Sammy Sosa hit the most home runs in 2000, with 50 homers.

	NAME	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Sammy Sosa S. Sosa	50	2000	CHC	156	604	106	193	38	1	138	91	2	168	7	4	705	383	89	0	8	19	12	.320	.406	.634	1.040	146	53.4	.428	154	51.8
2	Barry Bonds B. Bonds	49	2000	SFG	143	480	129	147	28	4	106	117	3	77	11	3	607	330	81	0	7	22	6	.306	.440	.688	1.127	141	61	.456	174	61.2
3	Jeff Bagwell J. Bagwell	47	2000	HOU	159	590	152	183	37	1	132	107	15	116	9	6	719	363	85	0	7	11	19	.310	.424	.615	1.039	153	59	.435	153	51.8
4	Troy Glaus T. Glaus	47	2000	ANA	159	563	120	160	37	1	102	112	2	163	14	11	678	340	85	0	1	6	14	.284	.404	.604	1.008	138	49	.424	150	46
5	Vladimir Guerrero V. Guerrero	44	2000	MON	154	571	101	197	28	11	123	58	8	74	9	10	641	379	83	0	4	23	15	.345	.410	.664	1.074	139	55.1	.439	160	52
6	Richard Hidalgo R. Hidalgo	44	2000	HOU	153	558	118	175	42	3	122	56	21	110	13	6	644	355	89	0	9	3	13	.314	.391	.636	1.028	133	48.7	.428	148	42.3
7	Jason Giambi J. Giambi	43	2000	OAK	152	510	108	170	29	1	137	137	9	96	2	0	664	330	73	0	8	6	9	.333	.476	.647	1.123	163	75.5	.471	182	74.3
8	Gary Sheffield G. Sheffield	43	2000	LAD	141	501	105	163	24	3	109	101	4	71	4	6	612	322	70	0	6	7	13	.325	.438	.643	1.081	139	58.8	.451	174	61.5
9	Frank Thomas F. Thomas	43	2000	CWS	159	582	115	191	44	0	143	112	5	94	1	3	707	364	87	0	8	18	13	.328	.436	.625	1.061	155	61.7	.441	160	57.6
10	Jim Edmonds J. Edmonds	42	2000	STL	152	525	129	155	25	0	108	103	6	167	10	3	643	306	67	1	8	3	5	.295	.411	.583	.994	129	44.8	.421	149	42.6
11	Todd Helton T. Helton	42	2000	COL	160	580	138	216	59	2	147	103	4	61	5	3	697	405	103	0	10	22	12	.372	.463	.698	1.162	174	82.4	.476	161	58
12	Tony Batista T. Batista	41	2000	TOR	154	620	96	163	32	2	114	35	6	121	5	4	664	322	75	0	3	1	15	.263	.307	.519	.827	92	4.5	.348	100	-0.2
13	Carlos Delgado C. Delgado	41	2000	TOR	162	569	115	196	57	1	137	123	15	104	0	1	711	378	99	0	4	18	12	.344	.470	.664	1.134	174	81	.471	179	76
14	David Justice D. Justice	41	2000	TOT	146	524	89	150	31	1	118	77	1	91	2	1	605	306	73	0	3	3	13	.286	.377	.584	.961	113	33.6	.404	137	30.6
15	Alex Rodriguez A. Rodriguez	41	2000	SEA	148	554	134	175	34	2	132	100	7	121	15	4	672	336	77	0	11	5	10	.316	.420	.606	1.026	141	52.7	.431	158	53.3
16	Ken Griffey Jr. K. Griffey Jr.	40	2000	CIN	145	520	100	141	22	3	118	94	9	117	6	4	631	289	65	0	8	17	7	.271	.387	.556	.942	111	28.2	.392	127	23.5
17	Rafael Palmeiro R. Palmeiro	39	2000	TEX	158	565	102	163	29	3	120	103	3	77	2	1	678	315	71	0	7	17	14	.288	.397	.558	.954	124	34.5	.399	130	28
18	Mike Piazza M. Piazza	38	2000	NYM	136	482	90	156	26	0	113	58	3	69	4	2	545	296	64	0	2	10	15	.324	.398	.614	1.012	110	38.9	.423	153	39.1
19	Manny Ramirez M. Ramirez	38	2000	CLE	118	439	92	154	34	2	122	86	3	117	1	1	532	306	74	0	4	9	9	.351	.457	.697	1.154	133	63	.477	181	58.6
20	Edgar Martinez E. Martinez	37	2000	SEA	153	556	100	180	31	0	145	96	5	95	3	0	665	322	68	0	8	8	13	.324	.423	.579	1.002	136	48.4	.424	154	49
21	Jim Thome J. Thome	37	2000	CLE	158	557	106	150	33	1	106	118	4	171	1	0	684	296	71	0	5	4	8	.269	.398	.531	.929	124	34.6	.399	131	28.8
22	Andruw Jones A. Jones	36	2000	ATL	161	656	122	199	36	6	104	59	9	100	21	6	729	355	78	0	5	0	12	.303	.366	.541	.907	125	29.7	.387	127	27.2
23	Chipper Jones C. Jones	36	2000	ATL	156	579	118	180	38	1	111	95	2	64	14	7	686	328	75	0	10	10	14	.311	.404	.566	.970	131	40.7	.409	141	38.3
24	Mo Vaughn M. Vaughn	36	2000	ANA	161	614	93	167	31	0	117	79	14	181	2	0	712	306	67	0	5	11	14	.272	.365	.498	.864	111	17.2	.368	115	14.1
25	Garret Anderson G. Anderson	35	2000	ANA	159	647	92	185	40	3	117	24	0	87	7	6	681	336	78	1	9	5	21	.286	.307	.519	.827	92	2.3	.345	99	-0.7