Since 2010, 4 players are tied for the most homers in a game, with 4 homers. The first three are Eugenio Suárez on April 26, J.D. Martinez on September 4, 2017 and Scooter Gennett on June 6, 2017.

Interpreted as:

most home runs by a player in a regular-season game after 2000s

	NAME	HR	DATE	TM		OPP	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Eugenio Suárez E. Suárez	4	4/26/2025	AZ	vs	ATL	4	4	4	0	0	5	0	0	0	0	0	4	16	4	0	0	0	0
2	J.D. Martinez	4	9/4/2017	ARI	@	LAD	5	4	4	0	0	6	0	0	1	0	0	5	16	4	0	0	0	0
3	Scooter Gennett S. Gennett	4	6/6/2017	CIN	vs	STL	5	4	5	0	0	10	0	0	0	0	0	5	17	4	0	0	0	0
4	Josh Hamilton J. Hamilton	4	5/8/2012	TEX	@	BAL	5	4	5	1	0	8	0	0	0	0	0	5	18	5	0	0	0	0
5	Jasson Domínguez J. Domínguez	3	5/9/2025	NYY	@	ATH	4	3	3	0	0	7	0	0	1	0	0	5	12	3	0	1	0	0
6	José Ramírez J. Ramírez	3	4/4/2025	CLE	@	LAA	4	3	3	0	0	4	1	0	1	0	0	5	12	3	0	0	0	0
7	Iván Herrera I. Herrera	3	4/2/2025	STL	vs	LAA	4	3	3	0	0	6	1	0	1	0	0	5	12	3	0	0	0	0
8	Aaron Judge A. Judge	3	3/29/2025	NYY	vs	MIL	6	4	4	1	0	8	0	0	0	0	0	6	14	4	0	0	0	0
9	Triston Casas T. Casas	3	9/22/2024	BOS	vs	MIN	4	3	3	0	0	7	0	0	0	0	0	4	12	3	0	0	0	0
10	Shohei Ohtani S. Ohtani	3	9/19/2024	LAD	@	MIA	6	4	6	2	0	10	0	0	0	2	0	6	17	5	0	0	0	0
11	Pavin Smith P. Smith	3	9/8/2024	ARI	@	HOU	4	3	3	0	0	8	1	0	1	0	0	5	12	3	0	0	0	0
12	Kyle Schwarber K. Schwarber	3	9/3/2024	PHI	@	TOR	6	4	5	1	0	6	0	0	1	0	0	6	15	4	0	0	0	0
13	Lawrence Butler L. Butler	3	8/29/2024	OAK	@	CIN	4	3	3	0	0	4	1	0	0	0	0	5	12	3	0	0	0	0
14	Yordan Alvarez Y. Alvarez	3	8/28/2024	HOU	@	PHI	4	3	4	0	0	4	1	0	0	0	0	5	13	3	0	0	0	0
15	Juan Soto J. Soto	3	8/13/2024	NYY	@	CWS	4	3	3	0	0	4	1	0	0	0	0	5	12	3	0	0	0	0
16	Kyle Schwarber K. Schwarber	3	8/7/2024	PHI	@	LAD	4	3	4	1	0	7	1	0	0	0	0	5	14	4	0	0	0	0
17	Eugenio Suárez E. Suárez	3	7/30/2024	ARI	vs	WSH	6	4	4	0	0	5	0	0	0	0	0	6	13	3	0	0	0	0
18	Michael Toglia M. Toglia	3	7/14/2024	COL	@	NYM	4	3	3	0	0	3	0	0	0	0	0	4	12	3	0	0	0	0
19	Lawrence Butler L. Butler	3	7/14/2024	OAK	@	PHI	6	3	3	0	0	6	0	0	0	0	0	6	12	3	0	0	0	0
20	Ben Rice B. Rice	3	7/6/2024	NYY	vs	BOS	5	3	3	0	0	7	0	0	1	0	0	5	12	3	0	0	0	0
21	Will Smith W. Smith	3	7/5/2024	LAD	vs	MIL	3	4	3	0	0	3	2	0	0	0	0	5	12	3	0	0	0	0
22	Max Muncy M. Muncy	3	5/4/2024	LAD	vs	ATL	5	3	4	0	0	4	0	0	0	0	0	5	13	3	0	0	0	0
23	Travis d'Arnaud T. d'Arnaud	3	4/19/2024	ATL	vs	TEX	4	3	3	0	0	6	0	0	0	0	0	4	12	3	0	0	0	0
24	Shea Langeliers S. Langeliers	3	4/9/2024	OAK	@	TEX	4	3	3	0	0	4	0	0	1	0	0	4	12	3	0	0	0	0
25	Bryce Harper B. Harper	3	4/2/2024	PHI	vs	CIN	4	3	3	0	0	6	0	0	0	0	0	4	12	3	0	0	0	0