11 teams are tied for losing the most games in a game with a run differential of 2 or above, with 1 loss. The first three are the Miami Marlins on September 16, 2016, the Washington Senators on September 30, 1971 and the New York Giants on September 26, 1942.
Interpreted as:
most losses by at least 2 runs in a 25 regular-season game period| TEAM | L | DIFF | DATE | TM | OPP | RESULT | W | L% | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Marlins | 1 | 2 | 9/16/2016 |  MIA | @ |  PHI | L 3-1 | 0 | 1.000 | 52 | 3 | 13 | 4 | 0 | 1 | 3 | 4 | 1 | 12 | 2 | 0 | 57 | 20 | 5 | 0 | 0 | 1 | 2 | .250 | .316 | .385 | .700 |
| 2 |  | Senators | 1 | 2 | 9/30/1971 |  WSH | vs |  NYY | L 7-5 | 0 | 1.000 | 33 | 7 | 11 | 1 | 0 | 1 | 5 | 3 | 0 | 3 | 1 | 1 | 37 | 15 | 2 | 0 | 1 | 1 | 3 | .333 | .378 | .455 | .833 |
| 3 |  | Giants | 1 | 3 | 9/26/1942 |  NYG | vs |  BSN | L 5-2 | 0 | 1.000 | 27 | 5 | 10 | 0 | 1 | 0 | 5 | 5 | 0 | 2 | 1 | 0 | 33 | 12 | 1 | 1 | 2 | .370 | .469 | .444 | .913 | ||
| 4 |  | Senators | 1 | 3 | 8/15/1941 |  WSH | vs |  BSA | L 6-3 | 0 | 1.000 | 29 | 6 | 10 | 2 | 1 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 33 | 14 | 3 | 0 | 1 | .345 | .424 | .483 | .907 | ||
| 5 |  | Cubs | 1 | 2 | 10/5/1907 |  CHC | @ |  SLN | L 2-0 | 0 | 1.000 | 17 | 2 | 6 | 2 | 0 | 0 | 1 | 0 | 0 | 18 | 8 | 2 | 0 | .353 | .389 | .471 | .859 | ||||||
| 6 |  | Pirates | 1 | 3 | 6/1/1897 |  PIT | @ |  NYG | L 7-4 | 0 | 1.000 | 7 | ||||||||||||||||||||||
| 7 |  | Colts | 1 | 2 | 4/23/1892 |  CHI | vs | LOU | L 4-2 | 0 | 1.000 | 4 | ||||||||||||||||||||||
| 8 |  | Orioles | 1 | 3 | 10/5/1891 |  BAL | @ |  WSH | L 4-1 | 0 | 1.000 | 4 | ||||||||||||||||||||||
| 9 | Gladiators | 1 | 5 | 7/27/1890 | BKA | vs | COL | L 13-8 | 0 | 1.000 | 13 | |||||||||||||||||||||||
| 10 | Spiders | 1 | 2 | 7/22/1887 | CLE | @ |  PHA | L 6-4 | 0 | 1.000 | 6 | |||||||||||||||||||||||
| 11 | Cowboys | 1 | 3 | 8/22/1884 | KCC | vs | SLU | L 6-3 | 0 | 1.000 | 6 | |||||||||||||||||||||||
| 12 | Grays | 1 | 2 | 7/4/1883 | PRO | @ | PHN | L 11-9 | 0 | 1.000 | 11 |
Some of the information used here was obtained free of charge from Retrosheet.
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