Since 1920, Leon Cadore and Joe Oeschger are tied for pitching the most innings in a game, with 26 innings on May 1, 1920.

Interpreted as:

most ip by a player in a regular-season game in the live ball era

	NAME	IP	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Leon Cadore L. Cadore	26.0	5/1/1920	BKN	@	BSN		1	0.35	7	1	0	0	15	1	1	0	5	0	0		96	0
2	Joe Oeschger J. Oeschger	26.0	5/1/1920	BSN	vs	BKN		1	0.35	7	1	0	0	9	1	1	0	4	0	0		90	1
3	Bob Smith B. Smith	22.0	5/17/1927	BSN	vs	CHC	L	1	1.23	5	1	0	0	20	3	4	0	9	0	0		89	0
4	Ted Lyons T. Lyons	21.0	5/24/1929	CWS	vs	DET	L	1	2.57	4	1	0	0	24	6	6	0	2	0	0		85	0
5	George Uhle G. Uhle	20.0	5/24/1929	DET	@	CWS	W	1	2.25	4	0	0	0	17	5	5	0	3	0	0		79	1
6	Les Mueller L. Mueller	19.2	7/21/1945	DET	@	PHA		1	0.00	6	0	0	0	13	0	1	0	5	0	0		74	0
7	Dixie Davis D. Davis	19.0	8/9/1921	SLA	@	WSH	W	1	2.37	8	1	0	0	13	5	6	0	5	0	0		74	0
8	Dana Fillingim D. Fillingim	19.0	5/3/1920	BSN	vs	BKN	W	1	0.00	4	1	0	0	12	0	1	0	4	0	0		72	0
9	Sherry Smith S. Smith	18.1	5/3/1920	BKN	@	BSN	L	1	0.98	3	1	0	0	13	2	2	0	5	0	0		69	0
10	Vern Law V. Law	18.0	7/19/1955	PIT	vs	MIL		1	0.50	12	0	0	0	9	1	2	1	2	0	0	0	64	1
11	Carl Hubbell C. Hubbell	18.0	7/2/1933	NYG	vs	SLN	W	1	0.00	12	1	1	0	6	0	0	0	0	0	0		59	0
12	Guy Bush G. Bush	18.0	5/14/1927	CHC	@	BSN	W	1	1.00	5	1	0	0	11	2	2	0	8	0	0		71	0
13	Charlie Robertson C. Robertson	17.1	5/14/1927	BSN	vs	CHC	L	1	3.12	4	0	0	0	13	6	6	0	4	0	0		66	1
14	Robin Roberts R. Roberts	17.0	9/6/1952	PHN	vs	BSN	W	1	2.65	5	1	0	0	18	5	6	1	3	0	0	1	71	0
15	Mickey McDermott M. McDermott	17.0	7/13/1951	BSA	@	CWS		1	1.06	9	0	0	0	8	2	2	0	9	0	0	0	68	1
16	Saul Rogovin S. Rogovin	17.0	7/12/1951	CWS	vs	BSA	L	1	2.12	9	1	0	0	10	4	5	1	6	0	0	0	63	0
17	Roy Parmelee R. Parmelee	17.0	4/29/1936	SLN	vs	NYG	W	1	0.53	9	1	0	0	6	1	1	0	4	0	0		57	0
18	Dizzy Dean D. Dean	17.0	7/1/1934	SLN	@	CIN	W	1	3.18	7	0	0	0	18	6	6	0	7	1	0		75	0
19	Tony Freitas T. Freitas	17.0	7/1/1934	CIN	vs	SLN		1	3.18	5	0	0	0	17	6	6	1	2	0	0		69	1
20	Vic Sorrell V. Sorrell	17.0	8/13/1933	DET	@	CWS	W	1	1.59	5	1	0	0	17	3	5	0	4	0	0		70	0
21	Eddie Rommel E. Rommel	17.0	7/10/1932	PHA	@	CLE	W	0	6.88	7	0	0	0	29	13	14	0	9	0	1		87	2
22	Lefty Grove L. Grove	17.0	8/14/1929	PHA	@	CLE	W	1	1.59	8	1	0	0	20	3	3	0	4	1	0		77	1
23	Red Lucas R. Lucas	17.0	4/25/1928	CIN	vs	SLN	W	1	2.12	7	1	0	0	12	4	4	1	3	0	0		65	0
24	Grover Alexander G. Alexander	17.0	10/1/1920	CHC	vs	SLN	W	1	0.53	8	1	0	0	16	1	2	0	3	0	0		69	0
25	Ray Fisher R. Fisher	17.0	8/27/1920	CIN	vs	NYG	L	1	3.18	4	1	0	0	18	6	6	0	5	0	0		71	0