David Ortiz and Jim Thome were tied for the most homers by a designated hitter in 2007, with 35 homers.
| NAME | HR | SEASON | TM | G | AB | R | H | 2B | 3B | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | wRC | WRAA | wOBA | wRC+ | BRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Ortiz | 35 | 2007 | 149 | 549 | 116 | 182 | 52 | 1 | 117 | 111 | 4 | 103 | 3 | 1 | 667 | 341 | 88 | 0 | 3 | 12 | 16 | .332 | .445 | .621 | 1.066 | 149 | 66.2 | .449 | 175 | 62.6 | |
| 2 |  | J. Thome | 35 | 2007 | 130 | 432 | 79 | 119 | 19 | 0 | 96 | 95 | 6 | 134 | 0 | 1 | 536 | 243 | 54 | 0 | 3 | 11 | 10 | .275 | .410 | .563 | .973 | 103 | 36.3 | .412 | 150 | 33.4 | |
| 3 |  | J. Cust | 26 | 2007 | 124 | 395 | 61 | 101 | 18 | 1 | 82 | 105 | 1 | 164 | 0 | 2 | 507 | 199 | 45 | 0 | 6 | 2 | 6 | .256 | .408 | .504 | .912 | 91 | 27.9 | .397 | 145 | 28.9 | |
| 4 |  | F. Thomas | 26 | 2007 | 155 | 531 | 63 | 147 | 30 | 0 | 95 | 81 | 7 | 94 | 0 | 0 | 624 | 255 | 56 | 0 | 5 | 3 | 14 | .277 | .377 | .480 | .857 | 99 | 22.1 | .373 | 127 | 21 | |
| 5 | | G. Sheffield | 25 | 2007 | 133 | 494 | 107 | 131 | 20 | 1 | 75 | 84 | 9 | 71 | 22 | 5 | 593 | 228 | 46 | 0 | 6 | 2 | 10 | .265 | .378 | .462 | .839 | 92 | 18.6 | .368 | 123 | 16.8 | |
| 6 | | T. Hafner | 24 | 2007 | 152 | 545 | 80 | 145 | 25 | 2 | 100 | 102 | 7 | 115 | 1 | 1 | 659 | 246 | 51 | 0 | 5 | 17 | 15 | .266 | .385 | .451 | .837 | 99 | 17.1 | .362 | 121 | 17.5 | |
| 7 |  | S. Sosa | 21 | 2007 | 114 | 412 | 53 | 104 | 24 | 1 | 92 | 34 | 3 | 112 | 0 | 0 | 454 | 193 | 46 | 0 | 5 | 3 | 11 | .252 | .311 | .468 | .779 | 57 | 0.5 | .332 | 96 | -2 | |
| 8 | | J. Gomes | 17 | 2007 | 107 | 348 | 48 | 85 | 20 | 2 | 49 | 35 | 7 | 126 | 12 | 4 | 394 | 160 | 39 | 0 | 4 | 1 | 1 | .244 | .322 | .460 | .782 | 51 | 2.3 | .338 | 104 | 2.1 | |
| 9 | | A. Huff | 15 | 2007 | 151 | 550 | 68 | 154 | 34 | 5 | 72 | 48 | 1 | 87 | 1 | 1 | 603 | 243 | 54 | 0 | 4 | 2 | 13 | .280 | .337 | .442 | .778 | 78 | 3.9 | .339 | 104 | 2.8 | |
| 10 | | J. Giambi | 14 | 2007 | 83 | 254 | 31 | 60 | 8 | 0 | 39 | 40 | 8 | 66 | 1 | 0 | 303 | 110 | 22 | 0 | 1 | 2 | 1 | .236 | .356 | .433 | .790 | 42 | 4.5 | .349 | 111 | 4 | |
| 11 | | B. Butler | 8 | 2007 | 92 | 329 | 38 | 96 | 23 | 2 | 52 | 27 | 2 | 55 | 0 | 0 | 360 | 147 | 33 | 0 | 2 | 5 | 8 | .292 | .347 | .447 | .794 | 48 | 3.4 | .342 | 104 | 1.9 | |
| 12 |  | M. Piazza | 8 | 2007 | 83 | 309 | 33 | 85 | 17 | 1 | 44 | 18 | 0 | 61 | 0 | 0 | 329 | 128 | 26 | 0 | 2 | 0 | 9 | .275 | .313 | .414 | .727 | 37 | -3.7 | .318 | 93 | -3 | |
| 13 | | M. Sweeney | 7 | 2007 | 74 | 265 | 26 | 69 | 15 | 1 | 38 | 17 | 5 | 29 | 0 | 0 | 289 | 107 | 23 | 0 | 2 | 4 | 9 | .260 | .315 | .404 | .719 | 31 | -4.9 | .311 | 83 | -6.2 | |
| 14 | | J. Vidro | 6 | 2007 | 147 | 548 | 78 | 172 | 26 | 0 | 59 | 63 | 1 | 57 | 0 | 0 | 625 | 216 | 32 | 5 | 8 | 5 | 21 | .314 | .381 | .394 | .775 | 84 | 7.2 | .345 | 111 | 8.4 | |
| 15 | | S. Hillenbrand | 4 | 2007 | TOT | 73 | 267 | 25 | 67 | 5 | 2 | 31 | 7 | 1 | 30 | 0 | 3 | 278 | 88 | 11 | 0 | 3 | 1 | 9 | .251 | .270 | .330 | .599 | 18 | -16.1 | .262 | 53 | -16.6 |
| 16 | | G. Norton | 4 | 2007 | 75 | 202 | 25 | 49 | 9 | 0 | 23 | 37 | 0 | 55 | 1 | 1 | 240 | 70 | 13 | 0 | 1 | 3 | 1 | .243 | .358 | .347 | .705 | 27 | -2.3 | .319 | 92 | -2.5 | |
| 17 | | J. Cirillo | 2 | 2007 | TOT | 78 | 193 | 24 | 48 | 13 | 2 | 27 | 19 | 1 | 19 | 2 | 0 | 218 | 71 | 17 | 3 | 2 | 0 | 10 | .249 | .316 | .368 | .684 | 22 | -4.8 | .305 | 81 | -5.3 |
| 18 | | J. Clement | 2 | 2007 | 9 | 16 | 4 | 6 | 1 | 0 | 3 | 3 | 0 | 3 | 0 | 0 | 19 | 13 | 3 | 0 | 0 | 0 | 0 | .375 | .474 | .813 | 1.286 | 6 | 3.2 | .530 | 235 | 3.2 | |
| 19 | | G. Jones | 2 | 2007 | 31 | 77 | 7 | 16 | 2 | 1 | 5 | 6 | 0 | 20 | 1 | 1 | 84 | 26 | 5 | 0 | 1 | 0 | 2 | .208 | .262 | .338 | .600 | 6 | -4.7 | .264 | 56 | -4.6 | |
| 20 | | J. Knott | 1 | 2007 | 7 | 14 | 3 | 3 | 0 | 0 | 4 | 4 | 0 | 3 | 0 | 0 | 19 | 6 | 1 | 0 | 1 | 0 | 1 | .214 | .368 | .429 | .797 | 3 | 0.3 | .349 | 111 | 0.3 |
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