7,793	76	8.37	3.03	2.77	1.30	21.9	7.9	1.28	.287	4.41	101	4.26	107	8.49	-56.7